38 items (Drosophila navojoa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

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Your Input:
	KATNA1-2	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (681 aa)
	AWZ03_014222	LisH domain-containing protein. (513 aa)
	AWZ03_013571	AAA domain-containing protein; Belongs to the AAA ATPase family. (405 aa)
	AWZ03_014529	AAA domain-containing protein. (857 aa)
	AWZ03_012477	AAA domain-containing protein; Belongs to the AAA ATPase family. (397 aa)
	AWZ03_011695	Uncharacterized protein; Belongs to the AAA ATPase family. (442 aa)
	AWZ03_012082	AAA domain-containing protein; Belongs to the AAA ATPase family. (339 aa)
	AWZ03_011154	AAA domain-containing protein; Belongs to the AAA ATPase family. (451 aa)
	AWZ03_009960	AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
	AWZ03_010776	AAA domain-containing protein. (995 aa)
	AWZ03_010035	Uncharacterized protein. (745 aa)
	AWZ03_008998	AAA domain-containing protein; Belongs to the AAA ATPase family. (409 aa)
	AWZ03_008479	AAA domain-containing protein. (603 aa)
	AWZ03_008111	AAA domain-containing protein. (331 aa)
	AWZ03_008661	AAA domain-containing protein; Belongs to the AAA ATPase family. (373 aa)
	AWZ03_008322	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (979 aa)
	AWZ03_007148	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (908 aa)
	AWZ03_006913	AAA domain-containing protein; Belongs to the AAA ATPase family. (398 aa)
	AWZ03_006554	AAA domain-containing protein; Belongs to the AAA ATPase family. (434 aa)
	AWZ03_006923	Replication factor C subunit 1. (1009 aa)
	AWZ03_005983	AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
	AWZ03_005730	Uncharacterized protein. (727 aa)
	AWZ03_006705	ATPase_AAA_core domain-containing protein. (777 aa)
	AWZ03_006629	Uncharacterized protein. (672 aa)
	spas	Spastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (765 aa)
	AWZ03_006313	AAA domain-containing protein. (332 aa)
	AWZ03_005371	Uncharacterized protein. (750 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (573 aa)
	AWZ03_004297	AAA domain-containing protein; Belongs to the AAA ATPase family. (392 aa)
	AWZ03_004135	Uncharacterized protein. (802 aa)
	AWZ03_003611	AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
	AWZ03_002114	AAA domain-containing protein. (752 aa)
	AWZ03_011729	AAA domain-containing protein. (839 aa)
	AWZ03_002392	Uncharacterized protein. (1035 aa)
	AWZ03_001760	Uncharacterized protein; Belongs to the AAA ATPase family. (874 aa)
	AWZ03_001343	AAA domain-containing protein. (354 aa)
	AWZ03_000459	Uncharacterized protein. (930 aa)
	AWZ03_000416	AAA domain-containing protein. (813 aa)

Your Current Organism:

Drosophila navojoa

NCBI taxonomy Id: 7232
Other names: D. navojoa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AWZ03_000416	AWZ03_002114	A0A484BVZ4	A0A484BSM2	AAA domain-containing protein.	AAA domain-containing protein.	0.424
AWZ03_000416	AWZ03_006629	A0A484BVZ4	A0A484BGK3	AAA domain-containing protein.	Uncharacterized protein.	0.845
AWZ03_000416	AWZ03_008322	A0A484BVZ4	A0A484BB80	AAA domain-containing protein.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.749
AWZ03_000416	AWZ03_011729	A0A484BVZ4	A0A484AZ13	AAA domain-containing protein.	AAA domain-containing protein.	0.851
AWZ03_001343	AWZ03_001760	A0A484BVL8	A0A484BUF4	AAA domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.491
AWZ03_001343	AWZ03_004135	A0A484BVL8	A0A484BMM9	AAA domain-containing protein.	Uncharacterized protein.	0.498
AWZ03_001343	AWZ03_005730	A0A484BVL8	A0A484BFY3	AAA domain-containing protein.	Uncharacterized protein.	0.500
AWZ03_001343	AWZ03_006313	A0A484BVL8	A0A484BH08	AAA domain-containing protein.	AAA domain-containing protein.	0.999
AWZ03_001343	AWZ03_006923	A0A484BVL8	A0A484BFS7	AAA domain-containing protein.	Replication factor C subunit 1.	0.998
AWZ03_001343	AWZ03_007148	A0A484BVL8	A0A484BCH2	AAA domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.500
AWZ03_001343	AWZ03_008111	A0A484BVL8	A0A484B9U6	AAA domain-containing protein.	AAA domain-containing protein.	0.999
AWZ03_001343	AWZ03_010776	A0A484BVL8	A0A484B4P8	AAA domain-containing protein.	AAA domain-containing protein.	0.981
AWZ03_001343	AWZ03_012082	A0A484BVL8	A0A484B0Z0	AAA domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.536
AWZ03_001760	AWZ03_001343	A0A484BUF4	A0A484BVL8	Uncharacterized protein; Belongs to the AAA ATPase family.	AAA domain-containing protein.	0.491
AWZ03_001760	AWZ03_003611	A0A484BUF4	A0A484BQT7	Uncharacterized protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.646
AWZ03_001760	AWZ03_004297	A0A484BUF4	A0A484BKE5	Uncharacterized protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.507
AWZ03_001760	AWZ03_005983	A0A484BUF4	A0A484BFT3	Uncharacterized protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.637
AWZ03_001760	AWZ03_006313	A0A484BUF4	A0A484BH08	Uncharacterized protein; Belongs to the AAA ATPase family.	AAA domain-containing protein.	0.491
AWZ03_001760	AWZ03_006554	A0A484BUF4	A0A484BE35	Uncharacterized protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.581
AWZ03_001760	AWZ03_006923	A0A484BUF4	A0A484BFS7	Uncharacterized protein; Belongs to the AAA ATPase family.	Replication factor C subunit 1.	0.489