STRINGSTRING
S-Lap4 S-Lap4 S-Lap1 S-Lap1 S-Lap2 S-Lap2 ProtB ProtB ProtA ProtA ms(3)K81 ms(3)K81 Mst98Cb Mst98Cb betaTub56D betaTub56D S-Lap8 S-Lap8 S-Lap5 S-Lap5 S-Lap7 S-Lap7 sw sw Sdic1 Sdic1 loopin-1 loopin-1 Tlk Tlk AnxB10 AnxB10 S-Lap3 S-Lap3 grsm grsm Sdic2 Sdic2 Sdic3 Sdic3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
S-Lap4Sperm-Leucylaminopeptidase 4; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis. (524 aa)
S-Lap1Sperm-Leucylaminopeptidase 1; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: mushroom body development; proteolysis. (555 aa)
S-Lap2Sperm-Leucylaminopeptidase 2; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis. (552 aa)
ProtBProtamine B (ProtB) encodes a protamine protein involved in packaging the paternal genome in sperm. Protamines are small highly basic proteins with numerous cysteines. (144 aa)
ProtAProtamine A (ProtA) encodes a protamine protein involved in packaging the paternal genome in sperm. Protamines are small highly basic proteins with numerous cysteines. (146 aa)
ms(3)K81Male sterile (3) K81 (ms(3)K81) encodes a telomere capping protein that is required to protect sperm telomeres from end-to-end fusion at fertilization. The ms(3)K81 product replaces its paralog HipHop in post-meiotic male germ cell nuclei. (184 aa)
Mst98CbMale-specific RNA 98Cb; It is involved in the biological process described with: spermatid development. (265 aa)
betaTub56DTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (456 aa)
S-Lap8Sperm-Leucylaminopeptidase 8; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis. (534 aa)
S-Lap5Sperm-Leucylaminopeptidase 5; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis; mesoderm development. (549 aa)
S-Lap7Sperm-Leucylaminopeptidase 7, isoform A; Manganese ion binding; metalloexopeptidase activity; aminopeptidase activity. It is involved in the biological process described with: proteolysis; multicellular organism reproduction. (527 aa)
swCytoplasmic dynein 1 intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the help dynein bind to dynactin 150 kDa component (By similarity). (663 aa)
Sdic1Sperm-specific dynein intermediate chain 1, isoform A; Dynein light chain binding; dynein heavy chain binding. It is involved in the biological process described with: positive regulation of ATP-dependent microtubule motor activity, plus-end-directed; microtubule-based movement. (517 aa)
loopin-1Loopin-1, isoform A; Loopin-1 (loopin-1) encodes a testis-specific protein with homology to several leucine aminopeptidases. Sequence analysis suggest that it doesn't have enzymatic activity. It accumulates inside the axoneme-associated mitochondrial derivative in mature sperms. (526 aa)
TlkTousled-like kinase, isoform G; Tousled-like kinase (Tlk) encodes a serine/threonine kinase that acts in a cell cycle-dependent manner. It contributes to cell morphogenesis, cell migration and cell death through interactions with chromatin components. (1489 aa)
AnxB10Annexin B10 (AnxB10) encodes a calcium-dependent phospholipid binding protein; Belongs to the annexin family. (321 aa)
S-Lap3Sperm-Leucylaminopeptidase 3, isoform B; Manganese ion binding; metalloexopeptidase activity; aminopeptidase activity. It is involved in the biological process described with: proteolysis. (535 aa)
grsmGranny smith (grsm) encodes a member of the M17 family of leucine aminopeptidases, a family of proteases broadly involved in a number of cellular processes. High throughput transcriptomic and proteomic analyses have implicated the product of grsm in the regulation of immune-, nervous- and immune-related processes. (655 aa)
Sdic2Sperm-specific dynein intermediate chain 2, isoform A; Dynein light chain binding; dynein heavy chain binding. It is involved in the biological process described with: positive regulation of ATP-dependent microtubule motor activity, plus-end-directed; microtubule-based movement. (543 aa)
Sdic3Sperm-specific dynein intermediate chain 3, isoform E; It is involved in the biological process described with: microtubule-based movement. (533 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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