STRINGSTRING
DperGL23560 DperGL23560 DperGL23517 DperGL23517 DperGL24182 DperGL24182 DperGL24394 DperGL24394 DperGL19555 DperGL19555 DperGL19629 DperGL19629 DperGL19266 DperGL19266 DperGL17546 DperGL17546 DperGL12075 DperGL12075 DperGL12076 DperGL12076 DperGL14311 DperGL14311 DperGL25208 DperGL25208 DperGL25252 DperGL25252 DperGL21219 DperGL21219 DperGL19863 DperGL19863 DperGL27348 DperGL27348 DperGL14973 DperGL14973 DperGL26791 DperGL26791 DperGL20814 DperGL20814 DperGL20815 DperGL20815 DperGL21385 DperGL21385 DperGL21384 DperGL21384 DperGL16334 DperGL16334 DperGL22221 DperGL22221 DperGL21439 DperGL21439 DperGL18118 DperGL18118
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DperGL23560Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
DperGL23517GL23517. (1966 aa)
DperGL24182Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
DperGL24394GL24394. (1390 aa)
DperGL19555Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (621 aa)
DperGL19629TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (301 aa)
DperGL19266GL19266; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
DperGL17546GL17546. (1312 aa)
DperGL12075GL12075; Belongs to the PI3/PI4-kinase family. (1563 aa)
DperGL12076GL12076. (801 aa)
DperGL14311Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (397 aa)
DperGL25208GL25208. (646 aa)
DperGL25252GL25252. (326 aa)
DperGL21219DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1178 aa)
DperGL19863GL19863. (1431 aa)
DperGL27348GL27348; Belongs to the protein kinase superfamily. (314 aa)
DperGL14973GL14973. (575 aa)
DperGL26791Serine/threonine-protein phosphatase. (307 aa)
DperGL20814GL20814. (237 aa)
DperGL20815GL20815; Belongs to the cyclin family. (306 aa)
DperGL21385Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (174 aa)
DperGL21384GL21384. (337 aa)
DperGL16334GL16334. (792 aa)
DperGL22221Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
DperGL21439GL21439. (297 aa)
DperGL18118GL18118. (117 aa)
Your Current Organism:
Drosophila persimilis
NCBI taxonomy Id: 7234
Other names: D. persimilis
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