(123 nodes) Catalytic step 2 spliceosome network (Drosophila navojoa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AWZ03_009090	WD_REPEATS_REGION domain-containing protein. (347 aa)
	AWZ03_005621	Sm domain-containing protein. (191 aa)
	AWZ03_006522	Uncharacterized protein. (537 aa)
	AWZ03_005373	Small nuclear ribonucleoprotein Sm D2. (124 aa)
	AWZ03_006288	Uncharacterized protein; Belongs to the argonaute family. (854 aa)
	AWZ03_010641	Uncharacterized protein. (625 aa)
	AWZ03_006308	Small nuclear ribonucleoprotein-associated protein. (198 aa)
	AWZ03_005999	RRM domain-containing protein. (277 aa)
	AWZ03_006224	Uncharacterized protein. (616 aa)
	AWZ03_005744	Uncharacterized protein. (837 aa)
	AWZ03_005970	Uncharacterized protein. (116 aa)
	AWZ03_005701	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
	AWZ03_005417	Metalloendopeptidase. (945 aa)
	AWZ03_004750	Uncharacterized protein. (548 aa)
	AWZ03_004459	Uncharacterized protein. (1288 aa)
	AWZ03_004306	Uncharacterized protein; Belongs to the DEAD box helicase family. (507 aa)
	AWZ03_004358	Uncharacterized protein. (509 aa)
	AWZ03_005176	Nkap_C domain-containing protein. (468 aa)
	AWZ03_004646	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (165 aa)
	AWZ03_004058	Uncharacterized protein. (1135 aa)
	AWZ03_004676	PRP38_assoc domain-containing protein. (365 aa)
	AWZ03_003926	CSD_1 domain-containing protein. (334 aa)
	AWZ03_003664	TOG domain-containing protein. (1332 aa)
	AWZ03_004115	PSP domain-containing protein. (744 aa)
	AWZ03_003880	Matrin-type domain-containing protein. (260 aa)
	AWZ03_003158	DZF domain-containing protein. (911 aa)
	AWZ03_004330	Tr-type G domain-containing protein. (976 aa)
	AWZ03_003198	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (124 aa)
	AWZ03_004350	PPIase cyclophilin-type domain-containing protein. (906 aa)
	AWZ03_004380	Uncharacterized protein. (383 aa)
	AWZ03_003252	CPSF_A domain-containing protein. (1229 aa)
	AWZ03_003426	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (388 aa)
	AWZ03_009615	PPIase cyclophilin-type domain-containing protein. (505 aa)
	AWZ03_009386	Uncharacterized protein. (599 aa)
	AWZ03_008924	Uncharacterized protein. (147 aa)
	AWZ03_008564	Uncharacterized protein. (294 aa)
	AWZ03_008717	Uncharacterized protein. (110 aa)
	AWZ03_008488	Uncharacterized protein. (246 aa)
	AWZ03_008361	Uncharacterized protein. (893 aa)
	AWZ03_008381	Uncharacterized protein. (1066 aa)
	AWZ03_008887	Uncharacterized protein. (536 aa)
	AWZ03_008843	Uncharacterized protein. (226 aa)
	AWZ03_009225	Cwf21 domain-containing protein. (169 aa)
	AWZ03_008199	Sm domain-containing protein. (110 aa)
	AWZ03_000739	RRM domain-containing protein. (121 aa)
	AWZ03_001461	Uncharacterized protein. (1181 aa)
	AWZ03_001346	Uncharacterized protein. (624 aa)
	AWZ03_001463	Aquarius_N domain-containing protein. (317 aa)
	AWZ03_000691	Uncharacterized protein. (349 aa)
	AWZ03_001105	WD_REPEATS_REGION domain-containing protein. (570 aa)
	AWZ03_000626	C2H2-type domain-containing protein. (743 aa)
	AWZ03_000214	Protein kinase domain-containing protein. (932 aa)
	AWZ03_000905	MFAP1 domain-containing protein. (473 aa)
	AWZ03_000698	WD_REPEATS_REGION domain-containing protein. (540 aa)
	AWZ03_008755	Uncharacterized protein. (533 aa)
