STRINGSTRING
DperGL23908 DperGL23908 DperGL23560 DperGL23560 DperGL23517 DperGL23517 DperGL23505 DperGL23505 DperGL24182 DperGL24182 DperGL24255 DperGL24255 WRNexo WRNexo DperGL24394 DperGL24394 DperGL19555 DperGL19555 DperGL19629 DperGL19629 DperGL19650 DperGL19650 DperGL19651 DperGL19651 DperGL19266 DperGL19266 DperGL19475 DperGL19475 slx1 slx1 DperGL17307 DperGL17307 DperGL17546 DperGL17546 DperGL25721 DperGL25721 DperGL12075 DperGL12075 DperGL12076 DperGL12076 DperGL12271 DperGL12271 DperGL13479 DperGL13479 DperGL14311 DperGL14311 DperGL25194 DperGL25194 DperGL25208 DperGL25208 DperGL25252 DperGL25252 DperGL25269 DperGL25269 DperGL24844 DperGL24844 DperGL25284 DperGL25284 DperGL14215 DperGL14215 DperGL24569 DperGL24569 DperGL24576 DperGL24576 DperGL21219 DperGL21219 DperGL21139 DperGL21139 DperGL21125 DperGL21125 DperGL20619 DperGL20619 DperGL20284 DperGL20284 DperGL19863 DperGL19863 DperGL27348 DperGL27348 DperGL14973 DperGL14973 DperGL26791 DperGL26791 DperGL20814 DperGL20814 DperGL20815 DperGL20815 DperGL18220 DperGL18220 DperGL10207 DperGL10207 DperGL20217 DperGL20217 DperGL20939 DperGL20939 DperGL18385 DperGL18385 DperGL18384 DperGL18384 DperGL21385 DperGL21385 DperGL21384 DperGL21384 DperGL16334 DperGL16334 DperGL21333 DperGL21333 DperGL22221 DperGL22221 DperGL21439 DperGL21439 DperGL18118 DperGL18118
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DperGL23908GL23908. (191 aa)
DperGL23560Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
DperGL23517GL23517. (1966 aa)
DperGL23505GL23505. (348 aa)
DperGL24182Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
DperGL24255GL24255. (797 aa)
WRNexoWerner Syndrome-like exonuclease; Essential for the formation of DNA replication focal centers. Has an important role in maintaining genome stability. Has exonuclease activity on both single-stranded and duplex templates bearing overhangs, but not blunt ended duplex DNA, and cleaves in a 3'-5' direction (By similarity); Belongs to the WRNexo family. (355 aa)
DperGL24394GL24394. (1390 aa)
DperGL19555Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (621 aa)
DperGL19629TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (301 aa)
DperGL19650GL19650. (88 aa)
DperGL19651GL19651. (397 aa)
DperGL19266GL19266; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
DperGL19475GL19475. (1340 aa)
slx1Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (291 aa)
DperGL17307GL17307. (309 aa)
DperGL17546GL17546. (1312 aa)
DperGL25721GL25721. (430 aa)
DperGL12075GL12075; Belongs to the PI3/PI4-kinase family. (1563 aa)
DperGL12076GL12076. (801 aa)
DperGL12271GL12271. (578 aa)
DperGL13479DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (335 aa)
DperGL14311Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (397 aa)
DperGL25194GL25194. (216 aa)
DperGL25208GL25208. (646 aa)
DperGL25252GL25252. (326 aa)
DperGL25269GL25269. (397 aa)
DperGL24844GL24844. (507 aa)
DperGL25284GL25284. (517 aa)
DperGL14215GL14215. (419 aa)
DperGL24569GL24569. (187 aa)
DperGL24576GL24576. (485 aa)
DperGL21219DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1178 aa)
DperGL21139GL21139. (967 aa)
DperGL21125GL21125. (557 aa)
DperGL20619GL20619. (231 aa)
DperGL20284GL20284. (382 aa)
DperGL19863GL19863. (1431 aa)
DperGL27348GL27348; Belongs to the protein kinase superfamily. (314 aa)
DperGL14973GL14973. (575 aa)
DperGL26791Serine/threonine-protein phosphatase. (307 aa)
DperGL20814GL20814. (237 aa)
DperGL20815GL20815; Belongs to the cyclin family. (306 aa)
DperGL18220GL18220. (485 aa)
DperGL10207GL10207. (234 aa)
DperGL20217GL20217. (1243 aa)
DperGL20939GL20939. (1339 aa)
DperGL18385GL18385. (111 aa)
DperGL18384GL18384. (90 aa)
DperGL21385Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (174 aa)
DperGL21384GL21384. (337 aa)
DperGL16334GL16334. (792 aa)
DperGL21333GL21333. (682 aa)
DperGL22221Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
DperGL21439GL21439. (297 aa)
DperGL18118GL18118. (117 aa)
Your Current Organism:
Drosophila persimilis
NCBI taxonomy Id: 7234
Other names: D. persimilis
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