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CG4586 CG4586 spidey spidey Acox57D-p Acox57D-p Acox57D-d Acox57D-d Sc2 Sc2 Mfe2 Mfe2 Baldspot Baldspot Fad2 Fad2 Elo68alpha Elo68alpha Hacd1 Hacd1 Hacd2 Hacd2 ScpX ScpX CG17544 CG17544 Desat2 Desat2 Desat1 Desat1 CG8630 CG8630 CG9743 CG9743 CG15531 CG15531 CG17821 CG17821 CG18609 CG18609 CG5009 CG5009 Elo68beta Elo68beta CG9527 CG9527 CG17597 CG17597 CG9747 CG9747
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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textmining
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CG4586Acyl-coenzyme A oxidase; Flavin adenine dinucleotide binding; FAD binding; fatty acid binding; acyl-CoA oxidase activity. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase. (677 aa)
spideyRH59310p; Spidey (spidey) encodes a member of the short chain dehydrogenase/reductase family. It regulates oenocyte growth and maturation, as well as the metabolism of ecdysteroids and cuticular hydrocarbons; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (321 aa)
Acox57D-pAcyl-coenzyme A oxidase; Flavin adenine dinucleotide binding; acyl-CoA oxidase activity; FAD binding; fatty acid binding. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase. (677 aa)
Acox57D-dAcyl-coenzyme A oxidase; FAD binding; fatty acid binding; acyl-CoA oxidase activity; flavin adenine dinucleotide binding. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase. (677 aa)
Sc2Sc2; Oxidoreductase activity; oxidoreductase activity, acting on the CH-CH group of donors. It is involved in the biological process described with: very long-chain fatty acid biosynthetic process. (302 aa)
Mfe2Peroxisomal Multifunctional enzyme type 2 (Mfe2) encodes a multifunctional protein harboring two separate enzyme activities: 2-enoyl-CoA hydratase 2 and 3-hydroxyacyl-CoA dehydrogenase. They function in the peroxisomal fatty acid breakdown spiral of beta-oxidation utilizing the (R)-isomer of the CoA-containing substrate; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (598 aa)
BaldspotElongation of very long chain fatty acids protein; Baldspot (Baldspot) encodes a protein involved in spermatogenesis. (316 aa)
Fad2Fad2 (Fad2) encodes a transmembrane fatty acid desaturase that utilizes mono-unsaturated long-chain fatty acids (LCFAs) to synthesize di-unsaturated LCFAs. It is involved in the synthesis of the female pheromones. (355 aa)
Elo68alphaElongation of very long chain fatty acids protein; Elongase 68alpha (Elo68alpha) encodes a transmembrane fatty acid elongase, elongating Delta9 unsaturated LCFAs (C14 and C16) to Delta11 LCFAs (C16 and C18), that is involved in the synthesis of the male pheromone cis-vaccenyl acetate. (262 aa)
Hacd1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (245 aa)
Hacd2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (371 aa)
ScpXSterol carrier protein X-related thiolase; Transferase activity, transferring acyl groups other than amino-acyl groups; phospholipid transporter activity. It is involved in the biological process described with: positive regulation of intracellular cholesterol transport; phospholipid transport; Belongs to the thiolase-like superfamily. Thiolase family. (544 aa)
CG17544acyl-CoA oxidase activity; fatty acid binding; FAD binding; flavin adenine dinucleotide binding; pristanoyl-CoA oxidase activity. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase. (693 aa)
Desat2Fatty acid desaturase 2; stearoyl-CoA 9-desaturase activity; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; unsaturated fatty acid biosynthetic process; Belongs to the fatty acid desaturase type 1 family. (361 aa)
Desat1Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids. (383 aa)
CG8630RE43130p; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: lipid metabolic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (408 aa)
CG9743RH14937p; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (420 aa)
CG15531FA_desaturase domain-containing protein; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (334 aa)
CG17821Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (262 aa)
CG18609Elongation of very long chain fatty acids protein; Fatty acid elongase activity. (263 aa)
CG5009Probable peroxisomal acyl-coenzyme A oxidase 1; Flavin adenine dinucleotide binding; fatty acid binding; FAD binding; acyl-CoA oxidase activity; Belongs to the acyl-CoA oxidase family. (669 aa)
Elo68betaElongation of very long chain fatty acids protein; Fatty acid elongase activity. (269 aa)
CG9527Acyl-coenzyme A oxidase; Fatty acid binding; FAD binding; acyl-CoA oxidase activity; pristanoyl-CoA oxidase activity; flavin adenine dinucleotide binding. It is involved in the biological process described with: lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid beta-oxidation. (724 aa)
CG17597SD06839p; Transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with: positive regulation of intracellular cholesterol transport; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
CG9747GH07782p; Iron ion binding; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with: unsaturated fatty acid biosynthetic process; oxidation-reduction process; Belongs to the fatty acid desaturase type 1 family. (461 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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