(117 nodes) Catalytic step 2 spliceosome network (Drosophila navojoa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AWZ03_000668	Uncharacterized protein; Belongs to the DEAD box helicase family. (785 aa)
	AWZ03_000905	MFAP1 domain-containing protein. (473 aa)
	AWZ03_000214	Protein kinase domain-containing protein. (932 aa)
	AWZ03_000044	Uncharacterized protein; Belongs to the DEAD box helicase family. (601 aa)
	AWZ03_000626	C2H2-type domain-containing protein. (743 aa)
	AWZ03_001105	WD_REPEATS_REGION domain-containing protein. (570 aa)
	AWZ03_000691	Uncharacterized protein. (349 aa)
	AWZ03_001346	Uncharacterized protein. (624 aa)
	AWZ03_001461	Uncharacterized protein. (1181 aa)
	AWZ03_000739	RRM domain-containing protein. (121 aa)
	AWZ03_001259	Tudor domain-containing protein. (194 aa)
	AWZ03_001892	MPN domain-containing protein. (2397 aa)
	AWZ03_002240	Uncharacterized protein. (343 aa)
	AWZ03_001520	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (173 aa)
	AWZ03_002514	Uncharacterized protein. (883 aa)
	AWZ03_001449	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (149 aa)
	AWZ03_002454	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (645 aa)
	AWZ03_002339	Nitric oxide synthase-interacting protein homolog. (309 aa)
	AWZ03_001896	Small nuclear ribonucleoprotein Sm D3. (151 aa)
	AWZ03_002244	Uncharacterized protein. (355 aa)
	AWZ03_003320	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	AWZ03_002549	KH domain-containing protein. (359 aa)
	AWZ03_003426	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (388 aa)
	AWZ03_003252	CPSF_A domain-containing protein. (1229 aa)
	AWZ03_004380	Uncharacterized protein. (383 aa)
	AWZ03_004350	PPIase cyclophilin-type domain-containing protein. (906 aa)
	AWZ03_003198	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (124 aa)
	AWZ03_004330	Tr-type G domain-containing protein. (976 aa)
	AWZ03_003158	DZF domain-containing protein. (911 aa)
	AWZ03_003880	Matrin-type domain-containing protein. (260 aa)
	AWZ03_004115	PSP domain-containing protein. (744 aa)
	AWZ03_003664	TOG domain-containing protein. (1332 aa)
	AWZ03_003926	CSD_1 domain-containing protein. (334 aa)
	AWZ03_004676	PRP38_assoc domain-containing protein. (365 aa)
	AWZ03_004058	Uncharacterized protein. (1135 aa)
	AWZ03_005176	Nkap_C domain-containing protein. (468 aa)
	AWZ03_004306	Uncharacterized protein; Belongs to the DEAD box helicase family. (507 aa)
	AWZ03_004459	Uncharacterized protein. (1288 aa)
	AWZ03_004750	Uncharacterized protein. (548 aa)
	AWZ03_005417	Metalloendopeptidase. (945 aa)
	AWZ03_005701	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
	AWZ03_004972	DUF667 domain-containing protein. (271 aa)
	AWZ03_005970	Uncharacterized protein. (116 aa)
	AWZ03_005744	Uncharacterized protein. (837 aa)
	AWZ03_006224	Uncharacterized protein. (616 aa)
	AWZ03_005999	RRM domain-containing protein. (277 aa)
	AWZ03_006308	Small nuclear ribonucleoprotein-associated protein. (198 aa)
	AWZ03_006288	Uncharacterized protein; Belongs to the argonaute family. (854 aa)
	AWZ03_005373	Small nuclear ribonucleoprotein Sm D2. (124 aa)
	AWZ03_005750	Uncharacterized protein. (579 aa)
	AWZ03_006015	RRM domain-containing protein. (302 aa)
	AWZ03_007107	WD_REPEATS_REGION domain-containing protein. (308 aa)