	AWZ03_002549	KH domain-containing protein. (359 aa)
	AWZ03_011451	Uncharacterized protein. (264 aa)
	AWZ03_011664	Uncharacterized protein. (1035 aa)
	AWZ03_011975	Uncharacterized protein. (325 aa)
	AWZ03_011904	Uncharacterized protein. (222 aa)
	AWZ03_012668	Uncharacterized protein. (791 aa)
	AWZ03_012230	Uncharacterized protein. (772 aa)
	AWZ03_012588	Septin-interacting protein 1; May be involved in pre-mRNA splicing. Belongs to the TFP11/STIP family. (852 aa)
	AWZ03_012421	Uncharacterized protein. (552 aa)
	AWZ03_012473	DUF2040 domain-containing protein. (392 aa)
	AWZ03_013700	Uncharacterized protein. (255 aa)
	AWZ03_012813	RRM domain-containing protein. (183 aa)
	AWZ03_013057	Small nuclear ribonucleoprotein G. (76 aa)
	AWZ03_011833	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (303 aa)
	AWZ03_011631	Uncharacterized protein. (498 aa)
	AWZ03_012027	TPR_REGION domain-containing protein. (701 aa)
	AWZ03_011317	Uncharacterized protein. (234 aa)
	AWZ03_012087	Matrin-type domain-containing protein. (503 aa)
	AWZ03_011590	WD_REPEATS_REGION domain-containing protein. (478 aa)
	AWZ03_003320	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	AWZ03_002241	Uncharacterized protein. (648 aa)
	AWZ03_002244	Uncharacterized protein. (355 aa)
	AWZ03_001896	Small nuclear ribonucleoprotein Sm D3. (151 aa)
	AWZ03_002339	Nitric oxide synthase-interacting protein homolog. (309 aa)
	AWZ03_002454	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (645 aa)
	AWZ03_001449	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (149 aa)
	AWZ03_002514	Uncharacterized protein. (883 aa)
	AWZ03_001520	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (173 aa)
	AWZ03_002240	Uncharacterized protein. (343 aa)
	AWZ03_007654	Uncharacterized protein. (512 aa)
	AWZ03_007848	Uncharacterized protein; Belongs to the heat shock protein 70 family. (651 aa)
	AWZ03_006876	Uncharacterized protein. (685 aa)
	AWZ03_007680	RRM domain-containing protein. (452 aa)
	AWZ03_001882	Uncharacterized protein. (458 aa)
	AWZ03_001892	MPN domain-containing protein. (2397 aa)
	AWZ03_001259	Tudor domain-containing protein. (194 aa)
	AWZ03_014593	SKIP_SNW domain-containing protein. (543 aa)
	AWZ03_015137	Uncharacterized protein. (40 aa)
	AWZ03_014746	Uncharacterized protein. (163 aa)
	AWZ03_013924	GCFC domain-containing protein. (929 aa)
	AWZ03_014494	Uncharacterized protein. (483 aa)
	AWZ03_013848	C3H1-type domain-containing protein. (970 aa)
	AWZ03_013977	Uncharacterized protein. (248 aa)
	AWZ03_006530	Uncharacterized protein. (643 aa)
	AWZ03_006545	Uncharacterized protein. (250 aa)
	AWZ03_006195	Uncharacterized protein. (817 aa)
	AWZ03_007107	WD_REPEATS_REGION domain-containing protein. (308 aa)
	AWZ03_006015	RRM domain-containing protein. (302 aa)
	AWZ03_005750	Uncharacterized protein. (579 aa)
	AWZ03_009101	PWI domain-containing protein. (1095 aa)
	AWZ03_010165	Uncharacterized protein. (1933 aa)
	AWZ03_009226	Uncharacterized protein. (1614 aa)
	AWZ03_009619	G-patch domain-containing protein. (986 aa)
	AWZ03_010640	Uncharacterized protein. (428 aa)
	AWZ03_009702	Uncharacterized protein. (759 aa)
	AWZ03_010812	Uncharacterized protein. (261 aa)
	AWZ03_010396	RRM domain-containing protein. (622 aa)
	AWZ03_010722	Uncharacterized protein. (406 aa)
