node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Antp | caup | FBpp0081162 | FBpp0075641 | Homeotic protein antennapedia; Antennapedia (Antp) is the distal-most member of the Antennapedia complex; one of two Hox gene complexes. Antp encodes a sequence-specific homeodomain transcription factor, which is part of a developmental regulatory system that specifies segmental identity in the pro- and mesothorax. In adults Antp loss of function is associated with a transformation of leg into antenna while ectopic expression in the head is associated with antenna to leg and eye to wing transformations. | Homeobox protein caupolican; Caupolican (caup) encodes a homeodomain-containing protein of the TALE subfamily and one of the three components of the Iroquois gene complex. caup product acts as a transcriptional regulator to control territorial and cell fate specification, cell sorting behaviour and pattern formation. It also plays a transcription independent cell-autonomous role in cell proliferation control. | 0.526 |
Sply | ac | FBpp0086158 | FBpp0070071 | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | 0.791 |
Sply | ase | FBpp0086158 | FBpp0070074 | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | Achaete-scute complex protein T8; Asense (ase) encodes a transcription factor in the achaete-scute complex. It acts together with other proneural genes in nervous system development, which involves N-mediated lateral inhibition. ase is expressed in the CNS type-I neuroblasts and the PNS sensory organ precursors (SOPs) but not in the proneural clusters that give rise to the SOP via lateral inhibition. | 0.607 |
Sply | l(1)sc | FBpp0086158 | FBpp0070073 | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | Achaete-scute complex protein T3; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. | 0.545 |
Sply | sc | FBpp0086158 | FBpp0070072 | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | Achaete-scute complex protein T4; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Also involved in sex determination and dosage compensation. | 0.799 |
ac | Sply | FBpp0070071 | FBpp0086158 | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | 0.791 |
ac | ase | FBpp0070071 | FBpp0070074 | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | Achaete-scute complex protein T8; Asense (ase) encodes a transcription factor in the achaete-scute complex. It acts together with other proneural genes in nervous system development, which involves N-mediated lateral inhibition. ase is expressed in the CNS type-I neuroblasts and the PNS sensory organ precursors (SOPs) but not in the proneural clusters that give rise to the SOP via lateral inhibition. | 0.604 |
ac | caup | FBpp0070071 | FBpp0075641 | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | Homeobox protein caupolican; Caupolican (caup) encodes a homeodomain-containing protein of the TALE subfamily and one of the three components of the Iroquois gene complex. caup product acts as a transcriptional regulator to control territorial and cell fate specification, cell sorting behaviour and pattern formation. It also plays a transcription independent cell-autonomous role in cell proliferation control. | 0.450 |
ac | eve | FBpp0070071 | FBpp0087478 | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | Segmentation protein even-skipped; May play a role in determining neuronal identity. May be directly involved in specifying identity of individual neurons. Pair- rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes; Belongs to the even-skipped homeobox family. | 0.430 |
ac | l(1)sc | FBpp0070071 | FBpp0070073 | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | Achaete-scute complex protein T3; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. | 0.899 |
ac | sc | FBpp0070071 | FBpp0070072 | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | Achaete-scute complex protein T4; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Also involved in sex determination and dosage compensation. | 0.997 |
ase | Sply | FBpp0070074 | FBpp0086158 | Achaete-scute complex protein T8; Asense (ase) encodes a transcription factor in the achaete-scute complex. It acts together with other proneural genes in nervous system development, which involves N-mediated lateral inhibition. ase is expressed in the CNS type-I neuroblasts and the PNS sensory organ precursors (SOPs) but not in the proneural clusters that give rise to the SOP via lateral inhibition. | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Sphingolipid catabolism is required for normal development including viability, reproduction and muscle development. Belongs to the group II decarboxylase family. Sphingosine- 1-phosphate lyase subfamily. | 0.607 |
