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Fbp1 Fbp1 Ilp3 Ilp3 ry ry InR InR Obp99c Obp99c RpL32 RpL32 NiPp1 NiPp1 Obp99b Obp99b Yp2 Yp2 Jon25Bii Jon25Bii Yp1 Yp1 Yp3 Yp3 Ilp5 Ilp5 Ilp6 Ilp6 Lsp1alpha Lsp1alpha rpr rpr grim grim
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fbp1Fat-body protein 1. (1029 aa)
Ilp3Insulin-like peptide 3 (Ilp3) encodes a peptide involved in the insulin signaling pathway, the sugar-mediated activation of TOR signaling, sleep and mating behavior in females. (120 aa)
ryXanthine dehydrogenase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid (By similarity). (1335 aa)
InRInsulin-like receptor subunit beta 1; Has a ligand-stimulated tyrosine-protein kinase activity. Required for cell survival. Regulates body size and organ size by altering cell number and cell size in a cell-autonomous manner. Involved in the development of the embryonic nervous system, and is necessary for axon guidance and targeting in the visual system. Also plays a role in life-span determination. (2144 aa)
Obp99cOdorant-binding protein 99c, isoform A; Odorant binding. It is involved in the biological process described with: response to fungus; sensory perception of smell; sensory perception of chemical stimulus. (151 aa)
RpL3260S ribosomal protein L32; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. (147 aa)
NiPp1Nuclear inhibitor of Protein phosphatase 1 (NiPp1) encodes a PP1 phosphatase inhibitor involved in axon guidance. (383 aa)
Obp99bGeneral odorant-binding protein 99b; Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid. (149 aa)
Yp2Vitellogenin-2; Vitellogenin is the major yolk protein of eggs where it is used as a food source during embryogenesis; Belongs to the AB hydrolase superfamily. Lipase family. (442 aa)
Jon25BiiJonah 25Bii, isoform A; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. (276 aa)
Yp1Vitellogenin-1; Vitellogenin is the major yolk protein of eggs where it is used as a food source during embryogenesis; Belongs to the AB hydrolase superfamily. Lipase family. (439 aa)
Yp3Vitellogenin-3; Vitellogenin is the major yolk protein of eggs where it is used as a food source during embryogenesis; Belongs to the AB hydrolase superfamily. Lipase family. (420 aa)
Ilp5Insulin-like peptide 5 (Ilp5) encodes a peptide involved in the insulin signaling pathway, sleep and mating behavior in females; Belongs to the insulin family. (108 aa)
Ilp6Insulin-like peptide 6 (Ilp6) encodes a protein that promotes growth during starvation. (107 aa)
Lsp1alphaLarval serum protein 1 alpha chain; Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins; Belongs to the hemocyanin family. (816 aa)
rprCell death protein rpr; Reaper (rpr) encodes Reaper, Hid, Grim (RHG) protein. It contributes to the caspase dependent apoptosis by inhibiting the anti-apoptotic protein encoded by Diap1. (65 aa)
grimCell death protein Grim; Grim (grim) encodes a member of the inhibitor of apoptotic protein antagonists. In response to death signals, it induces apoptosis of cells in the central nervous system. It is important particularly for the apoptosis of specific juvenile neurons during metamorphosis. (138 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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