STRINGSTRING
Hexo2 Hexo2 Hex-A Hex-A Hexo1 Hexo1 zld zld Hex-t1 Hex-t1 Hex-t2 Hex-t2 eEF1alpha2 eEF1alpha2 Hex-C Hex-C eEF1alpha1 eEF1alpha1 vri vri
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hexo2Beta-hexosaminidase; Hexosaminidase 2 (Hexo2) encodes a beta-N-acetylglucosaminidase involved in carbohydrate metabolism. (622 aa)
Hex-APhosphotransferase; Hexokinase A (Hex-A) encodes a hexokinase involved in glucose homeostasis. (541 aa)
Hexo1Beta-hexosaminidase; Hexosaminidase 1 (Hexo1) encodes a beta-N-acetylglucosaminidase involved in protein deglycosylation and rhodopsin biosynthesis. (622 aa)
zldZelda, isoform A; Zelda (zld) encodes a zinc finger transcription factor that functions in early blastoderm development. It works as a zygotic genome activator because it has a global role in regulating early expressed genes, such as genes essential for cellularization, sex determination and pattern formation. It is also required at later times in development. (1596 aa)
Hex-t1Hexokinase type 1; Catalyzes the phosphorylation of various hexoses to hexose 6- phosphate. (465 aa)
Hex-t2Hexokinase type 2; Catalyzes the phosphorylation of various hexoses to hexose 6- phosphate. (486 aa)
eEF1alpha2Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (462 aa)
Hex-CPhosphotransferase; Hexokinase C (Hex-C) encodes a hexokinase involved in glucose homeostasis. (454 aa)
eEF1alpha1Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (463 aa)
vriVrille, isoform A; Vrille (vri) encodes a bZIP transcription factor acting as an enhancer of dpp phenotypes both in embryo and in wing. It is involved in hair and cell growth and in tracheal development. Vri is a clock-controlled gene acting as a repressor of the products of Clk and cry. (729 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.