CMP/dCMP-type deaminase domain-containing protein; Cytidine deaminase activity; zinc ion binding. It is involved in the biological process described with: cytidine deamination.

Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.

CMP/dCMP-type deaminase domain-containing protein; Cytidine deaminase activity; zinc ion binding. It is involved in the biological process described with: cytidine deamination.

Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.

CMP/dCMP-type deaminase domain-containing protein; Cytidine deaminase activity; zinc ion binding. It is involved in the biological process described with: cytidine deamination.

Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.

Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

CMP/dCMP-type deaminase domain-containing protein; Cytidine deaminase activity; zinc ion binding. It is involved in the biological process described with: cytidine deamination.

Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.

Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family.

DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]

Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family.

Origin recognition complex subunit 1 (Orc1) encodes the largest subunit of the origin recognition complex (ORC), which is essential for the initiation of DNA replication in eukaryotic cells. The ATPase activity of the product of Orc1 is critical for the formation and function of the pre-replicative complex. The regulated degradation of the product of Orc1 by ubiquitin-mediated proteolysis after initiation of DNA replication helps to prevent re-replication.

Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family.

Origin recognition complex subunit 3 (Orc3) encodes a subunit of the origin recognition complex. It is involved in DNA replication initiation and border follicle cell migration regulation.

Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family.

Origin recognition complex subunit 4 (Orc4) encodes is a subunit of the hetero-hexameric origin recognition complex (ORC). The ORC binds to origins of DNA replication and scaffolds assembly of a pre-replicative complex, which is required for the initiation of DNA replication. At other loci, the ORC is required for heterochromatin formation.

Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family.

Regulatory particle triple-A ATPase 3, isoform A; Proteasome-activating ATPase activity; ATPase activity; ATP binding. It is involved in the biological process described with: positive regulation of RNA polymerase II transcription preinitiation complex assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; protein catabolic process; Belongs to the AAA ATPase family.

Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family.

Double parked (dup) encodes an essential protein for the initiation of DNA replication due to its recruitment of the MCM helicase to replication origins.

HIF prolyl hydroxylase (Hph) encodes the prolyl-4 hydroxylase that hydroxylases proline 850a of the product of sima, which is the alpha-subunit of the hypoxia inducible factor (HIF). The product of Hph regulates growth through both independent and dependent mechanisms of the product of sima.

Regulatory particle triple-A ATPase 3, isoform A; Proteasome-activating ATPase activity; ATPase activity; ATP binding. It is involved in the biological process described with: positive regulation of RNA polymerase II transcription preinitiation complex assembly; proteasome-mediated ubiquitin-dependent protein catabolic process; protein catabolic process; Belongs to the AAA ATPase family.

DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]

Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family.

DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]

Origin recognition complex subunit 1 (Orc1) encodes the largest subunit of the origin recognition complex (ORC), which is essential for the initiation of DNA replication in eukaryotic cells. The ATPase activity of the product of Orc1 is critical for the formation and function of the pre-replicative complex. The regulated degradation of the product of Orc1 by ubiquitin-mediated proteolysis after initiation of DNA replication helps to prevent re-replication.

DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]

Origin recognition complex subunit 3 (Orc3) encodes a subunit of the origin recognition complex. It is involved in DNA replication initiation and border follicle cell migration regulation.

DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]

Origin recognition complex subunit 4 (Orc4) encodes is a subunit of the hetero-hexameric origin recognition complex (ORC). The ORC binds to origins of DNA replication and scaffolds assembly of a pre-replicative complex, which is required for the initiation of DNA replication. At other loci, the ORC is required for heterochromatin formation.

DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]

Double parked (dup) encodes an essential protein for the initiation of DNA replication due to its recruitment of the MCM helicase to replication origins.

Origin recognition complex subunit 1 (Orc1) encodes the largest subunit of the origin recognition complex (ORC), which is essential for the initiation of DNA replication in eukaryotic cells. The ATPase activity of the product of Orc1 is critical for the formation and function of the pre-replicative complex. The regulated degradation of the product of Orc1 by ubiquitin-mediated proteolysis after initiation of DNA replication helps to prevent re-replication.

Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family.

Origin recognition complex subunit 1 (Orc1) encodes the largest subunit of the origin recognition complex (ORC), which is essential for the initiation of DNA replication in eukaryotic cells. The ATPase activity of the product of Orc1 is critical for the formation and function of the pre-replicative complex. The regulated degradation of the product of Orc1 by ubiquitin-mediated proteolysis after initiation of DNA replication helps to prevent re-replication.

DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]