(10 nodes) Peptidase C1A network (Drosophila melanogaster)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CG5367	Uncharacterized protein; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; immune response; Belongs to the peptidase C1 family. (338 aa)
	CG12163	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family. (614 aa)
	26-29-p	Homologue of Sarcophaga 26,29kDa proteinase; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family. (549 aa)
	Swim	Secreted Wg-interacting molecule (Swim) encodes a secreted protein that binds to the product of wg and may function in its spreading; Belongs to the peptidase C1 family. (431 aa)
	CtsB1	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family. (340 aa)
	CG6337	RE20049p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family. (340 aa)
	CG11459	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family. (336 aa)
	CG6347	LD36817p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family. (352 aa)
	Cp1	Cathepsin L heavy chain; Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion; Belongs to the peptidase C1 family. (371 aa)
	CG4847	RH39096p; Cysteine-type peptidase activity; cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; proteolysis; multicellular organism reproduction; Belongs to the peptidase C1 family. (420 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG11459	CG12163	FBpp0310707	FBpp0078465	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family.	0.634
CG11459	CG5367	FBpp0310707	FBpp0079644	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	Uncharacterized protein; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; immune response; Belongs to the peptidase C1 family.	0.483
CG11459	Cp1	FBpp0310707	FBpp0086719	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	Cathepsin L heavy chain; Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion; Belongs to the peptidase C1 family.	0.907
CG11459	CtsB1	FBpp0310707	FBpp0311925	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family.	0.745
CG12163	CG11459	FBpp0078465	FBpp0310707	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family.	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	0.634
CG12163	CG5367	FBpp0078465	FBpp0079644	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family.	Uncharacterized protein; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; immune response; Belongs to the peptidase C1 family.	0.561
CG12163	Cp1	FBpp0078465	FBpp0086719	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family.	Cathepsin L heavy chain; Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion; Belongs to the peptidase C1 family.	0.767
CG12163	CtsB1	FBpp0078465	FBpp0311925	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family.	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family.	0.857
CG4847	CtsB1	FBpp0086091	FBpp0311925	RH39096p; Cysteine-type peptidase activity; cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; proteolysis; multicellular organism reproduction; Belongs to the peptidase C1 family.	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family.	0.458
CG5367	CG11459	FBpp0079644	FBpp0310707	Uncharacterized protein; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; immune response; Belongs to the peptidase C1 family.	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	0.483
CG5367	CG12163	FBpp0079644	FBpp0078465	Uncharacterized protein; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; immune response; Belongs to the peptidase C1 family.	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family.	0.561
CG5367	Cp1	FBpp0079644	FBpp0086719	Uncharacterized protein; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; immune response; Belongs to the peptidase C1 family.	Cathepsin L heavy chain; Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion; Belongs to the peptidase C1 family.	0.461
CG5367	CtsB1	FBpp0079644	FBpp0311925	Uncharacterized protein; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; immune response; Belongs to the peptidase C1 family.	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family.	0.531
CG6337	CtsB1	FBpp0311787	FBpp0311925	RE20049p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family.	0.409
Cp1	CG11459	FBpp0086719	FBpp0310707	Cathepsin L heavy chain; Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion; Belongs to the peptidase C1 family.	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	0.907
Cp1	CG12163	FBpp0086719	FBpp0078465	Cathepsin L heavy chain; Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion; Belongs to the peptidase C1 family.	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family.	0.767
Cp1	CG5367	FBpp0086719	FBpp0079644	Cathepsin L heavy chain; Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion; Belongs to the peptidase C1 family.	Uncharacterized protein; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; immune response; Belongs to the peptidase C1 family.	0.461
Cp1	CtsB1	FBpp0086719	FBpp0311925	Cathepsin L heavy chain; Important for the overall degradation of proteins in lysosomes. Essential for adult male and female fertility. May play a role in digestion; Belongs to the peptidase C1 family.	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family.	0.861
CtsB1	CG11459	FBpp0311925	FBpp0310707	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family.	GH15170p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.	0.745
CtsB1	CG12163	FBpp0311925	FBpp0078465	Cathepsin B1 (CtsB1) encodes a papain-like cysteine proteinase involved in lysosomal protein degradation; Belongs to the peptidase C1 family.	Putative cysteine proteinase CG12163; May have a role in autophagic cell death. Belongs to the peptidase C1 family.	0.857