(31 nodes) Stem cell differentiation network (Drosophila persimilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DperGL23098	GL23098. (167 aa)
	DperGL23097	GL23097. (1247 aa)
	DperGL23002	GL23002. (562 aa)
	DperGL18899	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	DperGL19515	GL19515. (204 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	DperGL22274	GL22274. (777 aa)
	DperGL17295	GL17295. (196 aa)
	DperGL17467	GL17467. (848 aa)
	DperGL16982	Receptor protein-tyrosine kinase. (1439 aa)
	DperGL16978	Zinc finger FYVE domain-containing protein. (1352 aa)
	DperGL25557	GL25557. (210 aa)
	DperGL25845	GL25845. (376 aa)
	DperGL25843	GL25843. (123 aa)
	DperGL25841	GL25841. (679 aa)
	DperGL12019	Fibroblast growth factor receptor. (725 aa)
	DperGL11971	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (939 aa)
	DperGL12215	GL12215. (532 aa)
	DperGL15087	GL15087. (644 aa)
	DperGL14802	GL14802. (1516 aa)
	DperGL19950	GL19950. (2412 aa)
	DperGL19951	GL19951. (264 aa)
	DperGL27335	GL27335. (423 aa)
	DperGL27353	GL27353. (573 aa)
	DperGL22508	GL22508. (342 aa)
	DperGL17981	GL17981. (225 aa)
	DperGL21009	GL21009; Belongs to the G-protein coupled receptor Fz/Smo family. (395 aa)
	DperGL20917	GL20917; Belongs to the G-protein coupled receptor Fz/Smo family. (701 aa)
	DperGL16258	GL16258. (949 aa)
	DperGL13180	GL13180. (70 aa)
	DperGL15363	GL15363. (334 aa)

Your Current Organism:

Drosophila persimilis

NCBI taxonomy Id: 7234
Other names: D. persimilis

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DperGL11971	DperGL19950	B4GLU3	B4GYL6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GL19950.	0.855
DperGL11971	DperGL19951	B4GLU3	B4GYL7	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GL19951.	0.855
DperGL12019	Ras85D	B4GLK1	B4GFJ8	Fibroblast growth factor receptor.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.534
DperGL12215	DperGL27335	B4GML7	B4GZB3	GL12215.	GL27335.	0.810
DperGL15087	DperGL16982	B4GPX1	B4GH99	GL15087.	Receptor protein-tyrosine kinase.	0.470
DperGL15087	DperGL22508	B4GPX1	B4H1C3	GL15087.	GL22508.	0.591
DperGL15087	Ras85D	B4GPX1	B4GFJ8	GL15087.	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.	0.592
DperGL15363	DperGL16982	B4IRI9	B4GH99	GL15363.	Receptor protein-tyrosine kinase.	0.470
DperGL16258	DperGL16982	B4HBE0	B4GH99	GL16258.	Receptor protein-tyrosine kinase.	0.457
DperGL16982	DperGL15087	B4GH99	B4GPX1	Receptor protein-tyrosine kinase.	GL15087.	0.470
DperGL16982	DperGL15363	B4GH99	B4IRI9	Receptor protein-tyrosine kinase.	GL15363.	0.470
DperGL16982	DperGL16258	B4GH99	B4HBE0	Receptor protein-tyrosine kinase.	GL16258.	0.457
DperGL16982	DperGL18899	B4GH99	B4G845	Receptor protein-tyrosine kinase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.475
DperGL16982	DperGL19950	B4GH99	B4GYL6	Receptor protein-tyrosine kinase.	GL19950.	0.445
DperGL16982	DperGL19951	B4GH99	B4GYL7	Receptor protein-tyrosine kinase.	GL19951.	0.445
DperGL16982	DperGL22274	B4GH99	B4GFT8	Receptor protein-tyrosine kinase.	GL22274.	0.505
DperGL16982	DperGL22508	B4GH99	B4H1C3	Receptor protein-tyrosine kinase.	GL22508.	0.614
DperGL16982	DperGL23097	B4GH99	B4G3H0	Receptor protein-tyrosine kinase.	GL23097.	0.470
DperGL16982	DperGL23098	B4GH99	B4G3G8	Receptor protein-tyrosine kinase.	GL23098.	0.470
DperGL16982	DperGL25557	B4GH99	B4GJ65	Receptor protein-tyrosine kinase.	GL25557.	0.409