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| VhaAC39-1 | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa) | ||||
| ND-ASHI | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa) | ||||
| ND-75 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By sim [...] (731 aa) | ||||
| ND-B14.7 | NADH dehydrogenase (Ubiquinone) B14.7 subunit; It is involved in the biological process described with: mitochondrial respiratory chain complex I assembly. (170 aa) | ||||
| blw | ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (552 aa) | ||||
| levy | Levy, isoform A; Cytochrome-c oxidase activity; enzyme regulator activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; determination of adult lifespan; regulation of catalytic activity; aerobic respiration. (109 aa) | ||||
| CG3803 | RE54691p; Oxidoreductase activity, acting on the CH-CH group of donors; oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. It is involved in the biological process described with: oxidation-reduction process; heme A biosynthetic process. (393 aa) | ||||
| ND-19 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa) | ||||
| ATPsynF | Putative ATP synthase subunit f, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of [...] (107 aa) | ||||
| Nurf-38 | Inorganic pyrophosphatase; Component of NURF (nucleosome remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. NURF is required for homeotic gene expression, proper larval blood cell development, normal male X chromosome morphology, ecdysteroid signaling and metamorphosis. Nurf-38 may have adapted to deliver pyrophosphatase to chromatin to assist in replication or transcription by efficient removal of the inhibitory metabolite; Belongs to the PPase family. (338 aa) | ||||
| ND-30 | NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: oxidation-reduction process; reactive oxygen species metabolic process; Belongs to the complex I 30 kDa subunit family. (265 aa) | ||||
| VhaM9.7-c | V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (84 aa) | ||||
| CG9065 | LP17418p; Copper chaperone activity. It is involved in the biological process described with: copper ion transport; respiratory chain complex IV assembly; mitochondrial cytochrome c oxidase assembly. (88 aa) | ||||
| sun | Protein stunted; Activates the G-protein coupled receptor mth in vitro, leading to increased intracellular calcium ion levels. (61 aa) | ||||
| UQCR-14 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa) | ||||
| ND-24 | NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; respiratory electron transport chain. (242 aa) | ||||
| ND-18 | NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: electron transport chain; mitochondrial respiratory chain complex I assembly. (183 aa) | ||||
| COX6B | Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (96 aa) | ||||
| ND-24L | NADH dehydrogenase (Ubiquinone) 24 kDa subunit-like; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; respiratory electron transport chain. (238 aa) | ||||
| UQCR-C2 | Endopeptidase activity; metal ion binding; ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; protein processing involved in protein targeting to mitochondrion. (440 aa) | ||||
| ATPsynbetaL | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (622 aa) | ||||
| ND-SGDH | NADH dehydrogenase (ubiquinone) SGDH subunit (ND-SGDH) encodes a protein required for proper mitochondrial electron transport chain function. It is involved in longevity and redox response. (186 aa) | ||||
| SdhAL | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (651 aa) | ||||
| Vha16-2 | V-type proton ATPase proteolipid subunit; Vacuolar H[+] ATPase 16kD subunit 2 (Vha16-2) encodes the main subunit of the membrane-embedded V0 sector of the vacuolar-ATPase, which is responsible for acidification of the endo-lysosomal lumen and other cellular compartment. As part of the V-ATPase, the product of Vha16-2 supports membrane trafficking, protein degradation and multiple associated signaling pathways, such as mTor, Wnt and Notch. (158 aa) | ||||
| ND-13B | NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; respiratory electron transport chain. (124 aa) | ||||
| ATPsynB | ATP synthase subunit b, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (243 aa) | ||||
| Cyt-c1 | Cytochrome c1, isoform A; Heme binding; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial ATP synthesis coupled proton transport. (307 aa) | ||||
| ND-B8 | NADH dehydrogenase (Ubiquinone) B8 subunit; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (95 aa) | ||||
| ND-PDSW | NADH dehydrogenase (Ubiquinone) PDSW subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (159 aa) | ||||
| ND-39 | NADH dehydrogenase (ubiquinone) 39 kDa subunit (ND-39) encodes a subunit of mitochondrial respiratory complex I (cI, NADH:ubiquinone oxidoreductase). (416 aa) | ||||
| ND-B14.5AL | NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (145 aa) | ||||
