node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG1637 | CG44085 | FBpp0308868 | FBpp0306886 | Acid phosphatase activity; metal ion binding. | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | 0.676 |
CG1637 | mtd | FBpp0308868 | FBpp0297633 | Acid phosphatase activity; metal ion binding. | Mustard, isoform V; Mustard (mtd) encodes an ecdysone-regulated late puff protein. A isoform including only the C-terminal with a TLDc domain enters the nucleus. This isoform increases intestinal stem cell division and suppresses expression of the antimicrobial peptide encoded by DptA at the transcriptional level, independent of IMD pathway signaling. | 0.400 |
CG44085 | CG1637 | FBpp0306886 | FBpp0308868 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | Acid phosphatase activity; metal ion binding. | 0.676 |
CG44085 | Doa | FBpp0306886 | FBpp0289029 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | 0.631 |
CG44085 | Pdp1 | FBpp0306886 | FBpp0076495 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | PAR-domain protein 1 (Pdp1) encodes a member of the PAR domain bZip family of sequence-specific transcription factors. it regulates gene expression in muscles and in circadian clock neurons. | 0.462 |
CG44085 | SNF4Agamma | FBpp0306886 | FBpp0290803 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | SNF4/AMP-activated protein kinase gamma subunit (SNF4Agamma) encodes a protein involved in lipid metabolism, autophagy and response to starvation. | 0.515 |
CG44085 | Zasp52 | FBpp0306886 | FBpp0099801 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | Z band alternatively spliced PDZ-motif protein 52 (Zasp52) encodes a member of the Zasp protein family. It is a scaffold protein that binds the product of Actn and localizes to muscle attachment sites and Z-discs in muscle cells, as well as localizing cortically in non-muscle cells. It plays a role in muscle development, especially in myofibril assembly. | 0.596 |
CG44085 | bbc | FBpp0306886 | FBpp0086818 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | Bb in a boxcar, isoform B; Diacylglycerol cholinephosphotransferase activity; ethanolaminephosphotransferase activity; phosphotransferase activity, for other substituted phosphate groups. It is involved in the biological process described with: phosphatidylethanolamine biosynthetic process; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.665 |
CG44085 | heph | FBpp0306886 | FBpp0297632 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | Hephaestus, isoform Y; Hephaestus (heph) encodes a nucleo-cytoplasmic shuttling protein that regulates osk mRNA translation. It is involved in spermatid individualization and Notch signalling regulation. | 0.495 |
CG44085 | mtd | FBpp0306886 | FBpp0297633 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | Mustard, isoform V; Mustard (mtd) encodes an ecdysone-regulated late puff protein. A isoform including only the C-terminal with a TLDc domain enters the nucleus. This isoform increases intestinal stem cell division and suppresses expression of the antimicrobial peptide encoded by DptA at the transcriptional level, independent of IMD pathway signaling. | 0.671 |
CG44085 | par-1 | FBpp0306886 | FBpp0303278 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | Par-1 (par-1) encodes a protein kinase involved in multiple processes, including microtubule cytoskeleton organization, axis specification and cell polarity. It regulates hippo signaling and osk mRNA localization. | 0.492 |
CG44085 | sdt | FBpp0306886 | FBpp0111740 | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | Stardust, isoform G; Stardust (sdt) encodes membrane-associated guanylate kinase (MAGUK) protein involved in the maintenance of apico-basal cell polarity and the organization of zonula adherens; Belongs to the MAGUK family. | 0.468 |
Doa | CG44085 | FBpp0289029 | FBpp0306886 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | Uncharacterized protein, isoform O; MAP-kinase scaffold activity. | 0.631 |
Doa | Imp | FBpp0289029 | FBpp0293680 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | 0.430 |
Doa | Prp8 | FBpp0289029 | FBpp0087124 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | pre-mRNA processing factor 8 (Prp8) is an essential gene that encodes the largest and most highly conserved splicing factor. It is a core component of the U5 snRNP, with a key function in pre-mRNA processing catalyzed by the spliceosome. | 0.493 |
Doa | SNF4Agamma | FBpp0289029 | FBpp0290803 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | SNF4/AMP-activated protein kinase gamma subunit (SNF4Agamma) encodes a protein involved in lipid metabolism, autophagy and response to starvation. | 0.435 |
Doa | Zasp52 | FBpp0289029 | FBpp0099801 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | Z band alternatively spliced PDZ-motif protein 52 (Zasp52) encodes a member of the Zasp protein family. It is a scaffold protein that binds the product of Actn and localizes to muscle attachment sites and Z-discs in muscle cells, as well as localizing cortically in non-muscle cells. It plays a role in muscle development, especially in myofibril assembly. | 0.481 |
Doa | mtd | FBpp0289029 | FBpp0297633 | Serine/threonine-protein kinase Doa; Negative regulator of the copia retrotransposon element of the white (w) gene. In the eye, it is required for normal pigmentation, photoreceptor cell development and for organization of interommatidial bristles. Also essential for embryonic segmentation and differentiation of the nervous system. Functions in the control of alternative splicing by phosphorylating the arginine/serine-rich splicing factors, SR proteins; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. | Mustard, isoform V; Mustard (mtd) encodes an ecdysone-regulated late puff protein. A isoform including only the C-terminal with a TLDc domain enters the nucleus. This isoform increases intestinal stem cell division and suppresses expression of the antimicrobial peptide encoded by DptA at the transcriptional level, independent of IMD pathway signaling. | 0.606 |
Dro | Drsl1 | FBpp0301076 | FBpp0072943 | Drosocin (Dro) encodes an o-Glycosylated antibacterial peptide with activity against Gram-negative and Gram-positive bacteria. It is expressed in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Dro is regulated at the transcriptional level mostly by the immune deficiency pathway; Belongs to the drosocin family. | Drosomycin-like C1; It is involved in the biological process described with: defense response to fungus. | 0.614 |
Dro | Drsl2 | FBpp0301076 | FBpp0072923 | Drosocin (Dro) encodes an o-Glycosylated antibacterial peptide with activity against Gram-negative and Gram-positive bacteria. It is expressed in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Dro is regulated at the transcriptional level mostly by the immune deficiency pathway; Belongs to the drosocin family. | Drosomycin-like 2 (Drsl2) encodes a secreted peptide with homology to the antifungal peptide encoded by Drs. | 0.604 |