node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG10694 | CG31528 | FBpp0083927 | FBpp0078563 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | FI07626p; Polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process. | 0.679 |
CG10694 | CG8209 | FBpp0083927 | FBpp0076470 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | GM09977p; Nucleic acid binding. | 0.593 |
CG10694 | Rad23 | FBpp0083927 | FBpp0305835 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.923 |
CG10694 | Ubqn | FBpp0083927 | FBpp0309477 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | Ubiquilin, isoform A; Ubiquilin (Ubqn) encodes a protein containing an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. It binds and delivers ubiquitinated, misfolded or no longer functionally required proteins to the ubiquitin-proteasome system and/or autophagy. | 0.814 |
CG10694 | Usp5 | FBpp0083927 | FBpp0072976 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | Ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific protease 5 (Usp5) encodes an essential enzyme that cleaves unanchored lysine48-linked polyubiquitin chains. It is involved in photoreceptor differentiation, neuron pathfinding and apoptosis. | 0.593 |
CG10694 | rngo | FBpp0083927 | FBpp0310006 | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | Rings lost (rngo) encodes a ubiquitin receptor that binds to ubiquitinated proteins via its ubiquitin-associated domain. It is an essential protein that is required for proper development of ring canals in the female germ line. | 0.731 |
CG13604 | Cbl | FBpp0303396 | FBpp0076342 | Protein UBASH3A homolog; Phosphatase activity. It is involved in the biological process described with: dephosphorylation. | Cbl proto-oncogene (Cbl) encodes an E3 protein-ubiquitin ligase for protein post-translational modification in RTK signaling (EGFR, VEGFR, FGF, and RET families) and non-RTK signaling (Src family). After the ubiquitination mediated by the product of Cbl, the substrates will be targeted to protein degradation for controlling cell growth, survival, migration and inflammation. | 0.471 |
CG15445 | Rad23 | FBpp0302762 | FBpp0305835 | LD38858p; It is involved in the biological process described with: regulation of ubiquitin-dependent protein catabolic process. | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.481 |
CG31528 | CG10694 | FBpp0078563 | FBpp0083927 | FI07626p; Polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process. | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | 0.679 |
CG31528 | Cbl | FBpp0078563 | FBpp0076342 | FI07626p; Polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process. | Cbl proto-oncogene (Cbl) encodes an E3 protein-ubiquitin ligase for protein post-translational modification in RTK signaling (EGFR, VEGFR, FGF, and RET families) and non-RTK signaling (Src family). After the ubiquitination mediated by the product of Cbl, the substrates will be targeted to protein degradation for controlling cell growth, survival, migration and inflammation. | 0.564 |
CG31528 | Rad23 | FBpp0078563 | FBpp0305835 | FI07626p; Polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process. | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.821 |
CG31528 | Ubqn | FBpp0078563 | FBpp0309477 | FI07626p; Polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process. | Ubiquilin, isoform A; Ubiquilin (Ubqn) encodes a protein containing an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. It binds and delivers ubiquitinated, misfolded or no longer functionally required proteins to the ubiquitin-proteasome system and/or autophagy. | 0.922 |
CG31528 | Usp5 | FBpp0078563 | FBpp0072976 | FI07626p; Polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process. | Ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific protease 5 (Usp5) encodes an essential enzyme that cleaves unanchored lysine48-linked polyubiquitin chains. It is involved in photoreceptor differentiation, neuron pathfinding and apoptosis. | 0.645 |
CG31528 | rngo | FBpp0078563 | FBpp0310006 | FI07626p; Polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process. | Rings lost (rngo) encodes a ubiquitin receptor that binds to ubiquitinated proteins via its ubiquitin-associated domain. It is an essential protein that is required for proper development of ring canals in the female germ line. | 0.492 |
CG8209 | CG10694 | FBpp0076470 | FBpp0083927 | GM09977p; Nucleic acid binding. | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | 0.593 |
CG8209 | Rad23 | FBpp0076470 | FBpp0305835 | GM09977p; Nucleic acid binding. | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | 0.593 |
Cbl | CG13604 | FBpp0076342 | FBpp0303396 | Cbl proto-oncogene (Cbl) encodes an E3 protein-ubiquitin ligase for protein post-translational modification in RTK signaling (EGFR, VEGFR, FGF, and RET families) and non-RTK signaling (Src family). After the ubiquitination mediated by the product of Cbl, the substrates will be targeted to protein degradation for controlling cell growth, survival, migration and inflammation. | Protein UBASH3A homolog; Phosphatase activity. It is involved in the biological process described with: dephosphorylation. | 0.471 |
Cbl | CG31528 | FBpp0076342 | FBpp0078563 | Cbl proto-oncogene (Cbl) encodes an E3 protein-ubiquitin ligase for protein post-translational modification in RTK signaling (EGFR, VEGFR, FGF, and RET families) and non-RTK signaling (Src family). After the ubiquitination mediated by the product of Cbl, the substrates will be targeted to protein degradation for controlling cell growth, survival, migration and inflammation. | FI07626p; Polyubiquitin modification-dependent protein binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process. | 0.564 |
Cbl | Ubqn | FBpp0076342 | FBpp0309477 | Cbl proto-oncogene (Cbl) encodes an E3 protein-ubiquitin ligase for protein post-translational modification in RTK signaling (EGFR, VEGFR, FGF, and RET families) and non-RTK signaling (Src family). After the ubiquitination mediated by the product of Cbl, the substrates will be targeted to protein degradation for controlling cell growth, survival, migration and inflammation. | Ubiquilin, isoform A; Ubiquilin (Ubqn) encodes a protein containing an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. It binds and delivers ubiquitinated, misfolded or no longer functionally required proteins to the ubiquitin-proteasome system and/or autophagy. | 0.564 |
Rad23 | CG10694 | FBpp0305835 | FBpp0083927 | DNA repair protein Rad23; Rad23 (Rad23) encodes an evolutionarily conserved member of the proteasome-associated proteins. It acts as a shuttle -or bridge- protein helping ubiquitinated proteins to interact with the proteasome, which in turn regulates their turnover. | AT15685p; Ubiquitin binding; polyubiquitin modification-dependent protein binding; damaged DNA binding; proteasome binding. It is involved in the biological process described with: nucleotide-excision repair; proteasome-mediated ubiquitin-dependent protein catabolic process. | 0.923 |