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Cyp4g1 Cyp4g1 AstA-R1 AstA-R1 Mdr65 Mdr65 ninaC ninaC GCS2beta GCS2beta CG17568 CG17568 dtr dtr CRAT CRAT CG31495 CG31495 Cyp6a2 Cyp6a2 Mdr50 Mdr50 Mdr49 Mdr49 sut1 sut1 Cyp12d1-d Cyp12d1-d MRP MRP ref(2)P ref(2)P l(2)05287 l(2)05287 CG42329 CG42329 CG31612 CG31612 Dscam1 Dscam1 Mnt Mnt CG15394 CG15394 RtGEF RtGEF Cyp6g1 Cyp6g1 Cyp12d1-p Cyp12d1-p CG8677 CG8677 fd3F fd3F
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene fusions
gene co-occurrence
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Cyp4g1Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes. (556 aa)
AstA-R1Allatostatin A receptor 1 (AstA-R1) encodes a G-protein coupled receptor for the neuropeptide encoded by AstA. (394 aa)
Mdr65Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. (1302 aa)
ninaCNeither inactivation nor afterpotential protein C; Required for photoreceptor cell function. The ninaC proteins combines putative serine/threonine-protein kinase and myosin activities. Essential for the expression and stability of the rtp protein in the photoreceptors. The rtp/ninaC complex is required for stability of inad and inac and the normal termination of phototransduction in the retina. (1501 aa)
GCS2betaGlucosidase 2 beta subunit, isoform A; It is involved in the biological process described with: N-glycan processing. (548 aa)
CG17568IP01252p; Zinc ion binding; nucleic acid binding; transcription corepressor activity. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II. (513 aa)
dtrDynein assembly factor 1, axonemal homolog; Cilium-specific protein required for cilia structures. Belongs to the DNAAF1 family. (1483 aa)
CRATCarnitine O-acetyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; carnitine metabolic process, CoA-linked; Belongs to the carnitine/choline acetyltransferase family. (662 aa)
CG31495RE10813p; ATPase activity; ATP binding. It is involved in the biological process described with: intra-Golgi vesicle-mediated transport; Golgi vesicle docking; Golgi to plasma membrane protein transport; SNARE complex disassembly. (341 aa)
Cyp6a2Cytochrome P450 6a2; Is involved in the breakdown of synthetic insecticides and may be involved in the metabolism of insect hormones. (506 aa)
Mdr50Multi drug resistance 50; Efflux transmembrane transporter activity; ATPase-coupled xenobiotic transmembrane transporter activity; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: response to insecticide; response to toxic substance; xenobiotic transport; transmembrane transport; renal tubular secretion. (1313 aa)
Mdr49Multidrug resistance protein homolog 49; Multi drug resistance 49 (Mdr49) encodes drug transmembrane transporter that belongs to the ABCB transporter subfamily and contributes to insecticide resistance. (1302 aa)
sut1Sugar transporter 1; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa)
Cyp12d1-dProbable cytochrome P450 12d1 distal, mitochondrial; Cyp12d1-d (Cyp12d1-d) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT). (521 aa)
MRPMultidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport. (1549 aa)
ref(2)PProtein ref(2)P; Required for selective autophagy activation by ubiquitinated proteins. Implicated in sigma rhabdovirus multiplication and necessary for male fertility. Involved in activating transcription of Drs. (599 aa)
l(2)05287Lethal (2) 05287. (1071 aa)
CG42329NRF domain-containing protein; Transferase activity, transferring acyl groups other than amino-acyl groups. (691 aa)
CG31612IP01335p; Sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: positive regulation of nuclear cell cycle DNA replication; regulation of transcription by RNA polymerase II. (987 aa)
Dscam1Down syndrome cell adhesion molecule 1, isoform BX; Identical protein binding; antigen binding; protein homodimerization activity; axon guidance receptor activity; cell-cell adhesion mediator activity. (2038 aa)
MntMnt, isoform I; Mnt (Mnt) encodes a protein that belongs to the basic-helic-loop-helix-zipper class of transcription factors, which form heterodimers with the protein encoded by Max. Mnt product acts as a repressor of transcription by recruiting a co-repressor complex to its genomic binding sites. It antagonizes cell growth promoting functions of the product encoded by Myc and its depletion produces flies with larger cells, increased weight, and decreased lifespan. (790 aa)
CG15394Uncharacterized protein, isoform C. (159 aa)
RtGEFRho-type guanine nucleotide exchange factor (RtGEF) encodes a putative Rho-type guanine nucleotide exchange factor for the GTPases encoded by Rac1 and Cdc42. It signals through the sterile-20 kinases encoded by Pak and hpo. The product of RtGEF contributes to regulation of postsynaptic structure, post synaptic muscle development, protein localization and the growth of epithelial tissue. (1310 aa)
Cyp6g1Cytochrome P450 6g1; Necessary and sufficient for resistance to insecticides DDT and imidacloprid. May be involved in the metabolism of insect hormones. (524 aa)
Cyp12d1-pProbable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT). (521 aa)
CG8677Uncharacterized protein, isoform B; CG8677 encodes a protein that dimerizes with the product of Iswi to form a chromatin remodeling factor RSF (remodeling and spacing factor). RSF is involved in silent chromatin formation via replacement of the product of His2Av. (2663 aa)
fd3FForkhead domain 3F (fd3F) encodes a trancription factor that contributes to the specialization of mechanosensory cilium. (764 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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