node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acph-1 | CG6656 | FBpp0084975 | FBpp0083537 | Acid phosphatase 1, isoform B; Acid phosphatase activity; protein homodimerization activity. It is involved in the biological process described with: dephosphorylation; Belongs to the histidine acid phosphatase family. | GH19849p; Acid phosphatase activity. It is involved in the biological process described with: dephosphorylation; Belongs to the histidine acid phosphatase family. | 0.909 |
CG6656 | Acph-1 | FBpp0083537 | FBpp0084975 | GH19849p; Acid phosphatase activity. It is involved in the biological process described with: dephosphorylation; Belongs to the histidine acid phosphatase family. | Acid phosphatase 1, isoform B; Acid phosphatase activity; protein homodimerization activity. It is involved in the biological process described with: dephosphorylation; Belongs to the histidine acid phosphatase family. | 0.909 |
Rab11 | Rab2 | FBpp0083413 | FBpp0085458 | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | Rab2, isoform A; Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. | 0.655 |
Rab11 | Rab27 | FBpp0083413 | FBpp0070280 | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | 0.532 |
Rab11 | Vps2 | FBpp0083413 | FBpp0084340 | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | Vacuolar protein sorting 2 (Vps2) encodes an ion channel involved in the transmembrane transport of potassium. | 0.420 |
Rab2 | Rab11 | FBpp0085458 | FBpp0083413 | Rab2, isoform A; Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | 0.655 |
Rab2 | Rab27 | FBpp0085458 | FBpp0070280 | Rab2, isoform A; Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | 0.530 |
Rab27 | Rab11 | FBpp0070280 | FBpp0083413 | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | 0.532 |
Rab27 | Rab2 | FBpp0070280 | FBpp0085458 | EG:80H7.4 protein; Rab27 (Rab27) encodes a Rab GTPase involved in exosomal secretion. | Rab2, isoform A; Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. | 0.530 |
Vps2 | Rab11 | FBpp0084340 | FBpp0083413 | Vacuolar protein sorting 2 (Vps2) encodes an ion channel involved in the transmembrane transport of potassium. | Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. | 0.420 |
Vps2 | Vps24 | FBpp0084340 | FBpp0312584 | Vacuolar protein sorting 2 (Vps2) encodes an ion channel involved in the transmembrane transport of potassium. | Vacuolar protein sorting 24 (Vps24) encodes an essential subunit of ESCRT-III, one of the endosomal sorting complexes required for transport (ESCRT). It is involved in membrane remodeling in diverse cellular processes, such as multi-vesicular body biogenesis, cytokinesis and virus budding. | 0.999 |
Vps2 | Vps25 | FBpp0084340 | FBpp0087774 | Vacuolar protein sorting 2 (Vps2) encodes an ion channel involved in the transmembrane transport of potassium. | Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). Seems to function as a tumor suppressor by regulating Notch trafficking, hence preventing non-autonomous overproliferation. May be invo [...] | 0.987 |
Vps2 | Vps4 | FBpp0084340 | FBpp0309628 | Vacuolar protein sorting 2 (Vps2) encodes an ion channel involved in the transmembrane transport of potassium. | Vacuolar protein sorting 4 (Vps4) encodes an AAA family ATPase. It catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes. It functions in endosomal sorting of cargo into the multivesicular body for lysosomal degradation, abscission during cell division, virus release and nuclear envelope membrane sealing after cell division. | 0.998 |
Vps2 | Vps60 | FBpp0084340 | FBpp0305334 | Vacuolar protein sorting 2 (Vps2) encodes an ion channel involved in the transmembrane transport of potassium. | Charged multivesicular body protein 5; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity). Specifically down-regulates Notch signaling activity in the germarium, probably by facilitating Notch en [...] | 0.998 |
Vps24 | Vps2 | FBpp0312584 | FBpp0084340 | Vacuolar protein sorting 24 (Vps24) encodes an essential subunit of ESCRT-III, one of the endosomal sorting complexes required for transport (ESCRT). It is involved in membrane remodeling in diverse cellular processes, such as multi-vesicular body biogenesis, cytokinesis and virus budding. | Vacuolar protein sorting 2 (Vps2) encodes an ion channel involved in the transmembrane transport of potassium. | 0.999 |
Vps24 | Vps25 | FBpp0312584 | FBpp0087774 | Vacuolar protein sorting 24 (Vps24) encodes an essential subunit of ESCRT-III, one of the endosomal sorting complexes required for transport (ESCRT). It is involved in membrane remodeling in diverse cellular processes, such as multi-vesicular body biogenesis, cytokinesis and virus budding. | Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). Seems to function as a tumor suppressor by regulating Notch trafficking, hence preventing non-autonomous overproliferation. May be invo [...] | 0.983 |
Vps24 | Vps4 | FBpp0312584 | FBpp0309628 | Vacuolar protein sorting 24 (Vps24) encodes an essential subunit of ESCRT-III, one of the endosomal sorting complexes required for transport (ESCRT). It is involved in membrane remodeling in diverse cellular processes, such as multi-vesicular body biogenesis, cytokinesis and virus budding. | Vacuolar protein sorting 4 (Vps4) encodes an AAA family ATPase. It catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes. It functions in endosomal sorting of cargo into the multivesicular body for lysosomal degradation, abscission during cell division, virus release and nuclear envelope membrane sealing after cell division. | 0.986 |
Vps24 | Vps60 | FBpp0312584 | FBpp0305334 | Vacuolar protein sorting 24 (Vps24) encodes an essential subunit of ESCRT-III, one of the endosomal sorting complexes required for transport (ESCRT). It is involved in membrane remodeling in diverse cellular processes, such as multi-vesicular body biogenesis, cytokinesis and virus budding. | Charged multivesicular body protein 5; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and are delivered to lysosomes enabling degradation of membrane proteins (By similarity). Specifically down-regulates Notch signaling activity in the germarium, probably by facilitating Notch en [...] | 0.998 |
Vps25 | Vps2 | FBpp0087774 | FBpp0084340 | Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). Seems to function as a tumor suppressor by regulating Notch trafficking, hence preventing non-autonomous overproliferation. May be invo [...] | Vacuolar protein sorting 2 (Vps2) encodes an ion channel involved in the transmembrane transport of potassium. | 0.987 |
Vps25 | Vps24 | FBpp0087774 | FBpp0312584 | Vacuolar protein-sorting-associated protein 25; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). Seems to function as a tumor suppressor by regulating Notch trafficking, hence preventing non-autonomous overproliferation. May be invo [...] | Vacuolar protein sorting 24 (Vps24) encodes an essential subunit of ESCRT-III, one of the endosomal sorting complexes required for transport (ESCRT). It is involved in membrane remodeling in diverse cellular processes, such as multi-vesicular body biogenesis, cytokinesis and virus budding. | 0.983 |