| Vha14-2 | Probable V-type proton ATPase subunit F 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (129 aa) | ||||
| CG31648 | RE57459p; Copper ion binding. It is involved in the biological process described with: aerobic respiration; respiratory chain complex IV assembly. (241 aa) | ||||
| ND-51 | NADH dehydrogenase (ubiquinone) 51 kDa subunit (ND-51) encodes a flavoprotein and iron-sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. It is a component of the mitochondrial electron transport complex I, which is part of the oxidative phosphorylation pathway. It may have a role in regulating aggression behavior. (474 aa) | ||||
| COX5B | Cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; mitochondrial ATP synthesis coupled proton transport. (120 aa) | ||||
| COX5BL | Cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; mitochondrial ATP synthesis coupled proton transport. (154 aa) | ||||
| ATPsynGL | ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (107 aa) | ||||
| CG5037 | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (391 aa) | ||||
| Vha16-5 | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (193 aa) | ||||
| Vha68-2 | Vacuolar H[+] ATPase 68 kDa subunit 2 (Vha68-2) encodes a component of the V1 subunit of the vacuolar ATPase, which acidifies endosomal compartments including the lysosome and influences the activity of several signaling pathways. (614 aa) | ||||
| Vha68-3 | Vacuolar H[+] ATPase 68kD subunit 3; ATP binding; proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: proton transmembrane transport; ATP metabolic process. (743 aa) | ||||
| Vha68-1 | V-type proton ATPase catalytic subunit A isoform 1; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (614 aa) | ||||
| ND-B22 | NADH dehydrogenase (Ubiquinone) B22 subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (144 aa) | ||||
| COX7AL | Cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial respirasome assembly; regulation of oxidative phosphorylation; mitochondrial electron transport, cytochrome c to oxygen. (106 aa) | ||||
| CG6629 | AT18465p; Succinate dehydrogenase activity. It is involved in the biological process described with: tricarboxylic acid cycle; mitochondrial electron transport, succinate to ubiquinone. (261 aa) | ||||
| COX5A | Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (149 aa) | ||||
| Vha55 | V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. (490 aa) | ||||
| VhaPPA1-1 | Vacuolar H[+] ATPase PPA1 subunit 1 (VhaPPA1-1) encodes a protein involved in tracheal terminal branching; Belongs to the V-ATPase proteolipid subunit family. (212 aa) | ||||
| ATPsynO | ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (209 aa) | ||||
| ND-23 | NADH dehydrogenase (Ubiquinone) 23 kDa subunit; NADH dehydrogenase activity; 4 iron, 4 sulfur cluster binding. It is involved in the biological process described with: aerobic respiration; mitochondrial ATP synthesis coupled electron transport; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly. (217 aa) | ||||
| VhaM9.7-d | V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (88 aa) | ||||
| Vha100-2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa) | ||||
| Vha100-4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (844 aa) | ||||
| NP15.6 | GEO04710p1; It is involved in the biological process described with: respiratory electron transport chain. (150 aa) | ||||
| ND-42 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (407 aa) | ||||
| VhaAC39-2 | Probable V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system; Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa) | ||||
| SdhD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (182 aa) | ||||
| UQCR-14L | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa) | ||||
| Cyt-c1L | Cytochrome c1-like; Heme binding; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial ATP synthesis coupled proton transport. (344 aa) | ||||
| ATPsyngamma | ATP synthase subunit gamma, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (297 aa) | ||||
| ATPsynC | ATP synthase, subunit C, isoform A; Proton-transporting ATP synthase activity, rotational mechanism. It is involved in the biological process described with: ATP synthesis coupled proton transport; proton transmembrane transport. (138 aa) | ||||
| COX4L | Cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen. (176 aa) | ||||
| Vha16-1 | Vacuolar H[+] ATPase 16kD subunit 1 (Vha16-1) encodes the proteolipid component of V-ATPase, which is a multi-functional channel protein. It contributes to vesicle-membrane fusion, hydrophilic molecule transport and intercellular communication. (159 aa) | ||||
| SdhB | Succinate dehydrogenase, subunit B (iron-sulfur) (SdhB) encodes the iron-sulfur cluster-containing subunit of the succinate dehydrogenase complex, which oxidizes succinate to fumarate and passes the electrons to quinones. The redox-active cofactors in this subunit are part of the electron transfer machinery in the complex; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (297 aa) | ||||
