(45 nodes) Ubiquitin-conjugating enzyme E2 network (Drosophila persimilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DperGL24789	GL24789. (85 aa)
	GL16001	Ubiquitin-conjugating enzyme E2 S; Catalyzes the covalent attachment of ubiquitin to other proteins. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating polyubiquitin chains initiated by the E2 enzyme vih/UbcH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. (209 aa)
	DperGL20899	GL20899. (389 aa)
	DperGL12716	GL12716; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
	cbx	Protein crossbronx; Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily. (244 aa)
	DperGL18350	GL18350; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
	DperGL20714	GL20714. (140 aa)
	DperGL11784	GL11784. (202 aa)
	DperGL12148	GL12148. (145 aa)
	DperGL13385	GL13385. (390 aa)
	DperGL26898	GL26898; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	DperGL26777	GL26777. (211 aa)
	DperGL22516	GL22516. (220 aa)
	DperGL22563	GL22563; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	DperGL14825	GL14825; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	DperGL22788	GL22788. (136 aa)
	DperGL22791	GL22791. (80 aa)
	DperGL22792	GL22790. (285 aa)
	DperGL22793	GL22793. (283 aa)
	DperGL20230	GL20230. (178 aa)
	DperGL20231	GL20231. (194 aa)
	DperGL16404	GL16404. (112 aa)
	DperGL25518	GL25518; Belongs to the ubiquitin-conjugating enzyme family. (259 aa)
	DperGL25212	GL25212. (86 aa)
	DperGL26387	GL26387; Belongs to the ubiquitin-conjugating enzyme family. (228 aa)
	DperGL25195	GL25195; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
	DperGL16225	GL16225. (290 aa)
	DperGL15781	GL15781. (284 aa)
	DperGL14565	GL14565. (283 aa)
	DperGL14576	GL14576. (282 aa)
	DperGL15422	GL15422. (488 aa)
	DperGL13836	GL13836. (1404 aa)
	DperGL12172	GL12172; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	DperGL12289	GL12289; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
	DperGL17270	GL17270; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	DperGL17305	GL17305. (154 aa)
	DperGL21579	GL21579. (192 aa)
	DperGL22213	GL22213; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	GL11711	Protein crossbronx-like; Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily. (262 aa)
	DperGL19266	GL19266; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	DperGL19258	GL19258; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
	DperGL23670	GL23670; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	DperGL23835	GL23835. (4950 aa)
	DperGL24447	GL24447; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
	DperGL23929	GL23929. (282 aa)

Your Current Organism:

Drosophila persimilis

NCBI taxonomy Id: 7234
Other names: D. persimilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DperGL11784	DperGL12148	B4H3J2	B4H3B7	GL11784.	GL12148.	0.734
DperGL11784	DperGL12172	B4H3J2	B4GMT8	GL11784.	GL12172; Belongs to the ubiquitin-conjugating enzyme family.	0.416
DperGL11784	DperGL12289	B4H3J2	B4GMA1	GL11784.	GL12289; Belongs to the ubiquitin-conjugating enzyme family.	0.449
DperGL11784	DperGL13385	B4H3J2	B4H356	GL11784.	GL13385.	0.480
DperGL11784	DperGL13836	B4H3J2	B4GP90	GL11784.	GL13836.	0.457
DperGL11784	DperGL14576	B4H3J2	B4GQ79	GL11784.	GL14576.	0.558
DperGL11784	DperGL14825	B4H3J2	B4H0K9	GL11784.	GL14825; Belongs to the ubiquitin-conjugating enzyme family.	0.661
DperGL11784	DperGL15422	B4H3J2	B4GPU8	GL11784.	GL15422.	0.551
DperGL11784	DperGL16225	B4H3J2	B4GQK6	GL11784.	GL16225.	0.418
DperGL11784	DperGL16404	B4H3J2	B4GWM7	GL11784.	GL16404.	0.452
DperGL11784	DperGL17270	B4H3J2	B4GIV0	GL11784.	GL17270; Belongs to the ubiquitin-conjugating enzyme family.	0.416
DperGL11784	DperGL17305	B4H3J2	B4GG88	GL11784.	GL17305.	0.550
DperGL11784	DperGL18350	B4H3J2	B4H4L3	GL11784.	GL18350; Belongs to the ubiquitin-conjugating enzyme family.	0.564
DperGL11784	DperGL19258	B4H3J2	B4G891	GL11784.	GL19258; Belongs to the ubiquitin-conjugating enzyme family.	0.484
DperGL11784	DperGL19266	B4H3J2	B4G8A7	GL11784.	GL19266; Belongs to the ubiquitin-conjugating enzyme family.	0.409
DperGL11784	DperGL20230	B4H3J2	B4GXP6	GL11784.	GL20230.	0.484
DperGL11784	DperGL20231	B4H3J2	B4GXP5	GL11784.	GL20231.	0.484
DperGL11784	DperGL20899	B4H3J2	B4H975	GL11784.	GL20899.	0.480
DperGL11784	DperGL21579	B4H3J2	B4GFR3	GL11784.	GL21579.	0.511
DperGL11784	DperGL22213	B4H3J2	B4GFH3	GL11784.	GL22213; Belongs to the ubiquitin-conjugating enzyme family.	0.578