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GstO3 GstO3 eIF4E3 eIF4E3 Cyp4ac3 Cyp4ac3 GluRIIA GluRIIA obst-B obst-B CG4511 CG4511 GluRIID GluRIID Cpr49Ad Cpr49Ad DopEcR DopEcR GluRIIC GluRIIC mthl3 mthl3 Tsp42Ed Tsp42Ed
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
GstO3Glutathione S-transferase omega class; Glutathione S transferase O3 (GstO3) encodes a transferase involved in glutathione metabolism; Belongs to the GST superfamily. (241 aa)
eIF4E3Eukaryotic translation initiation factor 4E3 (eIF4E3) encodes a protein that binds the 7-methyl-guanosine cap structure of mRNA. It is a component of the eIF4F cap-binding complex that is essential for cap-dependent translation of mRNA. eIF4E3 is primarily expressed in testes and is required for male fertility, but not for viability. (244 aa)
Cyp4ac3Probable cytochrome P450 4ac3; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (509 aa)
GluRIIAGlutamate receptor IIA (GluRIIA) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (907 aa)
obst-BBcDNA.GH02976; Chitin binding. It is involved in the biological process described with: chitin metabolic process. (337 aa)
CG4511GM03430p. (216 aa)
GluRIIDGlutamate receptor IID (GluRIID) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. (902 aa)
Cpr49AdCuticular protein 49Ad; Structural constituent of cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development. (166 aa)
DopEcRDopamine/Ecdysteroid receptor (DopEcR) encodes a GPCR that shows ligand-biased activation. It can be activated by dopamine to increase cyclic AMP levels and by the insect steroid ecdysone to activate the MAPKinase pathway. It is widely expressed in the nervous system and can modulate a wide variety of complex behaviors including male courtship, locomotion, the response to stressful social interactions and the regulation of appetite. (322 aa)
GluRIICGlutamate receptor IIC (GluRIIC) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction. It is required for the synaptic localization of the products of GluRIIA and GluRIIB and for synaptic transmission. (940 aa)
mthl3Probable G-protein coupled receptor Mth-like 3; G protein-coupled receptor activity. It is involved in the biological process described with: determination of adult lifespan; cell surface receptor signaling pathway; G protein-coupled receptor signaling pathway; response to starvation. (511 aa)
Tsp42EdTetraspanin. (227 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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