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MsR2 MsR2 Proc-R Proc-R CapaR CapaR moody moody MsR1 MsR1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
MsR2Myosuppressin receptor 2 (MsR2) encodes a G protein coupled receptor activated by the product of Ms (TDVDHVFLRFamide). It elevates neurotransmitter release in motor neurons and aids larval escape responses to light. (647 aa)
Proc-RG protein-coupled receptor activity; proctolin receptor activity; neuropeptide receptor activity. It is involved in the biological process described with: G protein-coupled receptor signaling pathway; neuropeptide signaling pathway. (545 aa)
CapaRNeuropeptides capa receptor; Acts as a receptor for the neuropeptides CAP-1 and CAP-2, but not CAP-3. Probably a component of signal transduction pathway that leads to Malpighian tubule fluid secretion in response to these ligands. (477 aa)
moodyG-protein coupled receptor moody; Isoform A and isoform B are required in glia to regulate the acute sensitivity to cocaine and to continuously maintain the proper blood-brain barrier (BBB) function. A moody-mediated signaling pathway functions in glia to regulate nervous system insulation and drug- related behaviors. Galphai and Galphao, and the regulator of G protein signaling, loco, are required in the surface glia to achieve effective insulation. The components function by regulating the cortical actin and thereby stabilizing the extended morphology of the surface glia, which in tu [...] (670 aa)
MsR1Myosuppressin receptor 1 (MsR1) encodes a class A transmembrane G protein coupled receptor that binds the neuropeptide ligand encoded by Ms and acts through the adenylate cyclase-inhibiting GPCR signaling pathway. It inhibits visceral muscle contraction, and negatively regulates cardiac contractility and gut motility. (556 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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