9 items (Drosophila melanogaster) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Your Input:
	Sec8	Exocyst complex component 4; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Involved in regulation of synaptic microtubule formation, and also regulation of synaptic growth and glutamate receptor trafficking. Does not appear to be required for basal neurotransmission. (985 aa)
	PICK1	Membrane curvature sensor activity; phospholipid binding; protein kinase C binding; protein domain specific binding. (577 aa)
	GluRIIC	Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission. (940 aa)
	GluRIIE	Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport. (897 aa)
	GluRIIB	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (913 aa)
	cora	Protein 4.1 homolog; An integral component of the septate junction. May play a role in cell-cell interactions that are necessary for proper development. Vital for embryonic development. (1698 aa)
	GluRIID	Glutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (902 aa)
	polo	Serine/threonine-protein kinase polo; May play a role in regulating both nuclear and cytoplasmic aspects of the mitotic cycle. Regulates localization of the augmin complex during mitosis by ensuring its location on mitotic spindles. Also regulates augmin complex localization during male meiosis by promoting its placement at kinetochores while preventing its association with spindle microtubules ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. (576 aa)
	GluRIIA	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (907 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GluRIIA	GluRIIB	FBpp0078739	FBpp0088541	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.948
GluRIIA	GluRIIC	FBpp0078739	FBpp0307912	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission.	0.835
GluRIIA	GluRIID	FBpp0078739	FBpp0083346	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.898
GluRIIA	GluRIIE	FBpp0078739	FBpp0110134	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport.	0.896
GluRIIA	PICK1	FBpp0078739	FBpp0309442	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Membrane curvature sensor activity; phospholipid binding; protein kinase C binding; protein domain specific binding.	0.600
GluRIIA	cora	FBpp0078739	FBpp0085697	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Protein 4.1 homolog; An integral component of the septate junction. May play a role in cell-cell interactions that are necessary for proper development. Vital for embryonic development.	0.600
GluRIIB	GluRIIA	FBpp0088541	FBpp0078739	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.948
GluRIIB	GluRIIC	FBpp0088541	FBpp0307912	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission.	0.914
GluRIIB	GluRIID	FBpp0088541	FBpp0083346	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.987
GluRIIB	GluRIIE	FBpp0088541	FBpp0110134	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport.	0.986
GluRIIC	GluRIIA	FBpp0307912	FBpp0078739	Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission.	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.835
GluRIIC	GluRIIB	FBpp0307912	FBpp0088541	Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission.	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.914
GluRIIC	GluRIID	FBpp0307912	FBpp0083346	Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission.	Glutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.993
GluRIIC	GluRIIE	FBpp0307912	FBpp0110134	Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission.	Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport.	0.995
GluRIID	GluRIIA	FBpp0083346	FBpp0078739	Glutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.898
GluRIID	GluRIIB	FBpp0083346	FBpp0088541	Glutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.987
GluRIID	GluRIIC	FBpp0083346	FBpp0307912	Glutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission.	0.993
GluRIID	GluRIIE	FBpp0083346	FBpp0110134	Glutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport.	0.996
GluRIIE	GluRIIA	FBpp0110134	FBpp0078739	Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport.	Glutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.896
GluRIIE	GluRIIB	FBpp0110134	FBpp0088541	Glutamate receptor IIE (GluRIIE) encodes an ion channel subunit involved in calcium ion transport.	Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.	0.986