RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...]

Calcium ion binding; unfolded protein binding. It is involved in the biological process described with: protein folding; endoplasmic reticulum unfolded protein response.

RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...]

Calnexin 14D; Calcium ion binding; unfolded protein binding. It is involved in the biological process described with: endoplasmic reticulum unfolded protein response; protein folding.

RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...]

Integrin beta-nu; Contributes to endodermal integrity and adhesion between the midgut epithelium and the surrounding visceral muscle. Essential for migration of the primordial midgut cells and for maintaining, but not establishing, cell polarity in the midgut epithelium. Can only partially compensate for the loss of beta-PS integrin during primordial midgut cell migration. The two beta subunits mediate midgut migration by distinct mechanisms: beta-PS requires rhea/Talin and beta-nu does not. Integrin alpha-PS3/beta-nu is required for effective phagocytosis of apoptotic cells during emb [...]

RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...]

[Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial; Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism; Belongs to the PDK/BCKDK protein kinase family.

RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...]

Forkhead box protein O; Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thord4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself m [...]

RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...]

Integrin beta-PS; Integrin alpha-PS1/beta-PS is a receptor for laminin. Integrin alpha-PS2/beta-PS is a receptor for Tig, wb and Ten-m. Contributes to endodermal integrity and adhesion between the midgut epithelium and the surrounding visceral muscle. Essential for migration of the primordial midgut cells and for maintaining, but not establishing, cell polarity in the midgut epithelium. The two beta subunits mediate midgut migration by distinct mechanisms: beta-PS requires rhea/talin and Itgbn does not. Required for rhea/talin correct cellular localization in the midgut. Required for m [...]

RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...]

Viking, isoform A; Viking (vkg) encodes a subunit of Collagen IV and a major component of basement membranes. It is secreted by haemocytes and fat body cells and is required for the normal morphogenesis of many tissues. It also contributes to TGF-beta signalling in the early embryo and the developing Malpighian tubules.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.

AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.

Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.

Pyruvate kinase activity; potassium ion binding; magnesium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.

Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family.

AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.

AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process.

Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process.

AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process.

Pyruvate kinase activity; potassium ion binding; magnesium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process.

AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.

AT14039p; Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: glycolytic process; pyruvate biosynthetic process.

Pyruvate kinase (PyK) encodes an enzyme involved in muscle development, glycolysis and glucose homeostasis; Belongs to the pyruvate kinase family.

Calcium ion binding; unfolded protein binding. It is involved in the biological process described with: protein folding; endoplasmic reticulum unfolded protein response.

RAC serine/threonine-protein kinase; Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. M [...]

Calcium ion binding; unfolded protein binding. It is involved in the biological process described with: protein folding; endoplasmic reticulum unfolded protein response.

Calnexin 14D; Calcium ion binding; unfolded protein binding. It is involved in the biological process described with: endoplasmic reticulum unfolded protein response; protein folding.

Pyruvate kinase activity; magnesium ion binding; potassium ion binding. It is involved in the biological process described with: pyruvate metabolic process; glycolytic process.

Uncharacterized protein; Potassium ion binding; magnesium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process.