node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACC | CG17191 | FBpp0087947 | FBpp0084522 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | RE51539p; Lipase activity; phospholipase A1 activity. It is involved in the biological process described with: lipid catabolic process. | 0.499 |
ACC | CG4797 | FBpp0087947 | FBpp0072148 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | RH09188p; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import. | 0.430 |
ACC | Eno | FBpp0087947 | FBpp0077572 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. | 0.428 |
ACC | FASN1 | FBpp0087947 | FBpp0307371 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Fatty acid synthase 1 (FASN1) encodes a fatty acid synthase involved in glycogen metabolism and triglyceride biosynthesis. | 0.992 |
ACC | Lip3 | FBpp0087947 | FBpp0082239 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Lipase 3; Hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process; Belongs to the AB hydrolase superfamily. Lipase family. | 0.569 |
ACC | Pdk | FBpp0087947 | FBpp0111805 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | [Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial; Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism; Belongs to the PDK/BCKDK protein kinase family. | 0.409 |
ACC | Pgi | FBpp0087947 | FBpp0087760 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. | 0.559 |
ACC | PyK | FBpp0087947 | FBpp0083611 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family. | 0.584 |
ACC | Tps1 | FBpp0087947 | FBpp0077121 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Trehalose-6-phosphate synthase 1 (Tps1) encodes the trehalose synthesis enzyme with an N-terminal trehalose-6-phosphate (T6P) synthase domain that catalyzes the production of T6P using glucose-6-phosphate and UDP-glucose. Its C-terminal T6P phosphatase domain dephosphorylates T6P to generate trehalose. | 0.487 |
ACC | whd | FBpp0087947 | FBpp0290497 | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | Withered (whd) encodes a carnitine O-palmitoyltransferase involved in oxidative stress. | 0.609 |
CG17191 | ACC | FBpp0084522 | FBpp0087947 | RE51539p; Lipase activity; phospholipase A1 activity. It is involved in the biological process described with: lipid catabolic process. | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | 0.499 |
CG17191 | CG4797 | FBpp0084522 | FBpp0072148 | RE51539p; Lipase activity; phospholipase A1 activity. It is involved in the biological process described with: lipid catabolic process. | RH09188p; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import. | 0.799 |
CG17191 | Lip3 | FBpp0084522 | FBpp0082239 | RE51539p; Lipase activity; phospholipase A1 activity. It is involved in the biological process described with: lipid catabolic process. | Lipase 3; Hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process; Belongs to the AB hydrolase superfamily. Lipase family. | 0.639 |
CG17191 | PyK | FBpp0084522 | FBpp0083611 | RE51539p; Lipase activity; phospholipase A1 activity. It is involved in the biological process described with: lipid catabolic process. | Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family. | 0.430 |
CG17191 | Tps1 | FBpp0084522 | FBpp0077121 | RE51539p; Lipase activity; phospholipase A1 activity. It is involved in the biological process described with: lipid catabolic process. | Trehalose-6-phosphate synthase 1 (Tps1) encodes the trehalose synthesis enzyme with an N-terminal trehalose-6-phosphate (T6P) synthase domain that catalyzes the production of T6P using glucose-6-phosphate and UDP-glucose. Its C-terminal T6P phosphatase domain dephosphorylates T6P to generate trehalose. | 0.443 |
CG4797 | ACC | FBpp0072148 | FBpp0087947 | RH09188p; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import. | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | 0.430 |
CG4797 | CG17191 | FBpp0072148 | FBpp0084522 | RH09188p; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import. | RE51539p; Lipase activity; phospholipase A1 activity. It is involved in the biological process described with: lipid catabolic process. | 0.799 |
CG4797 | Lip3 | FBpp0072148 | FBpp0082239 | RH09188p; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import. | Lipase 3; Hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process; Belongs to the AB hydrolase superfamily. Lipase family. | 0.495 |
CG4797 | Pgm1 | FBpp0072148 | FBpp0075247 | RH09188p; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import. | Phosphoglucomutase; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family. | 0.410 |
Eno | ACC | FBpp0077572 | FBpp0087947 | Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. | Acetyl-CoA carboxylase (ACC) encodes a ubiquitous metabolic enzyme. It catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting substrate for fatty acid synthesis. It is essential in the embryo and in the oenocytes (specialized abdominal cells) for the watertightness of the respiratory system. It is required in the fat body for triglyceride storage and in the muscles for locomotor activity. | 0.428 |