(62 nodes) Spliceosomal snRNP complex, and Spliceosome network (Drosophila navojoa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AWZ03_014619	Uncharacterized protein. (988 aa)
	AWZ03_015137	Uncharacterized protein. (40 aa)
	AWZ03_014102	Uncharacterized protein. (494 aa)
	AWZ03_013576	Uncharacterized protein. (1232 aa)
	AWZ03_013057	Small nuclear ribonucleoprotein G. (76 aa)
	AWZ03_012421	Uncharacterized protein. (552 aa)
	AWZ03_012668	Uncharacterized protein. (791 aa)
	AWZ03_012465	Uncharacterized protein. (1014 aa)
	AWZ03_012087	Matrin-type domain-containing protein. (503 aa)
	AWZ03_011467	Uncharacterized protein. (906 aa)
	AWZ03_010455	Uncharacterized protein. (340 aa)
	AWZ03_010311	Uncharacterized protein. (216 aa)
	AWZ03_009964	Uncharacterized protein. (187 aa)
	AWZ03_010317	RRM domain-containing protein. (789 aa)
	AWZ03_010165	Uncharacterized protein. (1933 aa)
	AWZ03_009243	Uncharacterized protein. (985 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (137 aa)
	AWZ03_009090	WD_REPEATS_REGION domain-containing protein. (347 aa)
	AWZ03_008717	Uncharacterized protein. (110 aa)
	AWZ03_008199	Sm domain-containing protein. (110 aa)
	AWZ03_008826	Uncharacterized protein. (971 aa)
	AWZ03_008081	U1-type domain-containing protein. (195 aa)
	AWZ03_008010	Nop domain-containing protein. (503 aa)
	AWZ03_007608	Sm domain-containing protein. (124 aa)
	AWZ03_007007	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	AWZ03_007680	RRM domain-containing protein. (452 aa)
	AWZ03_006545	Uncharacterized protein. (250 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (154 aa)
	AWZ03_005621	Sm domain-containing protein. (191 aa)
	AWZ03_005373	Small nuclear ribonucleoprotein Sm D2. (124 aa)
	AWZ03_006308	Small nuclear ribonucleoprotein-associated protein. (198 aa)
	AWZ03_006224	Uncharacterized protein. (616 aa)
	AWZ03_005703	Uncharacterized protein. (644 aa)
	AWZ03_005744	Uncharacterized protein. (837 aa)
	AWZ03_004835	WD_REPEATS_REGION domain-containing protein. (445 aa)
	AWZ03_004750	Uncharacterized protein. (548 aa)
	AWZ03_004358	Uncharacterized protein. (509 aa)
	AWZ03_004058	Uncharacterized protein. (1135 aa)
	AWZ03_004676	PRP38_assoc domain-containing protein. (365 aa)
	AWZ03_003906	Uncharacterized protein. (606 aa)
	AWZ03_003635	Uncharacterized protein. (352 aa)
	AWZ03_004679	Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (79 aa)
	AWZ03_003664	TOG domain-containing protein. (1332 aa)
	AWZ03_004115	PSP domain-containing protein. (744 aa)
	snRNP-U1-C	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family. (144 aa)
	AWZ03_003389	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (183 aa)
	AWZ03_003880	Matrin-type domain-containing protein. (260 aa)
	AWZ03_004330	Tr-type G domain-containing protein. (976 aa)
	AWZ03_003198	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (124 aa)
	AWZ03_003252	CPSF_A domain-containing protein. (1229 aa)
	AWZ03_003320	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	AWZ03_002994	Uncharacterized protein. (936 aa)
	AWZ03_002443	Uncharacterized protein. (1744 aa)
	AWZ03_001896	Small nuclear ribonucleoprotein Sm D3. (151 aa)
	AWZ03_001543	CCHC-type domain-containing protein. (766 aa)
	AWZ03_001892	MPN domain-containing protein. (2397 aa)
	AWZ03_000739	RRM domain-containing protein. (121 aa)
	AWZ03_000214	Protein kinase domain-containing protein. (932 aa)
	AWZ03_000825	Uncharacterized protein; Belongs to the DEAD box helicase family. (795 aa)
	AWZ03_000905	MFAP1 domain-containing protein. (473 aa)
	AWZ03_000698	WD_REPEATS_REGION domain-containing protein. (540 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)

Your Current Organism:

Drosophila navojoa

NCBI taxonomy Id: 7232
Other names: D. navojoa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AWZ03_000214	AWZ03_000698	A0A484BX47	A0A484C013	Protein kinase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.837
AWZ03_000214	AWZ03_000905	A0A484BX47	A0A484BXE1	Protein kinase domain-containing protein.	MFAP1 domain-containing protein.	0.422
AWZ03_000214	AWZ03_001892	A0A484BX47	A0A484BUC8	Protein kinase domain-containing protein.	MPN domain-containing protein.	0.886
AWZ03_000214	AWZ03_001896	A0A484BX47	A0A484BSP6	Protein kinase domain-containing protein.	Small nuclear ribonucleoprotein Sm D3.	0.536
AWZ03_000214	AWZ03_002443	A0A484BX47	A0A484BSL3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.503
AWZ03_000214	AWZ03_002994	A0A484BX47	A0A484BRJ8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.735
AWZ03_000214	AWZ03_003198	A0A484BX47	A0A484BNF0	Protein kinase domain-containing protein.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.745
AWZ03_000214	AWZ03_003252	A0A484BX47	A0A484BNJ8	Protein kinase domain-containing protein.	CPSF_A domain-containing protein.	0.723
AWZ03_000214	AWZ03_003320	A0A484BX47	A0A484BRD5	Protein kinase domain-containing protein.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.531
AWZ03_000214	AWZ03_003664	A0A484BX47	A0A484BMC6	Protein kinase domain-containing protein.	TOG domain-containing protein.	0.871
AWZ03_000214	AWZ03_003880	A0A484BX47	A0A484BN75	Protein kinase domain-containing protein.	Matrin-type domain-containing protein.	0.536
AWZ03_000214	AWZ03_003906	A0A484BX47	A0A484BLQ7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.706
AWZ03_000214	AWZ03_004058	A0A484BX47	A0A484BL98	Protein kinase domain-containing protein.	Uncharacterized protein.	0.785
AWZ03_000214	AWZ03_004115	A0A484BX47	A0A484BML6	Protein kinase domain-containing protein.	PSP domain-containing protein.	0.660
AWZ03_000214	AWZ03_004330	A0A484BX47	A0A484BND6	Protein kinase domain-containing protein.	Tr-type G domain-containing protein.	0.889
AWZ03_000214	AWZ03_004358	A0A484BX47	A0A484BKB6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.636
AWZ03_000214	AWZ03_004679	A0A484BX47	A0A484BMC3	Protein kinase domain-containing protein.	Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.753
AWZ03_000214	AWZ03_004750	A0A484BX47	A0A484BJ88	Protein kinase domain-containing protein.	Uncharacterized protein.	0.536
AWZ03_000214	AWZ03_004835	A0A484BX47	A0A484BIU8	Protein kinase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.577
AWZ03_000214	AWZ03_005373	A0A484BX47	A0A484BHG4	Protein kinase domain-containing protein.	Small nuclear ribonucleoprotein Sm D2.	0.661