STRINGSTRING
Gr59a Gr59a Gr8a Gr8a Gr39a Gr39a Gr36c Gr36c Gr36b Gr36b Gr36a Gr36a Gr33a Gr33a Gr32a Gr32a Gr28a Gr28a Gr77a Gr77a Gr21a Gr21a Gr22f Gr22f Gr22c Gr22c Gr22a Gr22a Gr22e Gr22e Gr23a Gr23a Gr68a Gr68a Gr10b Gr10b Gr59e Gr59e Gr59f Gr59f Gr59c Gr59c Gr59d Gr59d Gr59b Gr59b Gr58b Gr58b Gr58a Gr58a Gr58c Gr58c Gr9a Gr9a Gr22b Gr22b Gr63a Gr63a Gr93b Gr93b CG32395 CG32395 Gr2a Gr2a Gr66a Gr66a Gr47a Gr47a Gr22d Gr22d Gr43a Gr43a Gr97a Gr97a Gr10a Gr10a Gr28b Gr28b Gr89a Gr89a Gr57a Gr57a Gr98d Gr98d Gr98c Gr98c Gr98b Gr98b Gr98a Gr98a Gr94a Gr94a Gr93c Gr93c Gr93d Gr93d Gr93a Gr93a Gr92a Gr92a Gr85a Gr85a Gr39b Gr39b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gr59aGustatory receptor; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. (367 aa)
Gr8aGustatory receptor 8a; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Required for sensing and avoiding L-canavanine, a plant-derived insecticide. (385 aa)
Gr39aGustatory and pheromone receptor 39a, isoform C; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Plays a role in sustaining courtship behavior in males, possibly through the reception of a stimulating arrestant pheromone. (381 aa)
Gr36cPutative gustatory receptor 36c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (390 aa)
Gr36bPutative gustatory receptor 36b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (391 aa)
Gr36aPutative gustatory receptor 36a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr22e subfamily. (391 aa)
Gr33aGustatory and pheromone receptor 33a; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Required for sensing all nonvolatile repulsive chemicals, including tastants, pheromones, and especially N,N-Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide. Functions also as a pheromone receptor for a male inhibitory pheromone leading to male-male courtship suppression. Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr66a subfamily. (475 aa)
Gr32aGustatory and pheromone receptor 32a; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Required for the response to N,N-Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide. Functions as a pheromone receptor for a male inhibitory pheromone and promotes male-male aggression and suppresses male-male courtship. Also promotes preferentially virgin females courting over mated females. Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily. (461 aa)
Gr28aPutative gustatory receptor 28a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression suggests also nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory modalities. It is also possible that it has chemosensory roles in the detection of internal ligands. (450 aa)
Gr77aPutative gustatory receptor 77a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (449 aa)
Gr21aGustatory and odorant receptor 21a; Gustatory and odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr21a and Gr63a together are sufficient for carbon dioxide detection and avoidance behavior. It is possible that the CO(2) receptors Gr63a and Gr21a activate the TRPC channels through Galpha49B and Plc21C. This innate olfactory avoidance behavior can be inhibited by inhibitory interactions of the odors such as 1-hexanol and 2,3-butanedione with Gr21a and Gr63a. Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr [...] (447 aa)
Gr22fPutative gustatory receptor 22f; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (378 aa)
Gr22cPutative gustatory receptor 22c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (383 aa)
Gr22aPutative gustatory receptor 22a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (394 aa)
Gr22eGustatory receptor for bitter taste 22e; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Seems to be involved in the sensing of bitter taste since it is expressed in neurons that mediate sensitivity to bitter compounds which are also avoidance-type taste neurons. (389 aa)
Gr23aGustatory receptor 23a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily. (374 aa)
Gr68aGustatory receptor 68a; Dsx-dependent essential component of pheromone-driven courtship behavior. Recognizes a female pheromone involved in the second step (tapping step) of the courtship display which is essential for efficient execution of the entire courtship sequence and timely mating. Required for detection of the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males. Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) and courtship suppression is mediated by the rele [...] (389 aa)
Gr10bPutative gustatory receptor 10b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily. (373 aa)
Gr59ePutative gustatory receptor 59e; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (399 aa)
Gr59fPutative gustatory receptor 59f; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (406 aa)
Gr59cPutative gustatory receptor 59c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (397 aa)
Gr59dPutative gustatory receptor 59d; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (390 aa)
Gr59bGustatory receptor; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. (366 aa)
