97 items (Drosophila persimilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GL23610	Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. (1009 aa)
	DperGL23391	GL23391. (207 aa)
	DperGL23389	GL23389. (88 aa)
	DperGL24310	GL24310. (364 aa)
	DperGL24343	GL24343. (122 aa)
	DperGL24424	GL24424; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (652 aa)
	DperGL23796	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (253 aa)
	DperGL18500	GL18500. (112 aa)
	DperGL19174	GL19174. (546 aa)
	DperGL18964	GL18964. (81 aa)
	DperGL19242	GL19242. (456 aa)
	DperGL19515	GL19515. (204 aa)
	DperGL10599	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (211 aa)
	DperGL11590	GL11590. (212 aa)
	DperGL11127	GL11127. (285 aa)
	DperGL11660	GL11660. (182 aa)
	DperGL10906	GL10906. (174 aa)
	DperGL10825	GL10825. (536 aa)
	DperGL22339	GL22339. (529 aa)
	DperGL21825	GL21825. (256 aa)
	DperGL21729	GL21729. (871 aa)
	DperGL22153	GL22153. (360 aa)
	DperGL22155	GL22155. (65 aa)
	DperGL22156	GL22156. (594 aa)
	DperGL21660	GL21660. (311 aa)
	DperGL21638	GL21638. (240 aa)
	DperGL21633	GL21633. (226 aa)
	DperGL22241	GL22241. (1059 aa)
	DperGL17362	GL17362. (429 aa)
	DperGL17373	GL17373. (349 aa)
	DperGL17460	GL17460. (2409 aa)
	DperGL16978	Zinc finger FYVE domain-containing protein. (1352 aa)
	DperGL17676	GL17676. (410 aa)
	DperGL16791	GL16791. (874 aa)
	DperGL17779	GL17779. (125 aa)
	DperGL25782	GL25782. (3957 aa)
	DperGL12550	GL12550. (532 aa)
	DperGL12331	GL12331. (223 aa)
	DperGL13919	GL13919. (167 aa)
	DperGL13948	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (832 aa)
	DperGL14048	GL14048. (270 aa)
	DperGL15087	GL15087. (644 aa)
	DperGL15595	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (182 aa)
	DperGL14499	GL14499. (128 aa)
	DperGL14353	GL14353. (858 aa)
	DperGL16151	GL16151. (485 aa)
	DperGL25041	GL25041. (287 aa)
	DperGL25031	GL25031. (208 aa)
	DperGL24815	GL24815; Belongs to the CD36 family. (529 aa)
	DperGL26446	GL26446. (319 aa)
	DperGL26666	GL26666. (332 aa)
	DperGL14422	GL14422. (861 aa)
	DperGL25475	GL25475. (393 aa)
	DperGL25481	GL25481. (344 aa)
	DperGL25498	GL25498. (209 aa)
	DperGL25499	GL25499. (68 aa)
	DperGL14738	Secretory carrier-associated membrane protein. (342 aa)
	DperGL21269	GL21269. (239 aa)
	DperGL21142	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (848 aa)
	DperGL20223	GL20223. (671 aa)
	DperGL19837	GL19837. (228 aa)
	wls	Protein wntless; A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exos [...] (562 aa)
	DperGL22691	GL22691. (198 aa)
	DperGL14911	GL14911. (192 aa)
	DperGL22508	GL22508. (342 aa)
	DperGL22503	GL22503. (344 aa)
	DperGL22617	GL22617. (212 aa)
	DperGL22630	GL22630. (614 aa)
	DperGL18030	GL18030. (184 aa)
	DperGL18031	GL18031. (617 aa)
	DperGL26868	GL26868. (103 aa)
	DperGL12466	GL12466. (320 aa)
	DperGL11872	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (263 aa)
	DperGL20732	GL20732. (189 aa)
	DperGL20823	GL20823. (399 aa)
	DperGL20824	GL20824; Belongs to the PI3/PI4-kinase family. (1478 aa)
	DperGL20850	GL20850. (408 aa)
	DperGL18219	GL18219. (385 aa)
	DperGL10146	GL10146. (132 aa)
	DperGL10224	GL10224. (585 aa)
	DperGL16055	GL16055. (121 aa)
	DperGL20621	GL20621. (609 aa)
	DperGL21669	GL21669. (399 aa)
	DperGL20026	GL20026; Belongs to the synaptobrevin family. (218 aa)
	DperGL20017	GL20017. (3339 aa)
	DperGL15697	GL15697. (330 aa)
	DperGL20871	GL20871. (659 aa)
	DperGL22971	GL22971. (127 aa)
	DperGL22972	GL22972. (178 aa)
	DperGL21382	GL21382. (201 aa)
	DperGL16284	GL16284. (394 aa)
	DperGL17141	GL17141. (408 aa)
	DperGL11913	GL11913. (447 aa)
	DperGL14148	GL14148. (403 aa)
	DperGL19677	GL19677. (310 aa)
	DperGL18079	GL18079. (235 aa)
	DperGL10057	GL10057. (125 aa)

Your Current Organism:

Drosophila persimilis

NCBI taxonomy Id: 7234
Other names: D. persimilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DperGL10599	DperGL10906	B4GB33	B4GD13	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL10906.	0.992
DperGL10599	DperGL11590	B4GB33	B4GC16	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL11590.	0.953
DperGL10599	DperGL11913	B4GB33	B4HBV5	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL11913.	0.833
DperGL10599	DperGL12331	B4GB33	B4GM56	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL12331.	0.928
DperGL10599	DperGL12466	B4GB33	B4H3G2	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL12466.	0.687
DperGL10599	DperGL14911	B4GB33	B4H081	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL14911.	0.993
DperGL10599	DperGL20850	B4GB33	B4H4C4	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL20850.	0.999
DperGL10599	DperGL21382	B4GB33	B4HAA1	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL21382.	0.989
DperGL10599	DperGL21633	B4GB33	B4GFF2	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL21633.	0.998
DperGL10599	DperGL21669	B4GB33	B4H6V4	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL21669.	0.996
DperGL10599	DperGL21825	B4GB33	B4GEF8	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL21825.	0.937
DperGL10599	DperGL22339	B4GB33	B4GDV6	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL22339.	0.411
DperGL10599	DperGL22617	B4GB33	B4H1I5	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL22617.	0.734
DperGL10599	DperGL22691	B4GB33	B4GZZ6	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL22691.	0.766
DperGL10599	DperGL23796	B4GB33	B4G626	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.967
DperGL10599	DperGL25031	B4GB33	B4GR33	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	GL25031.	0.773
DperGL10906	DperGL10599	B4GD13	B4GB33	GL10906.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.992
DperGL10906	DperGL11590	B4GD13	B4GC16	GL10906.	GL11590.	0.998
DperGL10906	DperGL11913	B4GD13	B4HBV5	GL10906.	GL11913.	0.877
DperGL10906	DperGL12331	B4GD13	B4GM56	GL10906.	GL12331.	0.928