| SdhA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Maintaining electron transport chain function is required to prevent neurodegenerative changes seen in both early- and late-onset disorders. (661 aa) | ||||
| Vha100-3 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (904 aa) | ||||
| ND-51L1 | NADH dehydrogenase (Ubiquinone) 51 kDa subunit-like 1; 4 iron, 4 sulfur cluster binding; NADH dehydrogenase (ubiquinone) activity; FMN binding; NAD binding. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (702 aa) | ||||
| Vha16-4 | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa) | ||||
| COX6AL | Cytochrome-c oxidase activity; enzyme regulator activity. It is involved in the biological process described with: aerobic respiration; mitochondrial electron transport, cytochrome c to oxygen. (94 aa) | ||||
| Vha36-1 | V-type proton ATPase subunit D 1; Subunit of the peripheral V1 complex of vacuolar ATPase. V- ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity); Belongs to the V-ATPase D subunit family. (246 aa) | ||||
| Vha14-1 | V-type proton ATPase subunit F 1; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa) | ||||
| ND-51L2 | NADH dehydrogenase (Ubiquinone) 51 kDa subunit-like 2, isoform A; 4 iron, 4 sulfur cluster binding; NADH dehydrogenase activity; NAD binding; FMN binding. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; multicellular organism reproduction. (481 aa) | ||||
| ND-B15 | NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (113 aa) | ||||
| ox | Cytochrome b-c1 complex subunit 9; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inn [...] (55 aa) | ||||
| Vha36-2 | Vacuolar H[+] ATPase 36kD subunit 2; Proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: proton transmembrane transport. (373 aa) | ||||
| VhaAC45 | V-type proton ATPase subunit S1; Accessory subunit of the proton-transporting vacuolar (V)- ATPase protein pump, which is required for luminal acidification of secretory vesicles. (379 aa) | ||||
| mt:ND2 | NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (341 aa) | ||||
| mt:CoI | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (511 aa) | ||||
| mt:CoII | Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (228 aa) | ||||
| mt:ATPase8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (53 aa) | ||||
| mt:CoIII | Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (262 aa) | ||||
| mt:ND3 | NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (117 aa) | ||||
| mt:ND4L | NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (96 aa) | ||||
| mt:ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (174 aa) | ||||
| ND-MWFE | NADH dehydrogenase (Ubiquinone) MWFE subunit, isoform B. (123 aa) | ||||
| VhaM9.7-a | V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (85 aa) | ||||
| ATPsynepsilonL | ATP synthase, epsilon subunit-like, isoform A; Proton-transporting ATP synthase activity, rotational mechanism; ATPase activity. It is involved in the biological process described with: ATP synthesis coupled proton transport; proton transmembrane transport. (64 aa) | ||||
| ND-AGGG | NADH dehydrogenase (Ubiquinone) AGGG subunit, isoform A. (94 aa) | ||||
| ND-49L | NADH dehydrogenase activity; quinone binding; NADH dehydrogenase (ubiquinone) activity; NAD binding. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; Belongs to the complex I 49 kDa subunit family. (523 aa) | ||||
| VhaPPA1-2 | Vacuolar H[+] ATPase PPA1 subunit 2; Proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: proton transmembrane transport; Belongs to the V-ATPase proteolipid subunit family. (212 aa) | ||||
| Vha44 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (836 aa) | ||||
| CG14077 | IP09469p1; Cytochrome-c oxidase activity; enzyme regulator activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen; aerobic respiration. (289 aa) | ||||
| ND-B12 | NADH dehydrogenase (Ubiquinone) B12 subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial respiratory chain complex I assembly; mitochondrial electron transport, NADH to ubiquinone. (110 aa) | ||||
| ND-MNLL | NADH dehydrogenase (Ubiquinone) MNLL subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (56 aa) | ||||
| UQCR-11 | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (85 aa) | ||||
| Vha16-3 | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa) | ||||
| UQCR-Q | Ubiquinol-cytochrome-c reductase activity; ubiquinone binding. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c. (89 aa) | ||||
| ATPsynE | ATP synthase, subunit E, isoform A; Proton transmembrane transporter activity. It is involved in the biological process described with: proton transmembrane transport; ATP synthesis coupled proton transport. (81 aa) | ||||
| COX7A | Cytochrome c oxidase subunit 7A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (98 aa) | ||||
