Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm.

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

I-kappaB kinase epsilon (IKKepsilon) encodes a serine-threonine kinase that targets the inhibitor of apoptosis encoded by Diap1 for degradation. It also negatively regulates protein kinase C and the dynein adaptor encoded nuf. The product of IKKepsilon contributes to the specification of bristle cells, bristle cell morphogenesis, oocyte polarity, and dendrite development.

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

LD14015p; It is involved in the biological process described with: protein transport; endosome transport via multivesicular body sorting pathway; protein localization.

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...]

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). Seems to function as a tumor suppressor by regulating Notch trafficking, hence preventing non-autonomous overproliferation. May be invo [...]

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

Vacuolar protein sorting 4 (Vps4) encodes an AAA family ATPase. It catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes. It functions in endosomal sorting of cargo into the multivesicular body for lysosomal degradation, abscission during cell division, virus release and nuclear envelope membrane sealing after cell division.

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

Apontic, isoform F; Apontic (apt) encodes a DNA-binding protein that acts as a transcriptional regulator and can function in translational repression. It plays roles in cell migration, cell fate specification, and morphogenesis via STAT signaling pathway inhibition.

Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm.

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm.

LD14015p; It is involved in the biological process described with: protein transport; endosome transport via multivesicular body sorting pathway; protein localization.

Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm.

Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). Seems to function as a tumor suppressor by regulating Notch trafficking, hence preventing non-autonomous overproliferation. May be invo [...]

Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm.

Vacuolar protein sorting 4 (Vps4) encodes an AAA family ATPase. It catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes. It functions in endosomal sorting of cargo into the multivesicular body for lysosomal degradation, abscission during cell division, virus release and nuclear envelope membrane sealing after cell division.

I-kappaB kinase epsilon (IKKepsilon) encodes a serine-threonine kinase that targets the inhibitor of apoptosis encoded by Diap1 for degradation. It also negatively regulates protein kinase C and the dynein adaptor encoded nuf. The product of IKKepsilon contributes to the specification of bristle cells, bristle cell morphogenesis, oocyte polarity, and dendrite development.

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

I-kappaB kinase epsilon (IKKepsilon) encodes a serine-threonine kinase that targets the inhibitor of apoptosis encoded by Diap1 for degradation. It also negatively regulates protein kinase C and the dynein adaptor encoded nuf. The product of IKKepsilon contributes to the specification of bristle cells, bristle cell morphogenesis, oocyte polarity, and dendrite development.

Apontic, isoform F; Apontic (apt) encodes a DNA-binding protein that acts as a transcriptional regulator and can function in translational repression. It plays roles in cell migration, cell fate specification, and morphogenesis via STAT signaling pathway inhibition.

LD14015p; It is involved in the biological process described with: protein transport; endosome transport via multivesicular body sorting pathway; protein localization.

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

LD14015p; It is involved in the biological process described with: protein transport; endosome transport via multivesicular body sorting pathway; protein localization.

Charged multivesicular body protein 1 (Chmp1) encodes a component of ESCRT-III, a conserved protein complex that mediates downregulation of activated transmembrane receptors through formation of the multivesicular body from the endosome. It binds to the product of Vps4, promoting the dissociation and recycling of ESCRT-III components to the cytoplasm.

LD14015p; It is involved in the biological process described with: protein transport; endosome transport via multivesicular body sorting pathway; protein localization.

Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). Seems to function as a tumor suppressor by regulating Notch trafficking, hence preventing non-autonomous overproliferation. May be invo [...]

LD14015p; It is involved in the biological process described with: protein transport; endosome transport via multivesicular body sorting pathway; protein localization.

Vacuolar protein sorting 4 (Vps4) encodes an AAA family ATPase. It catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes. It functions in endosomal sorting of cargo into the multivesicular body for lysosomal degradation, abscission during cell division, virus release and nuclear envelope membrane sealing after cell division.

Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...]

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.

Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...]

Apontic, isoform F; Apontic (apt) encodes a DNA-binding protein that acts as a transcriptional regulator and can function in translational repression. It plays roles in cell migration, cell fate specification, and morphogenesis via STAT signaling pathway inhibition.

Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). Seems to function as a tumor suppressor by regulating Notch trafficking, hence preventing non-autonomous overproliferation. May be invo [...]

Charged multivesicular body protein 2b (CHMP2B) encodes an ESCRT-III component. It plays an important role in the generation of multivesicular bodies in the endosomal lysosomal pathway. It is also considered to play an important role in autophagosome maturation.