STRINGSTRING
MRP MRP CG5789 CG5789 Sur Sur Pmp70 Pmp70 CG4562 CG4562 CG31792 CG31792 Hmt-1 Hmt-1 CG31793 CG31793 CG7806 CG7806 CG10226 CG10226 Mdr65 Mdr65 CG1824 CG1824 ABCB7 ABCB7 CG10505 CG10505 CG3156 CG3156 CG7627 CG7627 CG9270 CG9270 ABCD ABCD Mdr49 Mdr49 Mdr50 Mdr50 rdog rdog l(2)03659 l(2)03659 Mrp4 Mrp4 CG11898 CG11898
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MRPMultidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport. (1549 aa)
CG5789FI20190p1; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (1402 aa)
SurATP-binding cassette sub-family C member Sur; May function as regulatory subunit of ATP-sensitive potassium channels (KATP) and form KATP channels with a member of the ATP- sensitive inward rectifier potassium channel family (By similarity). May also have channel activity by itself (in vitro). May protect the heart during hypoxia. May protect against heart failure under conditions of tachycardic stress. (2223 aa)
Pmp70Peroxisomal membrane protein 70 kDa, isoform A; Protein homodimerization activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: long-chain fatty acid import into peroxisome. (665 aa)
CG4562Uncharacterized protein, isoform E; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (1408 aa)
CG31792Uncharacterized protein, isoform B; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. (1323 aa)
Hmt-1Heavy metal tolerance factor 1; It is involved in the biological process described with: heme transport; transmembrane transport; response to cadmium ion. (866 aa)
CG31793LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. (1307 aa)
CG7806LD42916p; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (1487 aa)
CG10226Uncharacterized protein, isoform A; Efflux transmembrane transporter activity; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity; ATPase-coupled xenobiotic transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; xenobiotic transport. (1320 aa)
Mdr65Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. (1302 aa)
CG1824GH19726p; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (761 aa)
ABCB7ATP binding cassette subfamily B member 7 (ABCB7) encodes a transporter that likely dimerizes to form a functional transporter. It may act in the mitochondria to transport substrates necessary for the maturation of ICS proteins, which are involved in iron homeostasis. (743 aa)
CG10505Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. (1312 aa)
CG3156LD18126p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: mitochondrial transport; transmembrane transport. (692 aa)
CG7627FI20146p1; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; wound healing. (1355 aa)
CG9270Uncharacterized protein; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport. (1292 aa)
ABCDATP-binding cassette sub-family D member; Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis. Thus, plays a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation, mitochondrial function and microsomal fatty acid elongation; Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily. (730 aa)
Mdr49Multidrug resistance protein homolog 49; Multi drug resistance 49 (Mdr49) encodes drug transmembrane transporter that belongs to the ABCB transporter subfamily and contributes to insecticide resistance. (1302 aa)
Mdr50Multi drug resistance 50; Efflux transmembrane transporter activity; ATPase-coupled xenobiotic transmembrane transporter activity; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: response to insecticide; response to toxic substance; xenobiotic transport; transmembrane transport; renal tubular secretion. (1313 aa)
rdogRed dog mine, isoform A; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: transmembrane transport. (1374 aa)
l(2)03659Probable multidrug resistance-associated protein lethal(2)03659; Vital for development. (1374 aa)
Mrp4Multidrug resistance protein 4 (Mrp4) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in the response to oxidative stress and hypoxia. (1316 aa)
CG11898Uncharacterized protein; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: transmembrane transport. (1320 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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