(166 nodes) Anatomical structure homeostasis network (Drosophila persimilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DperGL19951	GL19951. (264 aa)
	DperGL19950	GL19950. (2412 aa)
	DperGL19934	GL19934. (867 aa)
	DperGL20322	GL20322. (273 aa)
	DperGL21262	GL21262. (3393 aa)
	DperGL21256	GL21256. (689 aa)
	DperGL21255	GL21255. (666 aa)
	DperGL16568	GL16568. (429 aa)
	DperGL16423	GL16423. (799 aa)
	DperGL16424	GL16424. (77 aa)
	DperGL14776	GL14776. (1036 aa)
	DperGL14553	GL14553. (313 aa)
	DperGL12967	GL12967. (546 aa)
	DperGL12970	Diacylglycerol kinase. (702 aa)
	DperGL24065	GL24065. (901 aa)
	DperGL24077	GL24077. (1800 aa)
	DperGL24099	GL24099. (1763 aa)
	DperGL14173	GL14173. (267 aa)
	DperGL14297	Phosphoinositide phospholipase C. (924 aa)
	DperGL26449	Phosphoglycerate kinase. (415 aa)
	DperGL26543	GL26543. (1864 aa)
	DperGL25307	GL25307. (580 aa)
	DperGL25306	GL25306. (371 aa)
	DperGL25305	GL25305. (439 aa)
	DperGL25094	GL25094. (157 aa)
	DperGL14653	GL14653. (363 aa)
	DperGL15023	GL15023. (666 aa)
	DperGL15032	GL15032. (129 aa)
	DperGL13654	Glucosylceramidase. (560 aa)
	DperGL13655	Glucosylceramidase. (566 aa)
	DperGL13501	GL13501; Belongs to the transient receptor (TC 1.A.4) family. (1251 aa)
	DperGL13515	GL13515. (932 aa)
	DperGL13517	GL13517. (187 aa)
	DperGL13554	GL13554. (1348 aa)
	DperGL12212	GL12212. (1126 aa)
	DperGL12656	GL12656. (888 aa)
	DperGL12655	GL12655. (1045 aa)
	DperGL12654	GL12654. (2310 aa)
	DperGL12076	GL12076. (801 aa)
	DperGL12075	GL12075; Belongs to the PI3/PI4-kinase family. (1563 aa)
	DperGL25782	GL25782. (3957 aa)
	DperGL25882	Integrin beta; Belongs to the integrin beta chain family. (767 aa)
	DperGL26249	GL26249. (1684 aa)
	DperGL16702	GL16702. (519 aa)
	DperGL17250	GL17250. (97 aa)
	DperGL16712	GL16712. (211 aa)
	DperGL16713	GL16713. (187 aa)
	DperGL17743	GL17743. (209 aa)
	DperGL16847	GL16847. (337 aa)
	DperGL17605	GL17605; Belongs to the tumor necrosis factor family. (426 aa)
	DperGL16871	Phosphatidylinositol 3-kinase catalytic subunit type 3. (966 aa)
	DperGL16931	GL16931. (686 aa)
	DperGL17491	Peptidylprolyl isomerase. (214 aa)
	DperGL16982	Receptor protein-tyrosine kinase. (1439 aa)
	DperGL17355	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (317 aa)
	DperGL17135	GL17135. (355 aa)
	DperGL17324	GL17324. (339 aa)
	DperGL17323	GL17323; Belongs to the protein kinase superfamily. (460 aa)
	DperGL17291	GL17291. (909 aa)
	DperGL17208	GL17208. (1499 aa)
	DperGL17211	GL17211. (984 aa)
	DperGL17212	GL17212. (280 aa)
	DperGL17285	GL17285. (1268 aa)
	DperGL22281	GL22281. (299 aa)
	Manf	Mesencephalic astrocyte-derived neurotrophic factor homolog; Required during the maturation of the embryonic nervous system for maintenance of neuronal and cuticular connectivity. Essential for maintenance of dopaminergic neurons and dopamine levels (By similarity); Belongs to the ARMET family. (173 aa)
	DperGL22173	GL22173. (399 aa)
	DperGL20506	GL20506. (438 aa)
	DperGL21706	Tyrosine-protein kinase. (734 aa)
	DperGL21774	GL21774. (329 aa)
	DperGL21808	GL21808. (886 aa)
	DperGL21849	GL21849. (2124 aa)
	DperGL22351	GL22351. (1138 aa)
	DperGL21513	GL21513. (1937 aa)
