(48 nodes) Hippo signaling pathway - fly network (Drosophila persimilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DperGL23097	GL23097. (1247 aa)
	DperGL24215	GL24215. (219 aa)
	DperGL23674	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (498 aa)
	DperGL23671	GL23671. (628 aa)
	DperGL18563	GL18563. (1975 aa)
	DperGL18518	GL18518. (1090 aa)
	DperGL19005	GL19005. (269 aa)
	DperGL18977	Mitogen-activated protein kinase. (371 aa)
	DperGL19226	GL19226. (656 aa)
	DperGL18899	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
	DperGL18842	GL18842. (1312 aa)
	DperGL18646	Serine/threonine-protein phosphatase. (309 aa)
	DperGL10521	GL10521. (661 aa)
	DperGL10424	GL10424. (317 aa)
	DperGL11705	GL11705. (288 aa)
	DperGL21790	GL21790; Belongs to the 14-3-3 family. (262 aa)
	DperGL17605	GL17605; Belongs to the tumor necrosis factor family. (426 aa)
	DperGL17609	GL17609; Belongs to the 14-3-3 family. (248 aa)
	DperGL17757	GL17757. (640 aa)
	DperGL26131	GL26131; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1274 aa)
	DperGL13988	GL13988. (1126 aa)
	DperGL13827	GL13827. (822 aa)
	DperGL15349	GL15349. (1812 aa)
	DperGL16483	GL16483. (5086 aa)
	DperGL13933	GL13933. (1397 aa)
	DperGL25008	GL25008. (284 aa)
	DperGL25227	GL25227. (231 aa)
	DperGL25307	GL25307. (580 aa)
	DperGL26531	Mothers against decapentaplegic homolog. (455 aa)
	DperGL25387	GL25387; Belongs to the 14-3-3 family. (250 aa)
	DperGL13122	GL13122. (413 aa)
	DperGL19872	GL19872. (1204 aa)
	DperGL27353	GL27353. (573 aa)
	DperGL27356	GL27356. (386 aa)
	DperGL14888	GL14888. (376 aa)
	DperGL14854	GL14854. (213 aa)
	DperGL15011	GL15011. (687 aa)
	DperGL18307	GL18307. (620 aa)
	DperGL15500	GL15500. (590 aa)
	DperGL27022	GL27022. (301 aa)
	DperGL27044	GL27044. (539 aa)
	DperGL27046	GL27046. (447 aa)
	DperGL18382	GL18382. (647 aa)
	DperGL15988	GL15988. (357 aa)
	DperGL21406	GL21406. (633 aa)
	DperGL15439	GL15439; Belongs to the cyclin family. (721 aa)
	DperGL22923	GL22923. (637 aa)
	DperGL13193	GL13193. (172 aa)

Your Current Organism:

Drosophila persimilis

NCBI taxonomy Id: 7234
Other names: D. persimilis

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DperGL10424	DperGL10521	B4GCJ5	B4GBG4	GL10424.	GL10521.	0.977
DperGL10424	DperGL11705	B4GCJ5	B4GD62	GL10424.	GL11705.	0.488
DperGL10424	DperGL13122	B4GCJ5	B4GV98	GL10424.	GL13122.	0.438
DperGL10424	DperGL13827	B4GCJ5	B4GP70	GL10424.	GL13827.	0.433
DperGL10424	DperGL13988	B4GCJ5	B4GNB6	GL10424.	GL13988.	0.999
DperGL10424	DperGL17609	B4GCJ5	B4GHX2	GL10424.	GL17609; Belongs to the 14-3-3 family.	0.815
DperGL10424	DperGL18563	B4GCJ5	B4G6P7	GL10424.	GL18563.	0.422
DperGL10424	DperGL18842	B4GCJ5	B4G8G3	GL10424.	GL18842.	0.466
DperGL10424	DperGL21790	B4GCJ5	B4GEK3	GL10424.	GL21790; Belongs to the 14-3-3 family.	0.815
DperGL10424	DperGL22923	B4GCJ5	B4HC05	GL10424.	GL22923.	0.999
DperGL10424	DperGL24215	B4GCJ5	B4G4N9	GL10424.	GL24215.	0.873
DperGL10424	DperGL25387	B4GCJ5	B4GU54	GL10424.	GL25387; Belongs to the 14-3-3 family.	0.815
DperGL10424	DperGL26531	B4GCJ5	B4GSG1	GL10424.	Mothers against decapentaplegic homolog.	0.645
DperGL10424	DperGL27353	B4GCJ5	B4GZF8	GL10424.	GL27353.	0.919
DperGL10521	DperGL10424	B4GBG4	B4GCJ5	GL10521.	GL10424.	0.977
DperGL10521	DperGL13827	B4GBG4	B4GP70	GL10521.	GL13827.	0.999
DperGL10521	DperGL13988	B4GBG4	B4GNB6	GL10521.	GL13988.	0.997
DperGL10521	DperGL22923	B4GBG4	B4HC05	GL10521.	GL22923.	0.491
DperGL10521	DperGL23671	B4GBG4	B4G6D6	GL10521.	GL23671.	0.862
DperGL10521	DperGL24215	B4GBG4	B4G4N9	GL10521.	GL24215.	0.998