	AWZ03_006195	Uncharacterized protein. (817 aa)
	AWZ03_006545	Uncharacterized protein. (250 aa)
	AWZ03_006530	Uncharacterized protein. (643 aa)
	AWZ03_007631	Uncharacterized protein. (278 aa)
	AWZ03_007680	RRM domain-containing protein. (452 aa)
	AWZ03_006876	Uncharacterized protein. (685 aa)
	AWZ03_007654	Uncharacterized protein. (512 aa)
	AWZ03_008755	Uncharacterized protein. (533 aa)
	AWZ03_008199	Sm domain-containing protein. (110 aa)
	AWZ03_009225	Cwf21 domain-containing protein. (169 aa)
	AWZ03_008843	Uncharacterized protein. (226 aa)
	AWZ03_008887	Uncharacterized protein. (536 aa)
	AWZ03_008381	Uncharacterized protein. (1066 aa)
	AWZ03_008361	Uncharacterized protein. (893 aa)
	AWZ03_008488	Uncharacterized protein. (246 aa)
	AWZ03_008717	Uncharacterized protein. (110 aa)
	AWZ03_009090	WD_REPEATS_REGION domain-containing protein. (347 aa)
	AWZ03_008564	Uncharacterized protein. (294 aa)
	AWZ03_008924	Uncharacterized protein. (147 aa)
	AWZ03_009386	Uncharacterized protein. (599 aa)
	AWZ03_009615	PPIase cyclophilin-type domain-containing protein. (505 aa)
	AWZ03_008888	OB_NTP_bind domain-containing protein. (182 aa)
	AWZ03_009101	PWI domain-containing protein. (1095 aa)
	AWZ03_010165	Uncharacterized protein. (1933 aa)
	AWZ03_009226	Uncharacterized protein. (1614 aa)
	AWZ03_009619	G-patch domain-containing protein. (986 aa)
	AWZ03_010640	Uncharacterized protein. (428 aa)
	AWZ03_009702	Uncharacterized protein. (759 aa)
	AWZ03_010812	Uncharacterized protein. (261 aa)
	AWZ03_010396	RRM domain-containing protein. (622 aa)
	AWZ03_010722	Uncharacterized protein. (406 aa)
	AWZ03_010108	Uncharacterized protein. (272 aa)
	AWZ03_010311	Uncharacterized protein. (216 aa)
	AWZ03_010724	BTB domain-containing protein. (170 aa)
	AWZ03_010388	Uncharacterized protein. (962 aa)
	AWZ03_011467	Uncharacterized protein. (906 aa)
	AWZ03_011168	MIF4G domain-containing protein. (495 aa)
	AWZ03_010535	Uncharacterized protein. (517 aa)
	AWZ03_011652	Uncharacterized protein. (144 aa)
	AWZ03_010641	Uncharacterized protein. (625 aa)
	AWZ03_010813	Uncharacterized protein. (161 aa)
	AWZ03_011440	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (577 aa)
	AWZ03_011833	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (303 aa)
	AWZ03_011631	Uncharacterized protein. (498 aa)
	AWZ03_012027	TPR_REGION domain-containing protein. (701 aa)
	AWZ03_011317	Uncharacterized protein. (234 aa)
	AWZ03_012087	Matrin-type domain-containing protein. (503 aa)
	AWZ03_011590	WD_REPEATS_REGION domain-containing protein. (478 aa)
	AWZ03_011664	Uncharacterized protein. (1035 aa)
	AWZ03_011975	Uncharacterized protein. (325 aa)
	AWZ03_011904	Uncharacterized protein. (222 aa)
	AWZ03_012668	Uncharacterized protein. (791 aa)
	AWZ03_012230	Uncharacterized protein. (772 aa)
	AWZ03_013032	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...] (154 aa)
	AWZ03_012588	Septin-interacting protein 1; May be involved in pre-mRNA splicing. Belongs to the TFP11/STIP family. (852 aa)
	AWZ03_012421	Uncharacterized protein. (552 aa)
	AWZ03_012473	DUF2040 domain-containing protein. (392 aa)
	AWZ03_013700	Uncharacterized protein. (255 aa)
	AWZ03_012813	RRM domain-containing protein. (183 aa)
	AWZ03_013057	Small nuclear ribonucleoprotein G. (76 aa)
	AWZ03_014494	Uncharacterized protein. (483 aa)