	DperGL11237	GL11237; Belongs to the protein kinase superfamily. Tyr protein kinase family. (739 aa)
	DperGL10906	GL10906. (174 aa)
	DperGL10428	GL10428; Belongs to the actin-binding proteins ADF family. (150 aa)
	DperGL10958	GL10958. (639 aa)
	DperGL10451	GL10451. (1489 aa)
	DperGL11577	GL11577. (310 aa)
	DperGL10496	GL10496. (784 aa)
	DperGL10497	GL10497. (661 aa)
	DperGL11509	GL11509; Belongs to the AAA ATPase family. (626 aa)
	DperGL11502	GL11502. (1349 aa)
	Lis-1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (411 aa)
	DperGL10711	GL10711. (1362 aa)
	DperGL10727	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (734 aa)
	DperGL11339	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (634 aa)
	DperGL19515	GL19515. (204 aa)
	DperGL19487	GL19487. (317 aa)
	DperGL18825	GL18825. (550 aa)
	DperGL18869	Phosphoinositide phospholipase C. (839 aa)
	DperGL18875	GL18875. (694 aa)
	DperGL18879	GL18879. (355 aa)
	DperGL18881	GL18881. (1159 aa)
	DperGL18887	GL18887. (153 aa)
	DperGL19231	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (530 aa)
	DperGL18903	GL18903; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (767 aa)
	DperGL18904	GL18904; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (389 aa)
	DperGL19564	GL19564. (72 aa)
	DperGL18067	GL18067. (240 aa)
	DperGL18190	GL18190. (151 aa)
	DperGL12866	GL12866. (308 aa)
	DperGL17813	GL17813. (280 aa)
	DperGL19677	GL19677. (310 aa)
	DperGL15610	GL15610. (1573 aa)
	DperGL18910	GL18910. (1069 aa)
	DperGL19206	GL19206. (539 aa)
	DperGL18484	GL18484. (1816 aa)
	DperGL18973	GL18973. (736 aa)
	DperGL18514	GL18514. (719 aa)
	DperGL20613	GL20613. (65 aa)
	DperGL24404	Nicotinamide-nucleotide adenylyltransferase. (266 aa)
	DperGL24291	Sodium/potassium-transporting ATPase subunit alpha. (895 aa)
	DperGL23301	GL23301; Belongs to the G-protein coupled receptor 1 family. (498 aa)
	DperGL24192	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (466 aa)
	DperGL24513	GL24513. (1374 aa)
	DperGL24017	GL24017. (967 aa)
	DperGL24016	GL24016. (511 aa)
	DperGL24002	GL24002. (598 aa)
	DperGL23984	GL23984. (219 aa)
	DperGL23983	GL23983. (747 aa)
	DperGL11885	GL11885. (315 aa)
	DperGL21357	GL21357. (127 aa)
	DperGL22413	GL22413. (93 aa)
	DperGL18390	GL18390. (1700 aa)
	DperGL10342	GL10342. (1395 aa)
	DperGL10340	GL10340. (1032 aa)
	DperGL10292	GL10292. (401 aa)
	DperGL20917	GL20917; Belongs to the G-protein coupled receptor Fz/Smo family. (701 aa)
	DperGL21009	GL21009; Belongs to the G-protein coupled receptor Fz/Smo family. (395 aa)
	DperGL27046	GL27046. (447 aa)
	DperGL26967	GL26967. (317 aa)
	DperGL27044	GL27044. (539 aa)
	DperGL27023	GL27023. (50 aa)
	DperGL27022	GL27022. (301 aa)
	DperGL11808	GL11808. (115 aa)
	DperGL11807	GL11807. (241 aa)
	DperGL21927	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (410 aa)
	DperGL20359	GL20359. (298 aa)
	DperGL24578	GL24578. (976 aa)
	DperGL24602	GL24602. (367 aa)
	DperGL10079	GL10079. (322 aa)
	DperGL10088	GL10088. (864 aa)
	DperGL10186	GL10186; Cadherins are calcium-dependent cell adhesion proteins. (1356 aa)
	DperGL18312	GL18312. (2531 aa)
	DperGL18307	GL18307. (620 aa)
	DperGL20793	GL20793. (158 aa)
