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Mst98Cb Mst98Cb CTPsyn CTPsyn grsm grsm CG9314 CG9314 S-Lap3 S-Lap3 ScsbetaA ScsbetaA loopin-1 loopin-1 S-Lap7 S-Lap7 S-Lap5 S-Lap5 S-Lap8 S-Lap8 Fum2 Fum2 S-Lap4 S-Lap4 S-Lap1 S-Lap1 BBS1 BBS1 Decay Decay bb8 bb8 betaTub56D betaTub56D Rpt3 Rpt3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Mst98CbMale-specific RNA 98Cb; It is involved in the biological process described with: spermatid development. (265 aa)
CTPsynCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides (By similarity). Isoform 1 is required for cytoophidium assembly in female germline cells. (627 aa)
grsmGranny smith (grsm) encodes a member of the M17 family of leucine aminopeptidases, a family of proteases broadly involved in a number of cellular processes. High throughput transcriptomic and proteomic analyses have implicated the product of grsm in the regulation of immune-, nervous- and immune-related processes. (655 aa)
CG9314CG9314 protein; Catalase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; hydrogen peroxide catabolic process; response to hydrogen peroxide; oxidation-reduction process. (506 aa)
S-Lap3Sperm-Leucylaminopeptidase 3, isoform B; Manganese ion binding; metalloexopeptidase activity; aminopeptidase activity. It is involved in the biological process described with: proteolysis. (535 aa)
ScsbetaASuccinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (503 aa)
loopin-1Loopin-1, isoform A; Loopin-1 (loopin-1) encodes a testis-specific protein with homology to several leucine aminopeptidases. Sequence analysis suggest that it doesn't have enzymatic activity. It accumulates inside the axoneme-associated mitochondrial derivative in mature sperms. (526 aa)
S-Lap7Sperm-Leucylaminopeptidase 7, isoform A; Manganese ion binding; metalloexopeptidase activity; aminopeptidase activity. It is involved in the biological process described with: proteolysis; multicellular organism reproduction. (527 aa)
S-Lap5Sperm-Leucylaminopeptidase 5; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis; mesoderm development. (549 aa)
S-Lap8Sperm-Leucylaminopeptidase 8; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis. (534 aa)
Fum2Fumarase 2; Fumarate hydratase activity. It is involved in the biological process described with: tricarboxylic acid cycle; malate metabolic process; fumarate metabolic process. (503 aa)
S-Lap4Sperm-Leucylaminopeptidase 4; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis. (524 aa)
S-Lap1Sperm-Leucylaminopeptidase 1; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: mushroom body development; proteolysis. (555 aa)
BBS1Bardet-Biedl syndrome 1; Patched binding; smoothened binding. It is involved in the biological process described with: protein localization to cilium; non-motile cilium assembly; cilium assembly. (605 aa)
DecayDeath executioner caspase related to Apopain/Yama (Decay) encodes one of the seven members of the caspase family of cysteine proteases. It has substrate specificity similar to the effector caspases encoded by Drice and Dcp-1; Belongs to the peptidase C14A family. (308 aa)
bb8Big bubble 8 (bb8) encodes a glutamate dehydrogenase involved in the development of the spermatid mitochondria; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (535 aa)
betaTub56DTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (456 aa)
Rpt3Regulatory particle triple-A ATPase 3, isoform A; Proteasome-activating ATPase activity; ATPase activity; ATP binding. It is involved in the biological process described with: positive regulation of RNA polymerase II transcription preinitiation complex assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; protein catabolic process; Belongs to the AAA ATPase family. (413 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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