Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Cecropin-C; Cecropin C (CecC) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is strongly expressed at the pupal stage.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Diptericin A (DptA) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway; Belongs to the attacin/sarcotoxin-2 family.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Diptericin B (DptB) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Inhibitor of nuclear factor kappa-B kinase subunit beta; Required for the activation of the NF-kappa-B factor Relish (Rel) by acting as an essential signaling component in transmitting the lipopolysaccharide (LPS) signal leading to cact degradation, which is required for direct activation of Rel. Phosphorylates inhibitors of NF- kappa-B (cact) thus leading to the dissociation of the inhibitor/NF- kappa-B complex and ultimately the degradation of the NF-kappa-B inhibitor. Essential for antibacterial immune response.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Myd88 (Myd88) encodes an adaptor protein involved in in the Toll pathway functioning downstream of the product of Tl and upstream of the product of tub. Toll pathway is a signaling cascade that plays a key role in various developmental and immune processes, notably embryonic dorsoventral patterning and regulation of antimicrobial peptides.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Peptidoglycan-recognition protein LC; Major activator of the imd/Relish pathway and is likely to encode a pattern recognition molecule for the humoral immune response. Required for Relish processing and nuclear translocation following proteolytic cleavage. Involved in the response to lipopolysaccharide (LPS) and peptidoglycan of Gram-negative bacteria. The different isoforms probably display different recognition capabilities to various microbial patterns. [Isoform x]: Mediates the response to LPS, peptidoglycan and Gram-negative bacteria; Belongs to the N-acetylmuramoyl-L-alanine amid [...]

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Nuclear factor NF-kappa-B p110 subunit; Plays a key role in the humoral immune response. Rel-p68 subunit translocates to the nucleus where it binds to the promoter of the Cecropin A1 gene and probably other antimicrobial peptide genes. I-kappa-B kinase complex (IKKbeta and key) and PGRP-LC are essential signaling components in transmitting the lipopolysaccharide (LPS) signal leading to cact degradation for NF-kappa-B (rel) activation. Part of a Toll-related receptor pathway that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo sig [...]

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

TAK1-associated binding protein 2 (Tab2) encodes a protein with an ubiquitin binding domain. It interacts with the product of Tak1, a MAP kinase kinase kinase involved the activation of the immune deficiency, JNK and Grindelwald-Eiger pathways.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Protein immune deficiency; Essential for the imd/NF-kappa-B (Imd) humoral and epithelial immune response to Gram-negative bacteria. Functions as an adapter protein that transduces immunity signals from the activation of pathogen recognition receptors (PRRs) by bacterial infection to the Imd signaling pathway. Binding of diaminopimelic acid-type (DAP-type) bacterial peptidoglycans (PGN) causes multimerization or clustering of PGRP receptors which activate the Imd cascade probably by recruiting imd, Fadd and Dredd to the receptor complex. Once in proximity, Dredd cleaves imd in a Fadd-de [...]

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Cecropin-A1; Cecropin A1 (CecA1) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia, and it is regulated at the transcriptional level, mostly by the immune deficiency pathway; Belongs to the cecropin family.

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Cecropin-C; Cecropin C (CecC) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is strongly expressed at the pupal stage.

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily.

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Diptericin A (DptA) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway; Belongs to the attacin/sarcotoxin-2 family.

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Diptericin B (DptB) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway.

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Myd88 (Myd88) encodes an adaptor protein involved in in the Toll pathway functioning downstream of the product of Tl and upstream of the product of tub. Toll pathway is a signaling cascade that plays a key role in various developmental and immune processes, notably embryonic dorsoventral patterning and regulation of antimicrobial peptides.

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Peptidoglycan-recognition protein LC; Major activator of the imd/Relish pathway and is likely to encode a pattern recognition molecule for the humoral immune response. Required for Relish processing and nuclear translocation following proteolytic cleavage. Involved in the response to lipopolysaccharide (LPS) and peptidoglycan of Gram-negative bacteria. The different isoforms probably display different recognition capabilities to various microbial patterns. [Isoform x]: Mediates the response to LPS, peptidoglycan and Gram-negative bacteria; Belongs to the N-acetylmuramoyl-L-alanine amid [...]

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

Nuclear factor NF-kappa-B p110 subunit; Plays a key role in the humoral immune response. Rel-p68 subunit translocates to the nucleus where it binds to the promoter of the Cecropin A1 gene and probably other antimicrobial peptide genes. I-kappa-B kinase complex (IKKbeta and key) and PGRP-LC are essential signaling components in transmitting the lipopolysaccharide (LPS) signal leading to cact degradation for NF-kappa-B (rel) activation. Part of a Toll-related receptor pathway that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo sig [...]

Cecropin-B; Cecropin B (CecB) encodes an helicoidal antibacterial peptide with activity against Gram-negative bacteria. It is mostly expressed at the pupal stage; Belongs to the cecropin family.

TAK1-associated binding protein 2 (Tab2) encodes a protein with an ubiquitin binding domain. It interacts with the product of Tak1, a MAP kinase kinase kinase involved the activation of the immune deficiency, JNK and Grindelwald-Eiger pathways.