| ATPsynCF6 | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of t [...] (106 aa) | ||||
| ATPsynG | ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (99 aa) | ||||
| CG43206 | Uncharacterized protein; Ubiquinol-cytochrome-c reductase activity. (72 aa) | ||||
| cype | Cyclope (cype) encodes a cytochrome c oxidase subunit VIc homolog acting as an enhancer of dpp pathway phenotypes. It is involved in hair and cell growth and in ommatidia development. (77 aa) | ||||
| CG15719 | GEO02534p1; ATPase-coupled ion transmembrane transporter activity. It is involved in the biological process described with: ion transmembrane transport. (160 aa) | ||||
| UQCR-6.4 | Ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c. (57 aa) | ||||
| ND-B14.5B | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (116 aa) | ||||
| ND-15 | NADH dehydrogenase (Ubiquinone) 15 kDa subunit, isoform A; It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (101 aa) | ||||
| ND-MLRQ | NADH dehydrogenase (Ubiquinone) MLRQ subunit, isoform A; Cytochrome-c oxidase activity; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (83 aa) | ||||
| ND-B14 | NADH dehydrogenase (Ubiquinone) B14 subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; response to oxidative stress; Belongs to the complex I LYR family. (124 aa) | ||||
| COX4 | Cytochrome c oxidase subunit 4 (COX4) encodes a subunit of the cytochrome-c oxidase. It is involved in cell proliferation and golgi structural organisation. (182 aa) | ||||
| UQCR-11L | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (86 aa) | ||||
| VhaM9.7-b | V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (89 aa) | ||||
| COX8 | Cytochrome-c oxidase activity. (68 aa) | ||||
| ATPsynbeta | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (511 aa) | ||||
| ND-49 | NADH dehydrogenase (ubiquinone) activity; quinone binding; NAD binding; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; Belongs to the complex I 49 kDa subunit family. (468 aa) | ||||
| RFeSP | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (230 aa) | ||||
| ND-B17.2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (142 aa) | ||||
| SdhC | Succinate dehydrogenase, subunit C (SdhC) encodes a protein involved in mitochondrial electron transport and oxidative stress response. (171 aa) | ||||
| Vha100-5 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (814 aa) | ||||
| COX7C | Cytochrome c oxidase subunit 7C (COX7C) encodes a negative regulator of neuroblast proliferation. (66 aa) | ||||
| CG44296 | Uncharacterized protein; Cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen. (76 aa) | ||||
| ND-20L | NADH dehydrogenase (ubiquinone) 20 kDa subunit-like (ND-20L) encodes a flavoprotein and iron-sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. It is a component of the mitochondrial electron transport complex I, which is part of the oxidative phosphorylation pathway. It may have a role in regulating aggression behavior. (212 aa) | ||||
| ND-20 | NADH dehydrogenase (ubiquinone) 20 kDa subunit (ND-20) encodes a component of the mitochondrial electron transport chain and is involved in determination of life span. (221 aa) | ||||
| ND-B18 | NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (117 aa) | ||||
| CG31644 | Uncharacterized protein, isoform C; Cytochrome-c oxidase activity. (90 aa) | ||||
| ND-B14.5A | NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (103 aa) | ||||
| ND-B17 | NADH dehydrogenase (Ubiquinone) B17 subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (167 aa) | ||||
| ATPsyndelta | ATP synthase, delta subunit, isoform A; Proton-transporting ATP synthase activity, rotational mechanism. It is involved in the biological process described with: ATP synthesis coupled proton transport; proton transmembrane transport. (157 aa) | ||||
| SdhBL | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (437 aa) | ||||
| ND-13A | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (126 aa) | ||||
| Vha36-3 | Probable V-type proton ATPase subunit D 2; Subunit of the peripheral V1 complex of vacuolar ATPase. V- ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity); Belongs to the V-ATPase D subunit family. (249 aa) | ||||
| Vha13 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (117 aa) | ||||
| Vha26 | V-type proton ATPase subunit E; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (226 aa) | ||||
| ATPsynD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (178 aa) | ||||
| ND-B16.6 | NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. (154 aa) | ||||
| mt:ATPase6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (224 aa) | ||||
| mt:ND1 | NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (312 aa) | ||||
| mt:ND4 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (446 aa) | ||||
| mt:ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (572 aa) | ||||
| mt:Cyt-b | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (378 aa) | ||||