STRINGSTRING
Arf79F Arf79F IFT20 IFT20 Oseg5 Oseg5 betaTub56D betaTub56D IFT57 IFT57 Rab5 Rab5 IFT54 IFT54
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Arf79FADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. (182 aa)
IFT20Intraflagellar transport 20; It is involved in the biological process described with: centrosome localization; intraciliary transport; cilium assembly; protein localization to cilium. (131 aa)
Oseg5Outer segment 5; It is involved in the biological process described with: non-motile cilium assembly; cilium assembly. (775 aa)
betaTub56DTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (456 aa)
IFT57Intraflagellar transport protein 57 homolog; Required for the formation of cilia; Belongs to the IFT57 family. (405 aa)
Rab5Rab5, isoform A; Rab5 (Rab5) encodes a monomeric GTPase that controls entry of endocytosed cargo into the early endosome and is required for vesicle re-uptake at the synapse. Altering the activity of the product of Rab5 affects many receptor-mediated signaling pathways as well as epithelial polarity. (219 aa)
IFT54Intraflagellar transport 54; Microtubule binding. It is involved in the biological process described with: regulation of microtubule cytoskeleton organization; intraciliary transport; cilium assembly. (588 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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