STRINGSTRING
Klp3A Klp3A Klp59C Klp59C Klp61F Klp61F pav pav Klp10A Klp10A nod nod Klp68D Klp68D Klp64D Klp64D Klp31E Klp31E cana cana neb neb Klp98A Klp98A sub sub unc-104 unc-104 Khc Khc Kif3C Kif3C Khc-73 Khc-73 cmet cmet ncd ncd Klp54D Klp54D
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene fusions
gene co-occurrence
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textmining
co-expression
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Klp3AKinesin-like protein at 3A (Klp3A) encodes a microtubule motor protein involved in chromosome segregation and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1212 aa)
Klp59CKinesin-like protein Klp59C; Required during anaphase to drive sister chromatid separation to actively depolymerize kinetochore microtubules at their kinetochore- associated plus ends, thereby contributing to chromatid mobility through a 'Pac-man' mechanism. (626 aa)
Klp61FKinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] (1066 aa)
pavKinesin-like protein; Pavarotti (pav) encodes a microtubule motor protein from the Kinesin superfamily. It plays important roles during the mitotic cycle including spindle formation, cortical cytoskeleton reorganization and cytokinesis. It also negatively regulates Wnt activity. (887 aa)
Klp10AKinesin-like protein Klp10A; Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a 'poleward flux'. Involved in asymmetric cell division of sensory organ precursor (SOP) cells by playing a role in the asymmetric localization of Sara- expressing endosomes to the pIIa daughter cell but not to the pIIb cell. Klp98A targets Sara-expressing endosomes to the central spindle which is symmetrically arranged in early cell division. During late cyto [...] (805 aa)
nodKinesin-like protein Nod; No distributive disjunction (nod) encodes a kinesin-like protein that is important for nonexchange chromosome biology. The nod product is necessary for chromosome segregation during meiosis and for proper chromosome alignment along the meiotic spindle. (666 aa)
Klp68DKinesin-like protein at 68D (Klp68D) encodes the kinesin-2beta motor subunit of the heterotrimeric kinesin-2. It associates with the products of Klp64D and Kap3. It plays an essential role in the sensory cilia assembly, microtubule organization in dendrites, and axonal transport. (784 aa)
Klp64DKinesin-like protein at 64D (Klp64D) encodes the kinesin-2alpha motor subunit of the heterotrimeric kinesin-2. It associates with the products of Klp68D and Kap3. It plays an essential role in sensory cilia assembly and axonal transport; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (677 aa)
Klp31EKinesin-like protein at 31E, isoform A; Microtubule binding; ATPase activity; ATP binding; microtubule motor activity. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1048 aa)
canaCENP-ana, isoform A; CENP-ana (cana) encodes a kinetochore kinesin that contributes to metaphase chromosome alignment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1931 aa)
nebLP17758p; Nebbish (neb) encodes a microtubule motor protein that interacts with PP1 phosphatases and is involved in chromosome segregation; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1121 aa)
Klp98AKinesin-like protein Klp98A; Plus end-directed motor protein involved in asymmetric cell division of sensory organ precursor (SOP) cells by playing a role in the asymmetric localization of Sara-expressing endosomes to the pIIa daughter cell but not to the pIIb cell. Targets Sara-expressing endosomes to the central spindle which is symmetrically arranged in early cell division. During late cytokinesis, central spindle asymmetry is generated by enrichment of Patronin on the pIIb side which protects microtubules from depolymerization by Klp10A while unprotected microtubules on the pIIa si [...] (1265 aa)
subKinesin-like protein subito; Subito (sub) encodes a kinesin-6 homolog. Kinesin-6 proteins are known to bundle antiparallel microtubules. The product of sub is required for cytokinesis in mitosis and spindle organization and chromosome segregation in female meiosis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (628 aa)
unc-104Kinesin-like protein unc-104; Required for presynaptic maturation, has a role in axonal transport of dense-core vesicles carrying synaptic vesicle precursors, components required for the morphological transformation of axonal growth cones to mature boutons; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily. (1739 aa)
KhcKinesin heavy chain; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Milt and Miro form an essential protein complex that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily. (975 aa)
Kif3CKinesin-like protein; It is involved in the biological process described with: microtubule-based movement; cell projection organization; anterograde dendritic transport of neurotransmitter receptor complex; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (649 aa)
Khc-73Kinesin heavy chain 73 (Khc-73) encodes a member of the Kinesin-3 family of microtubule-based transport motors. It facilitates endosomal transport during interphase and modulates cortical polarity during asymmetric neuroblast cell division; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1957 aa)
cmetCENP-meta, isoform C; CENP-meta (cmet) encodes a kinetochore kinesin that contributes to metaphase chromosome alignment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2189 aa)
ncdProtein claret segregational; Non-claret disjunctional (ncd) encodes a minus-end-directed kinesin microtubule motor protein and the sole member of the kinesin-14 motor family. It is required for spindle assembly in oocytes and chromosome attachment to spindles in early embryos; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily. (700 aa)
Klp54DKinesin-like protein; Microtubule binding; ATPase activity; ATP binding; microtubule motor activity. It is involved in the biological process described with: microtubule-based movement; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (760 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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