(5 nodes) (2022) Mitochondrial RNA modifications shape metabolic plasticity in metastasis. network (Drosophila melanogaster)

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Your Input:
	term	Protein terminus; Nucleic acid binding. (428 aa)
	Gp93	Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. (787 aa)
	TFAM	Mitochondrial transcription factor A (TFAM) encodes a protein essential for mtDNA transcription and replication. It also binds to mtDNA nonspecifically, and plays a role in mtDNA maintenance by packaging mtDNA. (284 aa)
	srl	Spargel, isoform B; Transcription coregulator activity; mRNA binding; nuclear receptor transcription coactivator activity; transcription factor binding; nucleic acid binding. (1067 aa)
	Nsun2	tRNA (cytosine(34)-C(5))-methyltransferase; RNA methyltransferase that methylates tRNAs. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Required for short-term memory. (746 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gp93	srl	FBpp0084623	FBpp0078586	Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development.	Spargel, isoform B; Transcription coregulator activity; mRNA binding; nuclear receptor transcription coactivator activity; transcription factor binding; nucleic acid binding.	0.450
TFAM	srl	FBpp0083356	FBpp0078586	Mitochondrial transcription factor A (TFAM) encodes a protein essential for mtDNA transcription and replication. It also binds to mtDNA nonspecifically, and plays a role in mtDNA maintenance by packaging mtDNA.	Spargel, isoform B; Transcription coregulator activity; mRNA binding; nuclear receptor transcription coactivator activity; transcription factor binding; nucleic acid binding.	0.930
srl	Gp93	FBpp0078586	FBpp0084623	Spargel, isoform B; Transcription coregulator activity; mRNA binding; nuclear receptor transcription coactivator activity; transcription factor binding; nucleic acid binding.	Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development.	0.450
srl	TFAM	FBpp0078586	FBpp0083356	Spargel, isoform B; Transcription coregulator activity; mRNA binding; nuclear receptor transcription coactivator activity; transcription factor binding; nucleic acid binding.	Mitochondrial transcription factor A (TFAM) encodes a protein essential for mtDNA transcription and replication. It also binds to mtDNA nonspecifically, and plays a role in mtDNA maintenance by packaging mtDNA.	0.930