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CG7069 CG7069 PyK PyK Akt1 Akt1 CG11249 CG11249 CG2964 CG2964 CG12229 CG12229 CROT CROT FASN1 FASN1 CG7362 CG7362 G6P G6P PCB PCB Pex11 Pex11 Pepck1 Pepck1 Pepck2 Pepck2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CG7069Pyruvate kinase activity; potassium ion binding; magnesium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. (744 aa)
PyKPyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family. (533 aa)
Akt1RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...] (611 aa)
CG11249Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. (642 aa)
CG2964Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. (554 aa)
CG12229AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. (571 aa)
CROTCarnitine O-octanoyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation. (618 aa)
FASN1Fatty acid synthase 1 (FASN1) encodes a fatty acid synthase involved in glycogen metabolism and triglyceride biosynthesis. (2540 aa)
CG7362Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. (793 aa)
G6PGlucose-6-phosphatase activity. It is involved in the biological process described with: gluconeogenesis; glucose 6-phosphate metabolic process. (350 aa)
PCBPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1197 aa)
Pex11Peroxin 11; It is involved in the biological process described with: regulation of peroxisome size; peroxisome fission; peroxisome organization. (241 aa)
Pepck1Phosphoenolpyruvate carboxykinase 1 (Pepck1) encodes an enzyme that converts oxaloacetate into phosphoenolpyruvate. It catalyzes the first committed step in gluconeogenesis and thus plays an essential role in glucose metabolism. (647 aa)
Pepck2Phosphoenolpyruvate carboxykinase (GTP) activity; manganese ion binding; GTP binding. (638 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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