node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Akt1 | Dcr-2 | FBpp0082682 | FBpp0086061 | RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...] | Dicer-2, isoform A; Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. | 0.612 |
Akt1 | Ret | FBpp0082682 | FBpp0081021 | RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...] | Ret oncogene (Ret) encodes a cell surface receptor mediating dendrite development of class IV dendritic arborization sensory neurons. It interacts with integrins and mediates rac1 signaling to promote dendrite adhesion to the extracellular matrix; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.415 |
Akt1 | drosha | FBpp0082682 | FBpp0087926 | RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...] | Ribonuclease; Drosha (drosha) encodes a protein that contributes to miRNA processing. It is involved in salivary gland histolysis and oocyte development. | 0.553 |
Akt1 | elav | FBpp0082682 | FBpp0298002 | RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...] | Protein elav; Required for the proper development and maintenance of neurons presumably by affecting RNA metabolism. Belongs to the RRM elav family. | 0.401 |
Akt1 | lin-28 | FBpp0082682 | FBpp0076798 | RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...] | Protein lin-28 homolog; mRNA binding; zinc ion binding; mRNA 3'-UTR binding; Belongs to the lin-28 family. | 0.489 |
Akt1 | tau | FBpp0082682 | FBpp0311078 | RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...] | Microtubule-associated protein; Microtubule binding. It is involved in the biological process described with: neuron projection development; rhabdomere morphogenesis; negative regulation of neuron death; microtubule cytoskeleton organization. | 0.593 |
CG11249 | CG12229 | FBpp0078083 | FBpp0074988 | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. | 0.919 |
CG11249 | CG2964 | FBpp0078083 | FBpp0077406 | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | 0.913 |
CG11249 | CG7069 | FBpp0078083 | FBpp0083612 | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | Pyruvate kinase activity; potassium ion binding; magnesium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | 0.905 |
CG11249 | CG7362 | FBpp0078083 | FBpp0304089 | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | 0.908 |
CG11249 | PyK | FBpp0078083 | FBpp0083611 | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family. | 0.900 |
CG12229 | CG11249 | FBpp0074988 | FBpp0078083 | AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | 0.919 |
CG12229 | CG2964 | FBpp0074988 | FBpp0077406 | AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. | Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | 0.928 |
CG12229 | CG7069 | FBpp0074988 | FBpp0083612 | AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. | Pyruvate kinase activity; potassium ion binding; magnesium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | 0.909 |
CG12229 | CG7362 | FBpp0074988 | FBpp0304089 | AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | 0.916 |
CG12229 | PyK | FBpp0074988 | FBpp0083611 | AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. | Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family. | 0.911 |
CG2964 | CG11249 | FBpp0077406 | FBpp0078083 | Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | 0.913 |
CG2964 | CG12229 | FBpp0077406 | FBpp0074988 | Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process. | 0.928 |
CG2964 | CG7069 | FBpp0077406 | FBpp0083612 | Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | Pyruvate kinase activity; potassium ion binding; magnesium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | 0.913 |
CG2964 | CG7362 | FBpp0077406 | FBpp0304089 | Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process. | Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process. | 0.920 |