STRINGSTRING
RtcB RtcB Tsen54 Tsen54 CG33057 CG33057 Ddx1 Ddx1 Sas-4 Sas-4 Decay Decay Archease Archease cbc cbc pcm pcm
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
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RtcBRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family. (506 aa)
Tsen54tRNA_int_end_N2 domain-containing protein; It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. (383 aa)
CG33057GH08776p; tRNA 2'-phosphotransferase activity. It is involved in the biological process described with: tRNA processing; tRNA splicing, via endonucleolytic cleavage and ligation. (212 aa)
Ddx1ATP-dependent RNA helicase Ddx1; Dead-box-1 (Ddx1) encodes a member of the DEAD box family of RNA helicases that bind and unwind double-stranded RNA. Ddx1 product depletion is associated with small size and aberrant gametogenesis, possibly through alternative splicing of Sirup RNA transcript. (727 aa)
Sas-4Spindle assembly abnormal 4 (Sas-4) encodes a centriole protein that is essential for centriole assembly. It is recruited to centrioles through an interaction with the centriole protein encoded by ana2, and it helps recruit microtubules to the centriole. (901 aa)
DecayDeath executioner caspase related to Apopain/Yama (Decay) encodes one of the seven members of the caspase family of cysteine proteases. It has substrate specificity similar to the effector caspases encoded by Drice and Dcp-1; Belongs to the peptidase C14A family. (308 aa)
ArcheaseProtein archease-like; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB (CG9987). (156 aa)
cbcProtein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily. (423 aa)
pcm5'-3' exoribonuclease 1; Pacman (pcm) encodes an exoribonuclease that degrades decapped mRNA. It is involved in epithelial closure, male fertility, apoptosis and growth control. (1613 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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