(20 nodes) (2014) Sex pheromone biosynthetic pathways are conserved between moths and the butterfly Bicyclus anynana. network (Drosophila melanogaster)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	CG10097	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (501 aa)
	Sgp	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (523 aa)
	CG1441	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (517 aa)
	CG12268	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (531 aa)
	CG14893	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (510 aa)
	CG10096	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (502 aa)
	CG34342	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (572 aa)
	CG4020	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (494 aa)
	His3:CG31613	Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
	CG9747	GH07782p; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (461 aa)
	FarO	Fatty acyl-CoA reductase in oenocytes (FarO) encodes a long-chain-fatty-acyl-CoA reductase involved in the regulation of cell growth and lipid storage. (504 aa)
	CG30427	CG30427 encodes a fatty-acyl-CoA reductase involved in production of NADPH, sensory perception of pain, phagocytosis and determination of lifespan. (506 aa)
	Fad2	Fad2 (Fad2) encodes a transmembrane fatty acid desaturase that utilizes mono-unsaturated long-chain fatty acids (LCFAs) to synthesize di-unsaturated LCFAs. It is involved in the synthesis of the female pheromones. (355 aa)
	Trp1	Translocation protein 1, isoform B; Protein transmembrane transporter activity. It is involved in the biological process described with: posttranslational protein targeting to membrane, translocation. (428 aa)
	Desat1	Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids. (383 aa)
	CG17562	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (499 aa)
	CG17560	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (499 aa)
	CG4770	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (490 aa)
	CG9743	RH14937p; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (420 aa)
	CG15531	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (334 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG10096	Desat1	FBpp0312435	FBpp0082096	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids.	0.498
CG10096	Sgp	FBpp0312435	FBpp0305607	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.451
CG10097	CG15531	FBpp0312436	FBpp0084938	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	0.404
CG10097	Desat1	FBpp0312436	FBpp0082096	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids.	0.605
CG10097	Fad2	FBpp0312436	FBpp0075926	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Fad2 (Fad2) encodes a transmembrane fatty acid desaturase that utilizes mono-unsaturated long-chain fatty acids (LCFAs) to synthesize di-unsaturated LCFAs. It is involved in the synthesis of the female pheromones.	0.497
CG12268	Desat1	FBpp0300414	FBpp0082096	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids.	0.495
CG1441	Desat1	FBpp0087533	FBpp0082096	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids.	0.493
CG14893	Desat1	FBpp0290087	FBpp0082096	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids.	0.500
CG15531	CG10097	FBpp0084938	FBpp0312436	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.404
CG15531	CG17560	FBpp0084938	FBpp0082780	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.651
CG15531	CG17562	FBpp0084938	FBpp0082779	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.875
CG15531	CG4020	FBpp0084938	FBpp0305934	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.837
CG15531	FarO	FBpp0084938	FBpp0070407	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	Fatty acyl-CoA reductase in oenocytes (FarO) encodes a long-chain-fatty-acyl-CoA reductase involved in the regulation of cell growth and lipid storage.	0.832
CG15531	Sgp	FBpp0084938	FBpp0305607	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.440
CG17560	CG15531	FBpp0082780	FBpp0084938	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	0.651
CG17560	CG17562	FBpp0082780	FBpp0082779	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.802
CG17560	CG4020	FBpp0082780	FBpp0305934	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.479
CG17560	Desat1	FBpp0082780	FBpp0082096	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids.	0.496
CG17560	Sgp	FBpp0082780	FBpp0305607	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	0.405
CG17562	CG15531	FBpp0082779	FBpp0084938	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.	FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family.	0.875