	sws	Neuropathy target esterase sws; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy. Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain. Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain (By similarity); Belongs to t [...] (1435 aa)
	DperGL12060	GL12060. (268 aa)
	DperGL13410	GL13410; Belongs to the integrin alpha chain family. (901 aa)
	DperGL13409	GL13409. (192 aa)
	DperGL13314	GL13314. (745 aa)
	DperGL13421	GL13421. (560 aa)
	DperGL26731	Integrin beta; Belongs to the integrin beta chain family. (617 aa)
	DperGL26767	GL26767; Belongs to the integrin alpha chain family. (1325 aa)
	DperGL17894	GL17894. (303 aa)
	DperGL22508	GL22508. (342 aa)
	DperGL22532	GL22532. (2787 aa)
	DperGL22545	GL22545. (219 aa)
	DperGL15848	GL15848. (365 aa)
	DperGL14851	GL14851. (599 aa)
	DperGL14863	GL14863; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa)
	DperGL22897	GL22897. (778 aa)
	DperGL22834	GL22834. (147 aa)
	DperGL27356	GL27356. (386 aa)
	DperGL27230	GL27230. (1117 aa)

Your Current Organism:

Drosophila persimilis

NCBI taxonomy Id: 7234
Other names: D. persimilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DperGL10079	DperGL18307	B4H5C0	B4H4Q8	GL10079.	GL18307.	0.795
DperGL10186	DperGL16982	B4H4Y5	B4GH99	GL10186; Cadherins are calcium-dependent cell adhesion proteins.	Receptor protein-tyrosine kinase.	0.599
DperGL10186	DperGL20506	B4H4Y5	B4GF09	GL10186; Cadherins are calcium-dependent cell adhesion proteins.	GL20506.	0.496
DperGL10186	DperGL21009	B4H4Y5	B4H824	GL10186; Cadherins are calcium-dependent cell adhesion proteins.	GL21009; Belongs to the G-protein coupled receptor Fz/Smo family.	0.472
DperGL10186	DperGL21357	B4H4Y5	B4HB96	GL10186; Cadherins are calcium-dependent cell adhesion proteins.	GL21357.	0.472
DperGL10186	DperGL21706	B4H4Y5	B4GF08	GL10186; Cadherins are calcium-dependent cell adhesion proteins.	Tyrosine-protein kinase.	0.496
DperGL10186	DperGL21849	B4H4Y5	B4GEC0	GL10186; Cadherins are calcium-dependent cell adhesion proteins.	GL21849.	0.523
DperGL10186	DperGL26731	B4H4Y5	B4H2U1	GL10186; Cadherins are calcium-dependent cell adhesion proteins.	Integrin beta; Belongs to the integrin beta chain family.	0.406
DperGL10292	DperGL13501	B4H9J2	B4GNE7	GL10292.	GL13501; Belongs to the transient receptor (TC 1.A.4) family.	0.812
DperGL10292	DperGL14297	B4H9J2	B4GTC4	GL10292.	Phosphoinositide phospholipase C.	0.595
DperGL10292	DperGL14653	B4H9J2	B4GQ70	GL10292.	GL14653.	0.889
DperGL10292	DperGL14851	B4H9J2	B4H0H8	GL10292.	GL14851.	0.590
DperGL10292	DperGL18903	B4H9J2	B4G841	GL10292.	GL18903; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.949
DperGL10292	DperGL18904	B4H9J2	B4G840	GL10292.	GL18904; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.514
DperGL10292	DperGL25305	B4H9J2	B4GS16	GL10292.	GL25305.	0.410
DperGL10292	DperGL25306	B4H9J2	B4GS17	GL10292.	GL25306.	0.410
DperGL10292	DperGL25307	B4H9J2	B4GS18	GL10292.	GL25307.	0.410
DperGL10428	DperGL15023	B4GCI6	B4GPY9	GL10428; Belongs to the actin-binding proteins ADF family.	GL15023.	0.837
DperGL10428	DperGL15032	B4GCI6	B4GPY8	GL10428; Belongs to the actin-binding proteins ADF family.	GL15032.	0.837
DperGL10428	DperGL22532	B4GCI6	B4H179	GL10428; Belongs to the actin-binding proteins ADF family.	GL22532.	0.414