(150 nodes) Morphogenesis of embryonic epithelium network (Drosophila persimilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DperGL25084	GL25084. (851 aa)
	DperGL23544	GL23544. (561 aa)
	DperGL23983	GL23983. (747 aa)
	DperGL23984	GL23984. (219 aa)
	DperGL23524	GL23524. (550 aa)
	DperGL24016	GL24016. (511 aa)
	DperGL24017	GL24017. (967 aa)
	DperGL23098	GL23098. (167 aa)
	DperGL23097	GL23097. (1247 aa)
	DperGL24180	GL24180; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1265 aa)
	DperGL24193	LIM domain-containing protein. (348 aa)
	DperGL23353	Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (395 aa)
	DperGL24256	GL24256. (489 aa)
	DperGL23263	GL23263; Belongs to the DOCK family. (1909 aa)
	DperGL23126	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (519 aa)
	kay	Transcription factor kayak; Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'. May play a role in the function or determination of a particular subset of cells in the developing embryo. It is able to carry out its function either independently of or in conjunction with Jra (By similarity). (526 aa)
	DperGL23693	GL23693. (563 aa)
	DperGL23675	GL23675. (723 aa)
	DperGL23667	GL23667. (3443 aa)
	DperGL23666	GL23666. (173 aa)
	DperGL19093	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (130 aa)
	DperGL18561	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (562 aa)
	DperGL18977	Mitogen-activated protein kinase. (371 aa)
	DperGL18899	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	DperGL19258	GL19258; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	Dpercbt	Cabut. (436 aa)
	DperGL18842	GL18842. (1312 aa)
	DperGL18825	GL18825. (550 aa)
	DperGL18738	GL18738. (725 aa)
	DperGL19386	Tyrosine-protein kinase. (797 aa)
	DperGL19392	Receptor protein-tyrosine kinase. (1578 aa)
	DperGL19400	GL19400. (218 aa)
	DperGL19401	GL19401. (66 aa)
	DperGL19420	GL19420. (749 aa)
	DperGL19515	GL19515. (204 aa)
	DperGL10682	Tyrosine-protein kinase. (938 aa)
	DperGL11468	GL11468. (858 aa)
	DperGL10585	GL10585; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1254 aa)
	DperGL11062	GL11062. (662 aa)
	DperGL10452	GL10452. (557 aa)
	DperGL10938	GL10938. (109 aa)
	DperGL11169	GL11169. (184 aa)
	DperGL11674	GL11674. (70 aa)
	DperGL11705	GL11705. (288 aa)
	DperGL22331	GL22331. (1467 aa)
	DperGL22332	GL22332. (601 aa)
	DperGL22333	GL22333. (208 aa)
	DperGL21877	GL21877. (894 aa)
	DperGL21849	GL21849. (2124 aa)
	DperGL21786	GL21786. (214 aa)
	DperGL21741	GL21741. (547 aa)
	DperGL21740	GL21740. (236 aa)
	DperGL22184	GL22184. (1672 aa)
	DperGL22199	GL22199. (2117 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	DperGL22280	GL22280. (408 aa)
	DperGL22282	GL22282. (275 aa)
	DperGL22283	GL22283. (317 aa)
	DperGL17167	GL17167. (586 aa)
	DperGL17329	GL17329. (711 aa)
	DperGL17135	GL17135. (355 aa)
	DperGL17080	GL17080. (65 aa)
	DperGL17079	GL17079. (4806 aa)
	DperGL16982	Receptor protein-tyrosine kinase. (1439 aa)
	DperGL16900	Non-specific serine/threonine protein kinase. (610 aa)
	DperGL16898	GL16898. (541 aa)
	DperGL17608	GL17608. (293 aa)
	DperGL17634	GL17634. (110 aa)
	DperGL17638	GL17638. (1745 aa)
	DperGL17640	GL17640. (798 aa)
	DperGL16696	Tyrosine-protein kinase. (516 aa)
	DperGL26218	GL26218. (1095 aa)
	DperGL25520	GL25520. (1620 aa)
	DperGL25775	GL25775. (232 aa)
	DperGL26103	GL26103. (476 aa)
	DperGL26105	GL26105. (521 aa)
	DperGL26126	GL26126. (410 aa)
	DperGL25641	GL25641. (125 aa)
	DperGL25640	GL25640. (294 aa)
	DperGL12283	GL12283. (511 aa)
	DperGL12212	GL12212. (1126 aa)
	DperGL13704	GL13704. (195 aa)
	DperGL13676	Tyrosine-protein kinase. (1301 aa)
	DperGL13894	GL13894. (370 aa)
	DperGL15107	GL15107. (453 aa)
	DperGL25083	GL25083. (61 aa)
	DperGL25157	GL25157. (1355 aa)
	DperGL25305	GL25305. (439 aa)
	DperGL25306	GL25306. (371 aa)
	DperGL25307	GL25307. (580 aa)
	DperGL24820	GL24820. (133 aa)
	DperGL26543	GL26543. (1864 aa)
	DperGL24253	GL24253. (192 aa)
	DperGL13008	GL13008. (870 aa)
	DperGL14696	GL14696. (618 aa)
	DperGL14782	GL14782. (1039 aa)
	DperGL16492	GL16492. (1227 aa)
	DperGL16542	GL16542. (780 aa)
	DperGL16424	GL16424. (77 aa)
	DperGL16423	GL16423. (799 aa)
	DperGL20231	GL20231. (194 aa)
	DperGL20230	GL20230. (178 aa)
	DperGL20189	GL20189. (445 aa)
	DperGL20186	GL20186. (612 aa)
	DperGL20185	GL20185. (1219 aa)
	DperGL20367	GL20367. (345 aa)
	DperGL20368	GL20368; Belongs to the MAGUK family. (918 aa)
	DperGL19950	GL19950. (2412 aa)
	DperGL19951	GL19951. (264 aa)
	DperGL27335	GL27335. (423 aa)
	DperGL14856	GL14856. (126 aa)
	DperGL14855	GL14855. (443 aa)
	DperGL14854	GL14854. (213 aa)
	DperGL14851	GL14851. (599 aa)
	DperGL15931	GL15931; Belongs to the protein kinase superfamily. (473 aa)
	DperGL22566	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (470 aa)
	DperGL22508	GL22508. (342 aa)
	DperGL22452	GL22452. (631 aa)
	inx-3	Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (303 aa)
	DperGL26731	Integrin beta; Belongs to the integrin beta chain family. (617 aa)
	DperGL12060	GL12060. (268 aa)
	DperGL12049	GL12049. (247 aa)
	DperGL20711	GL20711. (193 aa)
	DperGL18265	GL18265. (191 aa)
	DperGL18246	GL18246; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa)
	DperGL18245	GL18245; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (420 aa)
	DperGL16165	GL16165. (650 aa)
	DperGL16078	GL16078. (146 aa)
	DperGL20555	GL20555. (192 aa)
	DperGL19957	GL19957. (2107 aa)
	DperGL21936	GL21936. (60 aa)
	DperGL13283	GL13283. (1601 aa)
	DperGL13284	GL13284. (413 aa)
	DperGL12825	GL12825. (1045 aa)
	DperGL12721	GL12721. (386 aa)
	DperGL12720	GL12720. (408 aa)
	DperGL12719	GL12719. (248 aa)
	DperGL21018	GL21018; Belongs to the cytochrome P450 family. (517 aa)
	DperGL24751	GL24751. (1679 aa)
	DperGL24750	GL24750. (90 aa)
	DperGL15988	GL15988. (357 aa)
	DperGL15651	GL15651. (422 aa)
	DperGL27069	GL27069; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1374 aa)
	DperGL17063	GL17063; Belongs to the cytochrome P450 family. (488 aa)
	DperGL25366	GL25366. (588 aa)
	DperGL21419	GL21419. (84 aa)
	DperGL13164	GL13164. (581 aa)
	DperGL15414	GL15414. (90 aa)
	DperGL15363	GL15363. (334 aa)
	DperGL13193	GL13193. (172 aa)