	AWZ03_013848	C3H1-type domain-containing protein. (970 aa)
	AWZ03_013758	Uncharacterized protein. (235 aa)
	AWZ03_014746	Uncharacterized protein. (163 aa)
	AWZ03_014593	SKIP_SNW domain-containing protein. (543 aa)

Your Current Organism:

Drosophila navojoa

NCBI taxonomy Id: 7232
Other names: D. navojoa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AWZ03_000044	AWZ03_000214	A0A484BWM7	A0A484BX47	Uncharacterized protein; Belongs to the DEAD box helicase family.	Protein kinase domain-containing protein.	0.447
AWZ03_000044	AWZ03_000905	A0A484BWM7	A0A484BXE1	Uncharacterized protein; Belongs to the DEAD box helicase family.	MFAP1 domain-containing protein.	0.543
AWZ03_000044	AWZ03_001105	A0A484BWM7	A0A484BWG5	Uncharacterized protein; Belongs to the DEAD box helicase family.	WD_REPEATS_REGION domain-containing protein.	0.546
AWZ03_000044	AWZ03_001520	A0A484BWM7	A0A484BTV8	Uncharacterized protein; Belongs to the DEAD box helicase family.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.538
AWZ03_000044	AWZ03_002454	A0A484BWM7	A0A484BTL7	Uncharacterized protein; Belongs to the DEAD box helicase family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.427
AWZ03_000044	AWZ03_003252	A0A484BWM7	A0A484BNJ8	Uncharacterized protein; Belongs to the DEAD box helicase family.	CPSF_A domain-containing protein.	0.439
AWZ03_000044	AWZ03_003664	A0A484BWM7	A0A484BMC6	Uncharacterized protein; Belongs to the DEAD box helicase family.	TOG domain-containing protein.	0.681
AWZ03_000044	AWZ03_004058	A0A484BWM7	A0A484BL98	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.514
AWZ03_000044	AWZ03_004115	A0A484BWM7	A0A484BML6	Uncharacterized protein; Belongs to the DEAD box helicase family.	PSP domain-containing protein.	0.417
AWZ03_000044	AWZ03_004306	A0A484BWM7	A0A484BKA1	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.672
AWZ03_000044	AWZ03_004350	A0A484BWM7	A0A484BNF5	Uncharacterized protein; Belongs to the DEAD box helicase family.	PPIase cyclophilin-type domain-containing protein.	0.582
AWZ03_000044	AWZ03_004459	A0A484BWM7	A0A484BK09	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.591
AWZ03_000044	AWZ03_004676	A0A484BWM7	A0A484BLB0	Uncharacterized protein; Belongs to the DEAD box helicase family.	PRP38_assoc domain-containing protein.	0.480
AWZ03_000044	AWZ03_004750	A0A484BWM7	A0A484BJ88	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.476
AWZ03_000044	AWZ03_005176	A0A484BWM7	A0A484BL08	Uncharacterized protein; Belongs to the DEAD box helicase family.	Nkap_C domain-containing protein.	0.497
AWZ03_000044	AWZ03_005701	A0A484BWM7	A0A484BIP3	Uncharacterized protein; Belongs to the DEAD box helicase family.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.538
AWZ03_000044	AWZ03_005999	A0A484BWM7	A0A484BHQ3	Uncharacterized protein; Belongs to the DEAD box helicase family.	RRM domain-containing protein.	0.657
AWZ03_000044	AWZ03_006530	A0A484BWM7	A0A484BE83	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.529
AWZ03_000044	AWZ03_006876	A0A484BWM7	A0A484BCX2	Uncharacterized protein; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.591
AWZ03_000044	AWZ03_008199	A0A484BWM7	A0A484B9H2	Uncharacterized protein; Belongs to the DEAD box helicase family.	Sm domain-containing protein.	0.431