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Npc2e Npc2e CG10097 CG10097 CG10096 CG10096 CG34342 CG34342 CG4020 CG4020 Sgp Sgp CG12268 CG12268 CG14893 CG14893 FarO FarO CG4586 CG4586 Acox57D-p Acox57D-p Acox57D-d Acox57D-d CG30427 CG30427 Npc2a Npc2a Npc1a Npc1a CG17544 CG17544 Npc2c Npc2c Npc2d Npc2d Npc2b Npc2b CG17562 CG17562 CG17560 CG17560 CG4770 CG4770 Npc2f Npc2f Npc2h Npc2h Npc2g Npc2g CG1441 CG1441 CG5009 CG5009 Pld Pld CG9527 CG9527
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Npc2eNiemann-Pick type C-2e (Npc2e) encodes a protein involved in the immune signaling pathway via interaction with lipopolysaccharide, lipid A, peptidoglycan and lipoteichoic acid. (168 aa)
CG10097Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (501 aa)
CG10096Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (502 aa)
CG34342Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (572 aa)
CG4020Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (494 aa)
SgpFatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (523 aa)
CG12268Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (531 aa)
CG14893Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (510 aa)
FarOFatty acyl-CoA reductase in oenocytes (FarO) encodes a long-chain-fatty-acyl-CoA reductase involved in the regulation of cell growth and lipid storage. (504 aa)
CG4586Acyl-coenzyme A oxidase; Flavin adenine dinucleotide binding; FAD binding; fatty acid binding; acyl-CoA oxidase activity. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase. (677 aa)
Acox57D-pAcyl-coenzyme A oxidase; Flavin adenine dinucleotide binding; acyl-CoA oxidase activity; FAD binding; fatty acid binding. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase. (677 aa)
Acox57D-dAcyl-coenzyme A oxidase; FAD binding; fatty acid binding; acyl-CoA oxidase activity; flavin adenine dinucleotide binding. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase. (677 aa)
CG30427CG30427 encodes a fatty-acyl-CoA reductase involved in production of NADPH, sensory perception of pain, phagocytosis and determination of lifespan. (506 aa)
Npc2aNPC intracellular cholesterol transporter 2 homolog a; Functions redundantly with Npc2b in regulating sterol homeostasis and ecdysteroid biosynthesis, probably by controlling the availability of sterol substrate. (148 aa)
Npc1aNiemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization. (1287 aa)
CG17544acyl-CoA oxidase activity; fatty acid binding; FAD binding; flavin adenine dinucleotide binding; pristanoyl-CoA oxidase activity. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase. (693 aa)
Npc2cNiemann-Pick type C-2c; Sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. (165 aa)
Npc2dNiemann-Pick type C-2d; Sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. (173 aa)
Npc2bNiemann-Pick type C-2b, isoform A; Sterol binding. It is involved in the biological process described with: multicellular organism reproduction; ecdysteroid biosynthetic process; intracellular cholesterol transport; sterol transport. (159 aa)
CG17562Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (499 aa)
CG17560Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (499 aa)
CG4770Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (490 aa)
Npc2fNiemann-Pick type C-2f; Sterol binding. It is involved in the biological process described with: intracellular cholesterol transport; sterol transport. (170 aa)
Npc2hNiemann-Pick type C-2h (Npc2h) encodes a protein involved in immune signaling via interaction with lipopolysaccharides, lipid A, peptidoglycan and lipoteichoic acid. (157 aa)
Npc2gNiemann-Pick type C-2g, isoform A; Sterol binding. It is involved in the biological process described with: intracellular cholesterol transport; sterol transport; mesoderm development. (159 aa)
CG1441Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (517 aa)
CG5009Probable peroxisomal acyl-coenzyme A oxidase 1; Flavin adenine dinucleotide binding; fatty acid binding; FAD binding; acyl-CoA oxidase activity; Belongs to the acyl-CoA oxidase family. (669 aa)
PldPhospholipase; Phosphatidylinositol binding; phospholipase D activity. (1364 aa)
CG9527Acyl-coenzyme A oxidase; Fatty acid binding; FAD binding; acyl-CoA oxidase activity; pristanoyl-CoA oxidase activity; flavin adenine dinucleotide binding. It is involved in the biological process described with: lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid beta-oxidation. (724 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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