STRINGSTRING
Pdp Pdp CG10417 CG10417 fig fig alph alph Ppm1 Ppm1 CG15035 CG15035 CG6036 CG6036 CG9801 CG9801 CG10376 CG10376 CG7115 CG7115 CG17746 CG17746 Pp2C1 Pp2C1 Phlpp Phlpp CG17598 CG17598 CG12091 CG12091
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PdpPyruvate dehydrogenase phosphatase (Pdp) encodes an enzyme that regulates the BMP/DPP pathway via dephosporylation of the product encoded by Mad. (475 aa)
CG10417Cation binding; protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. (662 aa)
figProtein phosphatase PTC7 homolog fig; Protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: dephosphorylation; regulation of ubiquinone biosynthetic process; protein dephosphorylation. (314 aa)
alphAlphabet, isoform E; Alphabet (alph) encodes a Ser/Thr phosphatase that regulates RAS/MAPK signaling. (374 aa)
Ppm1AT28366p; Cation binding; protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. (352 aa)
CG15035Phosphoprotein phosphatase activity; protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; Belongs to the PP2C family. (374 aa)
CG6036Protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; magnesium ion binding; manganese ion binding. It is involved in the biological process described with: protein dephosphorylation; negative regulation of stress-activated MAPK cascade. (371 aa)
CG9801PP2C-like domain-containing protein CG9801; Catalytic activity. (709 aa)
CG10376SD03870p; Magnesium-dependent protein serine/threonine phosphatase activity; protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; negative regulation of protein kinase activity. (428 aa)
CG7115Uncharacterized protein, isoform A; Cation binding; magnesium-dependent protein serine/threonine phosphatase activity; protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. (524 aa)
CG17746LD28127p; Protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity; cation binding. It is involved in the biological process described with: protein dephosphorylation. (371 aa)
Pp2C1Protein phosphatase 2C, isoform A; Cation binding; mitogen-activated protein kinase binding; magnesium-dependent protein serine/threonine phosphatase activity; oxidoreductase activity; protein serine/threonine phosphatase activity. It is involved in the biological process described with: oxidation-reduction process; protein dephosphorylation. (1427 aa)
PhlppProtein phosphatase PHLPP-like protein; Protein phosphatase that specifically mediates dephosphorylation of 'Ser-586' of Akt1, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-586' of Akt1 triggers apoptosis and suppression of tumor growth. (954 aa)
CG17598GM14138p; Protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity; cation binding; [pyruvate dehydrogenase (lipoamide)] phosphatase activity. It is involved in the biological process described with: positive regulation of pyruvate dehydrogenase activity; dephosphorylation; protein dephosphorylation. (651 aa)
CG12091Protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; Belongs to the PP2C family. (321 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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