STRINGSTRING
CG43089 CG43089 SkpB SkpB SkpA SkpA Fhos Fhos SkpF SkpF CG15800 CG15800 SkpD SkpD SkpC SkpC SkpE SkpE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CG43089GEO10396p1; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family. (144 aa)
SkpBCullin family protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. (161 aa)
SkpASKP1-related A (SkpA) encodes a subunit of Skp, Cullin, F-box (SCF)-containing ubiquitin ligase complexes. It regulates centrosome duplication, chromatin condensation, cell cycle progression, cell polarity, dendrite pruning and endoreduplication. (162 aa)
FhosFormin homology 2 domain containing (Fhos) encodes a protein that regulates actin-dependent remodeling of muscle cytoskeleton via induction of actin stress fibers, directs macrophage migration during cellular immune response, and is involved in autophagic programmed cell death. (2528 aa)
SkpFCullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family. (171 aa)
CG15800Skp1_POZ domain-containing protein; Cullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family. (157 aa)
SkpDCullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family. (158 aa)
SkpCCullin family protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family. (158 aa)
SkpECullin family protein binding. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; Belongs to the SKP1 family. (167 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.