Gr58bPutative gustatory receptor 58b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (408 aa)
Gr58aPutative gustatory receptor 58a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (395 aa)
Gr58cPutative gustatory receptor 58c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily. (412 aa)
Gr9aPutative gustatory receptor 9a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (341 aa)
Gr22bPutative gustatory receptor 22b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Seems to be involved in the sensing of bitter taste since it is expressed in neurons that mediate sensitivity to bitter compounds. (386 aa)
Gr63aGustatory and odorant receptor 63a; Gustatory and odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr21a and Gr63a together are sufficient for carbon dioxide detection and avoidance behavior. It is possible that the CO(2) receptors Gr63a and Gr21a activate the TRPC channels through Galpha49B and Plc21C. This innate olfactory avoidance behavior can be inhibited by inhibitory interactions of the odors such as 1-hexanol and 2,3-butanedione with Gr21a and Gr63a. (489 aa)
Gr93bPutative gustatory receptor 93b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (395 aa)
CG32395Uncharacterized protein CG32395; It is involved in the biological process described with: sensory perception of taste. (371 aa)
Gr2aPutative gustatory receptor 2a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its not yet determined substrates. Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily. (428 aa)
Gr66aGustatory receptor for bitter taste 66a; Gustatory receptor required for response to the bitter in taste neurons. Gr66a cells respond to bitter compounds such as caffeine, theophylline, threonine or valine. Flies avoid bitter substances, suggesting that Gr66a neuron activity is sufficient to mediate avoidance behavior. Required for sensing and avoiding N,N- Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide, as well as to L-canavanine, a plant-derived insecticide. Gr66a neurons are also involved in the sex-specific perception of molecules inducing male avoid [...] (527 aa)
Gr47aGustatory receptor; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. (361 aa)
Gr22dGustatory receptor 22d (Gr22d) encodes a transmembrane domain protein unrelated to GPCRs that is predicted to mediate response to non-volatile compounds. (387 aa)
Gr43aGustatory receptor for sugar taste 43a; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr43a is the main sugar receptor in larvae. Functions as a narrowly tuned fructose receptor in taste neurons but also as a fructose receptor in the brain. Necessary and sufficient to sense hemolymph fructose and promote feeding in hungry flies but suppress feeding in satiated flies. (453 aa)
Gr97aPutative gustatory receptor 97a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (425 aa)
Gr10aGustatory receptor 10a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (408 aa)
Gr28bPutative gustatory receptor 28b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression suggests also nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory modalities. It is also possible that it has chemosensory roles in the detection of internal ligands; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr66a subfamily. (470 aa)
Gr89aPutative gustatory receptor 89a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr77a subfamily. (362 aa)
Gr57aPutative gustatory receptor 57a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (416 aa)
Gr98dPutative gustatory receptor 98d; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily. (412 aa)
Gr98cPutative gustatory receptor 98c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily. (408 aa)
Gr98bPutative gustatory receptor 98b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily. (403 aa)
Gr98aPutative gustatory receptor 98a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily. (391 aa)
Gr94aPutative gustatory receptor 94a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (404 aa)
Gr93cPutative gustatory receptor 93c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. (397 aa)
Gr93dGustatory receptor; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. (381 aa)
Gr93aGustatory receptor for bitter taste 93a; Gustatory receptor required for response to the bitter in taste neurons. Gr93a cells respond to bitter compounds such as caffeine. Flies avoid bitter substances, suggesting that Gr93a neuron activity is sufficient to mediate avoidance behavior. Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr93a subfamily. (419 aa)
Gr92aPutative gustatory receptor 92a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr93a subfamily. (386 aa)
Gr85aPutative gustatory receptor 85a; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr22e subfamily. (397 aa)
Gr39bPutative gustatory receptor 39b; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Has also atypical sensory function in organ not limited to conventional taste sensing like abdominal ganglions. (369 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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