node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AttB | Dcr-2 | FBpp0290164 | FBpp0086061 | Attacin-B (AttB) encodes an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria; Belongs to the attacin/sarcotoxin-2 family. | Dicer-2, isoform A; Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. | 0.493 |
Dcr-2 | AttB | FBpp0086061 | FBpp0290164 | Dicer-2, isoform A; Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. | Attacin-B (AttB) encodes an immune inducible peptide that shows homology to antibacterial peptides having activity against Gram-negative bacteria; Belongs to the attacin/sarcotoxin-2 family. | 0.493 |
Dcr-2 | Fib | FBpp0086061 | FBpp0071892 | Dicer-2, isoform A; Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. | rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gl [...] | 0.525 |
Dcr-2 | Tsen54 | FBpp0086061 | FBpp0075748 | Dicer-2, isoform A; Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. | tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. | 0.596 |
Fib | Dcr-2 | FBpp0071892 | FBpp0086061 | rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gl [...] | Dicer-2, isoform A; Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. | 0.525 |
Pcf11 | Tsen15 | FBpp0291500 | FBpp0087675 | Protein 1 of cleavage and polyadenylation factor 1 (Pcf11) encodes an RNA binding protein involved in RNA splicing regulation. | Uncharacterized protein, isoform A; tRNA-intron endonuclease activity. It is involved in the biological process described with: tRNA splicing, via endonucleolytic cleavage and ligation. | 0.492 |
Pcf11 | Tsen54 | FBpp0291500 | FBpp0075748 | Protein 1 of cleavage and polyadenylation factor 1 (Pcf11) encodes an RNA binding protein involved in RNA splicing regulation. | tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. | 0.409 |
Tsen15 | Pcf11 | FBpp0087675 | FBpp0291500 | Uncharacterized protein, isoform A; tRNA-intron endonuclease activity. It is involved in the biological process described with: tRNA splicing, via endonucleolytic cleavage and ligation. | Protein 1 of cleavage and polyadenylation factor 1 (Pcf11) encodes an RNA binding protein involved in RNA splicing regulation. | 0.492 |
Tsen15 | Tsen34 | FBpp0087675 | FBpp0291628 | Uncharacterized protein, isoform A; tRNA-intron endonuclease activity. It is involved in the biological process described with: tRNA splicing, via endonucleolytic cleavage and ligation. | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] | 0.999 |
Tsen15 | Tsen54 | FBpp0087675 | FBpp0075748 | Uncharacterized protein, isoform A; tRNA-intron endonuclease activity. It is involved in the biological process described with: tRNA splicing, via endonucleolytic cleavage and ligation. | tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. | 0.998 |
Tsen34 | Tsen15 | FBpp0291628 | FBpp0087675 | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] | Uncharacterized protein, isoform A; tRNA-intron endonuclease activity. It is involved in the biological process described with: tRNA splicing, via endonucleolytic cleavage and ligation. | 0.999 |
Tsen34 | Tsen54 | FBpp0291628 | FBpp0075748 | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] | tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. | 0.999 |
Tsen54 | Dcr-2 | FBpp0075748 | FBpp0086061 | tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. | Dicer-2, isoform A; Dicer-2 (Dcr-2) encodes a member of the RNase III family of double-stranded RNA-specific endonucleases. It acts in the RNAi pathway by cutting long dsRNA into siRNAs. It helps defend flies against viral infection, particularly RNA viruses. It also processes long, partially double-stranded endogenous transcripts (hairpin RNAs) into endo-siRNAs. | 0.596 |
Tsen54 | Pcf11 | FBpp0075748 | FBpp0291500 | tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. | Protein 1 of cleavage and polyadenylation factor 1 (Pcf11) encodes an RNA binding protein involved in RNA splicing regulation. | 0.409 |
Tsen54 | Tsen15 | FBpp0075748 | FBpp0087675 | tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. | Uncharacterized protein, isoform A; tRNA-intron endonuclease activity. It is involved in the biological process described with: tRNA splicing, via endonucleolytic cleavage and ligation. | 0.998 |
Tsen54 | Tsen34 | FBpp0075748 | FBpp0291628 | tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] | 0.999 |