Your Current Organism:

Drosophila persimilis

NCBI taxonomy Id: 7234
Other names: D. persimilis

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DperGL10452	DperGL11705	B4GC48	B4GD62	GL10452.	GL11705.	0.459
DperGL10452	DperGL12212	B4GC48	B4GML9	GL10452.	GL12212.	0.773
DperGL10452	DperGL13008	B4GC48	B4GVD5	GL10452.	GL13008.	0.523
DperGL10452	DperGL13164	B4GC48	B4IQY4	GL10452.	GL13164.	0.457
DperGL10452	DperGL13704	B4GC48	B4GNY0	GL10452.	GL13704.	0.704
DperGL10452	DperGL15414	B4GC48	B4IRD2	GL10452.	GL15414.	0.457
DperGL10452	DperGL16078	B4GC48	B4H5K8	GL10452.	GL16078.	0.733
DperGL10452	DperGL16982	B4GC48	B4GH99	GL10452.	Receptor protein-tyrosine kinase.	0.653
DperGL10452	DperGL18265	B4GC48	B4H4Q6	GL10452.	GL18265.	0.689
DperGL10452	DperGL20555	B4GC48	B4H6A5	GL10452.	GL20555.	0.983
DperGL10452	DperGL21419	B4GC48	B4HD15	GL10452.	GL21419.	0.457
DperGL10452	DperGL21786	B4GC48	B4GEK9	GL10452.	GL21786.	0.449
DperGL10452	DperGL23263	B4GC48	B4G504	GL10452.	GL23263; Belongs to the DOCK family.	0.817
DperGL10452	DperGL24253	B4GC48	B4GUQ6	GL10452.	GL24253.	0.657
DperGL10452	DperGL25305	B4GC48	B4GS16	GL10452.	GL25305.	0.519
DperGL10452	DperGL25306	B4GC48	B4GS17	GL10452.	GL25306.	0.519
DperGL10452	DperGL25307	B4GC48	B4GS18	GL10452.	GL25307.	0.519
DperGL10452	DperGL25366	B4GC48	B4HCW0	GL10452.	GL25366.	0.457
DperGL10452	DperGL27069	B4GC48	B4HAM7	GL10452.	GL27069; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.457
DperGL10585	DperGL11468	B4GB54	B4GAZ6	GL10585; Belongs to the protein kinase superfamily. Tyr protein kinase family.	GL11468.	0.503