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NPFR NPFR TrissinR TrissinR CCHa1 CCHa1 Trissin Trissin CG33639 CG33639 CCAP-R CCAP-R SIFa SIFa CrzR CrzR Dh31-R Dh31-R NPF NPF eEF1alpha1 eEF1alpha1 sNPF-R sNPF-R mGluR mGluR ETHR ETHR AstCC AstCC CCHa2-R CCHa2-R Orcokinin Orcokinin ETH ETH Eps-15 Eps-15 mth mth Akh Akh Itpr Itpr Proc Proc Crz Crz Burs Burs CCAP CCAP AstA AstA eEF1alpha2 eEF1alpha2 CCHa1-R CCHa1-R
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NPFRNeuropeptide F receptor; Receptor for NPF. Integral part of the sensory system that mediates food signaling, providing the neural basis for the regulation of food response; coordinates larval foraging and social behavior changes during development. Required in dopaminergic (DA) neurons that innervate the mushroom body for satiety to suppress appetitive memory performance; a key factor in the internal state of hunger in the brain. NPF neurons coordinately modulate diverse sensory and motor neurons important for feeding, flight, and locomotion. NPF/NPFR pathway exerts its suppressive eff [...] (489 aa)
TrissinRTrissin receptor; G-protein coupled receptor which is activated by the Trissin peptide in vitro, leading to increased intracellular calcium ion levels. (669 aa)
CCHa1Neuropeptide CCHamide-1; Ligand for the CCHamide-1 receptor CCHa1-R. (182 aa)
TrissinTrissin; Activates the G-protein coupled receptor TrissinR in vitro, leading to increased intracellular calcium ion levels. (108 aa)
CG33639IP11344p; G protein-coupled receptor activity; neuropeptide receptor activity. It is involved in the biological process described with: G protein-coupled receptor signaling pathway. (455 aa)
CCAP-RCardioacceleratory peptide receptor; Binds to the cardioactive peptide (CCAP), which is a neuropeptide; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (494 aa)
SIFaNeuropeptide SIFamide; Ligand for the neuropeptide SIFamide receptor. Modulates sexual behavior by negatively regulating female receptivity to male courtship and by playing a role in male sex discrimination. Also involved in promoting sleep. Belongs to the FARP (FMRFamide related peptide) family. (72 aa)
CrzRCorazonin receptor (CrzR) encodes a member of the Class A family of G-protein-coupled receptor that transduces the siganl of the neuropeptide encoded by Crz. It is involved in ethanol-induced behavior and ethanol metabolism. (644 aa)
Dh31-RDiuretic hormone 31 Receptor (Dh31-R) encodes a protein that exhibits diuretic hormone receptor activity. It is involved in G protein-coupled receptor signaling pathwayS; Belongs to the G-protein coupled receptor 2 family. (604 aa)
NPFNeuropeptide F; Integral part of the sensory system that mediates food signaling, providing the neural basis for the regulation of food response; coordinates larval foraging and social behavior changes during development. Required in dopaminergic (DA) neurons that innervate the mushroom body for satiety to suppress appetitive memory performance; a key factor in the internal state of hunger in the brain. NPF neurons coordinately modulate diverse sensory and motor neurons important for feeding, flight, and locomotion. NPF/NPFR pathway exerts its suppressive effect on larval aversion to d [...] (102 aa)
eEF1alpha1Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (463 aa)
sNPF-RShort neuropeptide F receptor (sNPF-R) encodes the G-protein-coupled receptor for the neuropeptide ligand encoded by sNPF, which utilizes the intracelluar ERK pathway or PKA-CREB pathway. It contributes to the regulation of growth, food intake, food-search behavior, appetitive memory, and sleep. (600 aa)
mGluRMetabotropic glutamate receptor; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. (976 aa)
ETHRETHR (ETHR) encodes two distinct G protein-coupled receptors through alternative splicing. During development, the receptors are essential in initiating the molt-related behaviors of ecdysis, and in adults they function to promote juvenile hormone signaling and reproduction. (471 aa)
AstCCAllatostatin double C, isoform C; Hormone activity. (261 aa)
CCHa2-RNeuropeptide CCHamide-2 receptor; Receptor for the neuropeptide CCHamide-2. Belongs to the G-protein coupled receptor 1 family. (501 aa)
OrcokininOrcokinin, isoform A. (133 aa)
ETHEcdysis triggering hormone (ETH) encodes two peptides (DrmETH1 and DrmETH2) involved in ecdysis. ETH depletion leads to respiratory and behavioral deficits, unsuccessful ecdysis and lethality. (203 aa)
Eps-15Epidermal growth factor receptor pathway substrate clone 15 (Eps-15) encodes a multi-domain adaptor protein involved in endocytosis. It interacts with several other endocytic factors such as those encoded by shi, stnB, Dap160 and AP-2alpha. It is enriched at sites of endocytosis and is required for normal synaptic bouton development and vesicle endocytosis during high frequency stimulation. (1253 aa)
mthG-protein coupled receptor Mth; Involved in biological aging and stress response. Essential for adult survival. Required in the presynaptic motor neuron to up- regulate neurotransmitter exocytosis at larval glutamatergic neuromuscular junctions (NMJs). Regulates a step associated with docking and clustering of vesicles at release sites. SP/Acp70A and sun are agonists that activate mth in vitro. Belongs to the G-protein coupled receptor 2 family. Mth subfamily. (522 aa)
AkhAdipokinetic hormone (Akh) encodes a peptide hormone secreted by the corpora cardiaca. It signals to the G-protein coupled receptor encoded by AkhR to regulate circulating hemolymph carbohydrates and stored lipid and glycogen in the fat body; Belongs to the AKH/HRTH/RPCH family. (79 aa)
ItprInositol 1,4,5,-trisphosphate receptor (Itpr) encodes an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itpr depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight; Belongs to the InsP3 receptor family. (2837 aa)
ProcProctolin, isoform A; Proctolin (Proc) encodes a neuropeptide precursor protein that binds the product of Proc-R and is involved in heart rate regulation. (140 aa)
CrzCorazonin (Crz) encodes a neuropeptide expressed in specific groups of neurons. It functions as a neurohormone and neuromodulator, which involves a G-protein-coupled receptor. Its roles include ethanol and trehalose metabolism, and male reproductive activity. (154 aa)
BursBursicon (Burs) encodes a cystine knot protein that dimerizes with the product of Pburs to form the bursicon neurohormone. Bursicon neurohormone is released after adult emergence and acts on the receptor encoded by rk for tanning and hardening of the cuticle and expansion of the wings. (173 aa)
CCAPCrustacean cardioactive peptide (CCAP) encodes a conserved 9 amino acid neuropeptide. It is produced by 1-2 neurons in each segment of the ventral nervous system and is released during the shedding of the old exoskeleton (ecdysis). It also has cardioactive functions. (155 aa)
AstAAllatostatin-A; May act as a neurotransmitter or neuromodulator. (151 aa)
eEF1alpha2Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (462 aa)
CCHa1-RNeuropeptide CCHamide-1 receptor; Receptor for the neuropeptide CCHamide-1. Plays a role in the modulation of starvation-induced olfactory behavior where starved flies show increased responsiveness to food odorants, repellants and pheromones. (499 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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