ase | ac | FBpp0070074 | FBpp0070071 | Achaete-scute complex protein T8; Asense (ase) encodes a transcription factor in the achaete-scute complex. It acts together with other proneural genes in nervous system development, which involves N-mediated lateral inhibition. ase is expressed in the CNS type-I neuroblasts and the PNS sensory organ precursors (SOPs) but not in the proneural clusters that give rise to the SOP via lateral inhibition. | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | 0.604 |
ase | l(1)sc | FBpp0070074 | FBpp0070073 | Achaete-scute complex protein T8; Asense (ase) encodes a transcription factor in the achaete-scute complex. It acts together with other proneural genes in nervous system development, which involves N-mediated lateral inhibition. ase is expressed in the CNS type-I neuroblasts and the PNS sensory organ precursors (SOPs) but not in the proneural clusters that give rise to the SOP via lateral inhibition. | Achaete-scute complex protein T3; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. | 0.690 |
ase | sc | FBpp0070074 | FBpp0070072 | Achaete-scute complex protein T8; Asense (ase) encodes a transcription factor in the achaete-scute complex. It acts together with other proneural genes in nervous system development, which involves N-mediated lateral inhibition. ase is expressed in the CNS type-I neuroblasts and the PNS sensory organ precursors (SOPs) but not in the proneural clusters that give rise to the SOP via lateral inhibition. | Achaete-scute complex protein T4; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Also involved in sex determination and dosage compensation. | 0.742 |
caup | Antp | FBpp0075641 | FBpp0081162 | Homeobox protein caupolican; Caupolican (caup) encodes a homeodomain-containing protein of the TALE subfamily and one of the three components of the Iroquois gene complex. caup product acts as a transcriptional regulator to control territorial and cell fate specification, cell sorting behaviour and pattern formation. It also plays a transcription independent cell-autonomous role in cell proliferation control. | Homeotic protein antennapedia; Antennapedia (Antp) is the distal-most member of the Antennapedia complex; one of two Hox gene complexes. Antp encodes a sequence-specific homeodomain transcription factor, which is part of a developmental regulatory system that specifies segmental identity in the pro- and mesothorax. In adults Antp loss of function is associated with a transformation of leg into antenna while ectopic expression in the head is associated with antenna to leg and eye to wing transformations. | 0.526 |
caup | ac | FBpp0075641 | FBpp0070071 | Homeobox protein caupolican; Caupolican (caup) encodes a homeodomain-containing protein of the TALE subfamily and one of the three components of the Iroquois gene complex. caup product acts as a transcriptional regulator to control territorial and cell fate specification, cell sorting behaviour and pattern formation. It also plays a transcription independent cell-autonomous role in cell proliferation control. | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | 0.450 |
caup | sc | FBpp0075641 | FBpp0070072 | Homeobox protein caupolican; Caupolican (caup) encodes a homeodomain-containing protein of the TALE subfamily and one of the three components of the Iroquois gene complex. caup product acts as a transcriptional regulator to control territorial and cell fate specification, cell sorting behaviour and pattern formation. It also plays a transcription independent cell-autonomous role in cell proliferation control. | Achaete-scute complex protein T4; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Also involved in sex determination and dosage compensation. | 0.501 |
eve | ac | FBpp0087478 | FBpp0070071 | Segmentation protein even-skipped; May play a role in determining neuronal identity. May be directly involved in specifying identity of individual neurons. Pair- rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes; Belongs to the even-skipped homeobox family. | Achaete-scute complex protein T5; Achaete (ac) encodes a BHLH transcription factor that interacts antagonistically with the Notch signaling pathway to promote neural precursor formation. Its major role is in nervous system development. | 0.430 |
eve | l(1)sc | FBpp0087478 | FBpp0070073 | Segmentation protein even-skipped; May play a role in determining neuronal identity. May be directly involved in specifying identity of individual neurons. Pair- rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes; Belongs to the even-skipped homeobox family. | Achaete-scute complex protein T3; AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. | 0.498 |