node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Brd | E(spl)m6-BFM | FBpp0075374 | FBpp0084333 | Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification. | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | 0.659 |
Brd | E(spl)m7-HLH | FBpp0075374 | FBpp0084334 | Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification. | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | 0.716 |
Brd | E(spl)m8-HLH | FBpp0075374 | FBpp0084335 | Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification. | Enhancer of split m8 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. Part of the Notch signaling pathway. | 0.824 |
Brd | FBgn0002734 | FBpp0075374 | FBpp0084328 | Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification. | Enhancer of split mdelta protein; Transcriptional repressor of genes that require a bHLH protein for their transcription (By similarity). May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes. Contributes to the neural-epidermal lineage decision during early neurogenesis. As part of the Notch signaling pathway, required to maintain the self-renewal and identity of type II neuroblasts by regulating the expression of the transcriptional repressor erm. | 0.887 |
Brd | FBgn0002735 | FBpp0075374 | FBpp0084329 | Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification. | Enhancer of split mgamma protein; Transcriptional repressor of genes that require a bHLH protein for their transcription. May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes. Contributes to the neural-epidermal lineage decision during early neurogenesis. Part of the Notch signaling pathway, plays a role in neuroblasts proliferation in embryos and larvae. In the larval brain, together with other self-renewal transcriptional repressors such as klu and dpn, required for type II neuroblast self-renewal and for maintaining erm in an inactive state in intermedi [...] | 0.930 |
Brd | Sply | FBpp0075374 | FBpp0086158 | Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification. | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | 0.837 |
E(spl)m6-BFM | Brd | FBpp0084333 | FBpp0075374 | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification. | 0.659 |
E(spl)m6-BFM | E(spl)m7-HLH | FBpp0084333 | FBpp0084334 | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | 0.685 |
E(spl)m6-BFM | E(spl)m8-HLH | FBpp0084333 | FBpp0084335 | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | Enhancer of split m8 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. Part of the Notch signaling pathway. | 0.550 |
E(spl)m6-BFM | FBgn0002734 | FBpp0084333 | FBpp0084328 | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | Enhancer of split mdelta protein; Transcriptional repressor of genes that require a bHLH protein for their transcription (By similarity). May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes. Contributes to the neural-epidermal lineage decision during early neurogenesis. As part of the Notch signaling pathway, required to maintain the self-renewal and identity of type II neuroblasts by regulating the expression of the transcriptional repressor erm. | 0.534 |
E(spl)m6-BFM | FBgn0002735 | FBpp0084333 | FBpp0084329 | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | Enhancer of split mgamma protein; Transcriptional repressor of genes that require a bHLH protein for their transcription. May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes. Contributes to the neural-epidermal lineage decision during early neurogenesis. Part of the Notch signaling pathway, plays a role in neuroblasts proliferation in embryos and larvae. In the larval brain, together with other self-renewal transcriptional repressors such as klu and dpn, required for type II neuroblast self-renewal and for maintaining erm in an inactive state in intermedi [...] | 0.445 |
E(spl)m6-BFM | Kaz-m1 | FBpp0084333 | FBpp0301783 | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | Enhancer of split M1 protein; Serine-type endopeptidase inhibitor activity. | 0.678 |
E(spl)m6-BFM | Sply | FBpp0084333 | FBpp0086158 | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | 0.669 |
E(spl)m7-HLH | Brd | FBpp0084334 | FBpp0075374 | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | Bearded (Brd) encodes a member of the Bearded family, which are small proteins containing predicted basic amphipathic alpha-helical domains in their N-terminal regions. The product of Brd is involved in Notch signaling pathway regulation and cell fate specification. | 0.716 |
E(spl)m7-HLH | E(spl)m6-BFM | FBpp0084334 | FBpp0084333 | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | Enhancer of split m6 protein; Ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; sensory organ development; cell fate specification. | 0.685 |
E(spl)m7-HLH | E(spl)m8-HLH | FBpp0084334 | FBpp0084335 | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | Enhancer of split m8 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. Part of the Notch signaling pathway. | 0.939 |
E(spl)m7-HLH | FBgn0002734 | FBpp0084334 | FBpp0084328 | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | Enhancer of split mdelta protein; Transcriptional repressor of genes that require a bHLH protein for their transcription (By similarity). May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes. Contributes to the neural-epidermal lineage decision during early neurogenesis. As part of the Notch signaling pathway, required to maintain the self-renewal and identity of type II neuroblasts by regulating the expression of the transcriptional repressor erm. | 0.973 |
E(spl)m7-HLH | FBgn0002735 | FBpp0084334 | FBpp0084329 | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | Enhancer of split mgamma protein; Transcriptional repressor of genes that require a bHLH protein for their transcription. May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes. Contributes to the neural-epidermal lineage decision during early neurogenesis. Part of the Notch signaling pathway, plays a role in neuroblasts proliferation in embryos and larvae. In the larval brain, together with other self-renewal transcriptional repressors such as klu and dpn, required for type II neuroblast self-renewal and for maintaining erm in an inactive state in intermedi [...] | 0.954 |
E(spl)m7-HLH | Kaz-m1 | FBpp0084334 | FBpp0301783 | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | Enhancer of split M1 protein; Serine-type endopeptidase inhibitor activity. | 0.465 |
E(spl)m7-HLH | Sply | FBpp0084334 | FBpp0086158 | Enhancer of split m7 protein; Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'. | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | 0.836 |