Autophagy-related 8a (Atg8a) encodes a ubiquitin-like protein that is conjugated to phosphatidylethanolamine, and this lipid modification anchors it into the membrane of forming and completed autophagosomes. Atg8a product has roles in autophagosome formation, maintaining neuromuscular function and normal lifespan.

Autophagy-related 8b, isoform A; Microtubule binding; protein tag; ubiquitin protein ligase binding; GABA receptor binding. It is involved in the biological process described with: macroautophagy; autophagosome maturation; cellular response to nitrogen starvation; autophagy of mitochondrion; autophagosome assembly.

Autophagy-related 8a (Atg8a) encodes a ubiquitin-like protein that is conjugated to phosphatidylethanolamine, and this lipid modification anchors it into the membrane of forming and completed autophagosomes. Atg8a product has roles in autophagosome formation, maintaining neuromuscular function and normal lifespan.

Transmembrane GTPase Marf; Mitochondrial assembly regulatory factor (Marf) encodes a dynamin-family GTPase that mediates outer mitochondrial membrane tethering and fusion. Marf loss causes mitochondrial fragmentation and endoplasmic reticular stress that evoke skeletal muscle, retinal and heart tube dysfunction; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.

Autophagy-related 8a (Atg8a) encodes a ubiquitin-like protein that is conjugated to phosphatidylethanolamine, and this lipid modification anchors it into the membrane of forming and completed autophagosomes. Atg8a product has roles in autophagosome formation, maintaining neuromuscular function and normal lifespan.

Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...]

Autophagy-related 8b, isoform A; Microtubule binding; protein tag; ubiquitin protein ligase binding; GABA receptor binding. It is involved in the biological process described with: macroautophagy; autophagosome maturation; cellular response to nitrogen starvation; autophagy of mitochondrion; autophagosome assembly.

Autophagy-related 8a (Atg8a) encodes a ubiquitin-like protein that is conjugated to phosphatidylethanolamine, and this lipid modification anchors it into the membrane of forming and completed autophagosomes. Atg8a product has roles in autophagosome formation, maintaining neuromuscular function and normal lifespan.

Autophagy-related 8b, isoform A; Microtubule binding; protein tag; ubiquitin protein ligase binding; GABA receptor binding. It is involved in the biological process described with: macroautophagy; autophagosome maturation; cellular response to nitrogen starvation; autophagy of mitochondrion; autophagosome assembly.

Transmembrane GTPase Marf; Mitochondrial assembly regulatory factor (Marf) encodes a dynamin-family GTPase that mediates outer mitochondrial membrane tethering and fusion. Marf loss causes mitochondrial fragmentation and endoplasmic reticular stress that evoke skeletal muscle, retinal and heart tube dysfunction; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.

Autophagy-related 8b, isoform A; Microtubule binding; protein tag; ubiquitin protein ligase binding; GABA receptor binding. It is involved in the biological process described with: macroautophagy; autophagosome maturation; cellular response to nitrogen starvation; autophagy of mitochondrion; autophagosome assembly.

Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...]

Autophagy-related 8b, isoform A; Microtubule binding; protein tag; ubiquitin protein ligase binding; GABA receptor binding. It is involved in the biological process described with: macroautophagy; autophagosome maturation; cellular response to nitrogen starvation; autophagy of mitochondrion; autophagosome assembly.

Protein cueball; Has a role in spermatogenesis and oogenesis. Might have a role in triglyceride homeostasis. Probably by regulating lipid storage and catabolism, plays a role in neuronal function.

Uncharacterized protein; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; nuclear envelope reassembly; autophagosome assembly; membrane fusion; Golgi organization.

LD24832p; Ubiquitin-ubiquitin ligase activity. It is involved in the biological process described with: protein polyubiquitination; ubiquitin-dependent ERAD pathway; protein ubiquitination.

Uncharacterized protein; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; nuclear envelope reassembly; autophagosome assembly; membrane fusion; Golgi organization.

Nuclear protein localization protein 4 homolog; May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. Belongs to the NPL4 family.

Uncharacterized protein; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; nuclear envelope reassembly; autophagosome assembly; membrane fusion; Golgi organization.

Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling.

Uncharacterized protein; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; nuclear envelope reassembly; autophagosome assembly; membrane fusion; Golgi organization.

Syntaxin-5; Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis.

Uncharacterized protein; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; nuclear envelope reassembly; autophagosome assembly; membrane fusion; Golgi organization.

Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...]

Uncharacterized protein; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; nuclear envelope reassembly; autophagosome assembly; membrane fusion; Golgi organization.

Caspar, isoform A; Caspar (casp) encodes a protein that inhibits the immune deficiency pathway, but not the Toll pathway, by blocking cleavage and nuclear translocation of the product of Rel.

LD24832p; Ubiquitin-ubiquitin ligase activity. It is involved in the biological process described with: protein polyubiquitination; ubiquitin-dependent ERAD pathway; protein ubiquitination.

Uncharacterized protein; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; nuclear envelope reassembly; autophagosome assembly; membrane fusion; Golgi organization.

LD24832p; Ubiquitin-ubiquitin ligase activity. It is involved in the biological process described with: protein polyubiquitination; ubiquitin-dependent ERAD pathway; protein ubiquitination.

Nuclear protein localization protein 4 homolog; May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. Belongs to the NPL4 family.

LD24832p; Ubiquitin-ubiquitin ligase activity. It is involved in the biological process described with: protein polyubiquitination; ubiquitin-dependent ERAD pathway; protein ubiquitination.

Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling.

LD24832p; Ubiquitin-ubiquitin ligase activity. It is involved in the biological process described with: protein polyubiquitination; ubiquitin-dependent ERAD pathway; protein ubiquitination.

Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...]

LD24832p; Ubiquitin-ubiquitin ligase activity. It is involved in the biological process described with: protein polyubiquitination; ubiquitin-dependent ERAD pathway; protein ubiquitination.

Caspar, isoform A; Caspar (casp) encodes a protein that inhibits the immune deficiency pathway, but not the Toll pathway, by blocking cleavage and nuclear translocation of the product of Rel.

Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes (Probable); Belongs to the CAND family.

Cullin homolog 1; Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larv [...]

Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes (Probable); Belongs to the CAND family.

S-phase kinase-associated protein 2 (Skp2) encodes the substrate recognizing component of the SCF-Skp2 ubiquitin ligase. It functions with the product of Cks85A to target the product of dap for destruction. It is required for larval growth and to maintain diploidy in imaginal tissues.