	AWZ03_010108	Uncharacterized protein. (272 aa)
	AWZ03_010311	Uncharacterized protein. (216 aa)
	AWZ03_010724	BTB domain-containing protein. (170 aa)
	AWZ03_011467	Uncharacterized protein. (906 aa)
	AWZ03_010535	Uncharacterized protein. (517 aa)
	AWZ03_011652	Uncharacterized protein. (144 aa)
	AWZ03_011440	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (577 aa)
	AWZ03_010813	Uncharacterized protein. (161 aa)
	AWZ03_013758	Uncharacterized protein. (235 aa)
	AWZ03_008888	OB_NTP_bind domain-containing protein. (182 aa)

Your Current Organism:

Drosophila navojoa

NCBI taxonomy Id: 7232
Other names: D. navojoa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AWZ03_000214	AWZ03_000698	A0A484BX47	A0A484C013	Protein kinase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.837
AWZ03_000214	AWZ03_000905	A0A484BX47	A0A484BXE1	Protein kinase domain-containing protein.	MFAP1 domain-containing protein.	0.422
AWZ03_000214	AWZ03_001105	A0A484BX47	A0A484BWG5	Protein kinase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.522
AWZ03_000214	AWZ03_001892	A0A484BX47	A0A484BUC8	Protein kinase domain-containing protein.	MPN domain-containing protein.	0.886
AWZ03_000214	AWZ03_001896	A0A484BX47	A0A484BSP6	Protein kinase domain-containing protein.	Small nuclear ribonucleoprotein Sm D3.	0.536
AWZ03_000214	AWZ03_002454	A0A484BX47	A0A484BTL7	Protein kinase domain-containing protein.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.457
AWZ03_000214	AWZ03_003198	A0A484BX47	A0A484BNF0	Protein kinase domain-containing protein.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.745
AWZ03_000214	AWZ03_003252	A0A484BX47	A0A484BNJ8	Protein kinase domain-containing protein.	CPSF_A domain-containing protein.	0.723
AWZ03_000214	AWZ03_003320	A0A484BX47	A0A484BRD5	Protein kinase domain-containing protein.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.531
AWZ03_000214	AWZ03_003664	A0A484BX47	A0A484BMC6	Protein kinase domain-containing protein.	TOG domain-containing protein.	0.871
AWZ03_000214	AWZ03_003880	A0A484BX47	A0A484BN75	Protein kinase domain-containing protein.	Matrin-type domain-containing protein.	0.536
AWZ03_000214	AWZ03_004058	A0A484BX47	A0A484BL98	Protein kinase domain-containing protein.	Uncharacterized protein.	0.785
AWZ03_000214	AWZ03_004115	A0A484BX47	A0A484BML6	Protein kinase domain-containing protein.	PSP domain-containing protein.	0.660
AWZ03_000214	AWZ03_004330	A0A484BX47	A0A484BND6	Protein kinase domain-containing protein.	Tr-type G domain-containing protein.	0.889
AWZ03_000214	AWZ03_004358	A0A484BX47	A0A484BKB6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.636
AWZ03_000214	AWZ03_004750	A0A484BX47	A0A484BJ88	Protein kinase domain-containing protein.	Uncharacterized protein.	0.536
AWZ03_000214	AWZ03_005373	A0A484BX47	A0A484BHG4	Protein kinase domain-containing protein.	Small nuclear ribonucleoprotein Sm D2.	0.661
AWZ03_000214	AWZ03_005417	A0A484BX47	A0A484BJ53	Protein kinase domain-containing protein.	Metalloendopeptidase.	0.447
AWZ03_000214	AWZ03_005621	A0A484BX47	A0A484BGU1	Protein kinase domain-containing protein.	Sm domain-containing protein.	0.463
AWZ03_000214	AWZ03_005744	A0A484BX47	A0A484BIC5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.776