(8 nodes) (2021) Bdellovibrio bacteriovorus phosphoglucose isomerase structures reveal novel rigidity in the active site of a selected subset of enzymes upon substrate binding. network (Drosophila melanogaster)

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Your Input:
	GstD8	Glutathione S transferase D8 (GstD8) encodes an enzyme with broad substrate specificity involved in glutathione metabolism. (212 aa)
	dind	Diamond, isoform A. (592 aa)
	GstE12	Glutathione S transferase E12 (GstE12) encodes an enzyme involved in glutathione metabolism; Belongs to the GST superfamily. (223 aa)
	GstD1	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification. (209 aa)
	Gapdh1	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle. (332 aa)
	Pgi	Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis. (558 aa)
	CG9010	Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process. (343 aa)
	Gapdh2	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG9010	Gapdh1	FBpp0086215	FBpp0087977	Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process.	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.	0.901
CG9010	Gapdh2	FBpp0086215	FBpp0073922	Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process.	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.901
CG9010	Pgi	FBpp0086215	FBpp0087760	Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process.	Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis.	0.978
Gapdh1	CG9010	FBpp0087977	FBpp0086215	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.	Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process.	0.901
Gapdh1	Gapdh2	FBpp0087977	FBpp0073922	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.999
Gapdh1	GstD1	FBpp0087977	FBpp0099824	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.	0.445
Gapdh1	Pgi	FBpp0087977	FBpp0087760	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.	Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis.	0.994
Gapdh2	CG9010	FBpp0073922	FBpp0086215	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process.	0.901
Gapdh2	Gapdh1	FBpp0073922	FBpp0087977	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.	0.999
Gapdh2	GstD1	FBpp0073922	FBpp0099824	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.	0.865
Gapdh2	Pgi	FBpp0073922	FBpp0087760	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis.	0.989
GstD1	Gapdh1	FBpp0099824	FBpp0087977	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.	Glyceraldehyde 3 phosphate dehydrogenase 1 (Gapdh1) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glycolysis, myoblast fusion and the development of somatic muscle.	0.445
GstD1	Gapdh2	FBpp0099824	FBpp0073922	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.	Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.865
GstD1	GstD8	FBpp0099824	FBpp0082047	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.	Glutathione S transferase D8 (GstD8) encodes an enzyme with broad substrate specificity involved in glutathione metabolism.	0.998
GstD1	GstE12	FBpp0099824	FBpp0293853	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.	Glutathione S transferase E12 (GstE12) encodes an enzyme involved in glutathione metabolism; Belongs to the GST superfamily.	0.774
GstD8	GstD1	FBpp0082047	FBpp0099824	Glutathione S transferase D8 (GstD8) encodes an enzyme with broad substrate specificity involved in glutathione metabolism.	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.	0.998
GstD8	GstE12	FBpp0082047	FBpp0293853	Glutathione S transferase D8 (GstD8) encodes an enzyme with broad substrate specificity involved in glutathione metabolism.	Glutathione S transferase E12 (GstE12) encodes an enzyme involved in glutathione metabolism; Belongs to the GST superfamily.	0.691
GstE12	GstD1	FBpp0293853	FBpp0099824	Glutathione S transferase E12 (GstE12) encodes an enzyme involved in glutathione metabolism; Belongs to the GST superfamily.	Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.	0.774
GstE12	GstD8	FBpp0293853	FBpp0082047	Glutathione S transferase E12 (GstE12) encodes an enzyme involved in glutathione metabolism; Belongs to the GST superfamily.	Glutathione S transferase D8 (GstD8) encodes an enzyme with broad substrate specificity involved in glutathione metabolism.	0.691
Pgi	CG9010	FBpp0087760	FBpp0086215	Phosphoglucose isomerase (Pgi) encodes an enzyme involved in glucose homeostasis.	Glyceraldehyde-3-phosphate dehydrogenase; Peptidyl-cysteine S-nitrosylase activity; NADP binding; NAD binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. It is involved in the biological process described with: oxidation-reduction process; glycolytic process; glucose metabolic process.	0.978