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SrpRalpha | Signal recognition particle receptor subunit alpha homolog; Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity). May have a role in axonogenesis. (614 aa) | ||||
Hsc70-3 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity). Acts as a key repressor of the unfolded protein response (UPR) (By similarity). (656 aa) | ||||
CG9240 | Mitochondrial inner membrane protease subunit; Serine-type peptidase activity. It is involved in the biological process described with: protein processing involved in protein targeting to mitochondrion. (166 aa) | ||||
OXA1L | OXA1L mitochondrial inner membrane protein, isoform A; Membrane insertase activity. It is involved in the biological process described with: protein insertion into mitochondrial inner membrane from matrix; mitochondrial cytochrome c oxidase assembly; respiratory chain complex IV assembly; protein insertion into membrane. (441 aa) | ||||
Srp68 | Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Srp68 binds the 7S RNA, Srp72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function (By similarity). (604 aa) | ||||
Srp9 | Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Srp9 together with Srp14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of Srp9 and Srp14 is required for SRP RNA binding (By similarity). (77 aa) | ||||
Sec63 | Secretory 63; Protein transmembrane transporter activity; RNA binding. It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane; posttranslational protein targeting to endoplasmic reticulum membrane; posttranslational protein targeting to membrane, translocation. (753 aa) | ||||
Srp19 | Signal recognition particle 19 kDa protein; Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (160 aa) | ||||
Srp54k | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (508 aa) | ||||
Trp1 | Translocation protein 1, isoform B; Protein transmembrane transporter activity. It is involved in the biological process described with: posttranslational protein targeting to membrane, translocation. (428 aa) | ||||
twr | Signal peptidase complex catalytic subunit SEC11; Serine-type peptidase activity; peptidase activity. It is involved in the biological process described with: signal peptide processing. (185 aa) | ||||
Srp72 | Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (650 aa) | ||||
Spase12 | Signal peptidase complex subunit 1; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (98 aa) | ||||
CG11110 | IP06605p; Serine-type peptidase activity. It is involved in the biological process described with: signal peptide processing; protein processing involved in protein targeting to mitochondrion; mitochondrial respiratory chain complex assembly. (171 aa) | ||||
CG13426 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity; protein transmembrane transporter activity. It is involved in the biological process described with: posttranslational protein targeting to membrane, translocation. (105 aa) | ||||
Sec61beta | Sec61 beta subunit (Sec61beta) encodes a protein involved in the regulation of autophagy. (100 aa) | ||||
CG8860 | Protein transport protein Sec61 gamma-1 subunit; Necessary for protein translocation in the endoplasmic reticulum. (68 aa) | ||||
Srp14 | Signal recognition particle protein 14; Endoplasmic reticulum signal peptide binding; 7S RNA binding. It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane; protein targeting to ER. (109 aa) | ||||
Spase22-23 | Signal peptidase complex subunit 3; Component of the microsomal signal peptidase complex which removes signal peptides and other N-terminal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (179 aa) | ||||
SrpRbeta | Signal recognition particle receptor beta (SrpRbeta) encodes a protein that contributes to cuticle secretion by epidermal cells. (244 aa) | ||||
Spase25 | Signal peptidase complex subunit 2; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (199 aa) | ||||
Sec61gamma | Protein transport protein Sec61 gamma-2 subunit; Necessary for protein translocation in the endoplasmic reticulum. (68 aa) | ||||
Sec61alpha | Sec61 alpha subunit (Sec61alpha) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel. (476 aa) |